1. Metabolic rates of groundwater species as a function of body mass and temperatureTiziana Di Lorenzo, Nataša Mori, Tatjana Simčič, 2024, review article Abstract: Research on the metabolic physiology of groundwater species, particularly regarding oxygen consumption
rates (OCR), has made significant advancement, revealing valuable insights into the adaptations of exclusively
groundwater-dwelling (stygobitic) species. However, a comprehensive understanding of how these metabolic
rates scale with body mass and respond to temperature changes remains elusive. This study aims to bridge this
gap by reviewing published data on OCR across a variety of groundwater organisms to elucidate patterns of
metabolic rates in relation to body size and temperature. We employed a combination of literature review and
quantitative analyses, focusing on the allometric scaling of OCR with body weight and the effect of temperature on metabolic rates. Our findings indicate that OCR scales with body weight in an allometric pattern,
with an inter-species slope of 0.80, suggesting non-isometric scaling. Furthermore, our analysis showed that
stygobitic species’ metabolic rates are less responsive to warming than those of non-stygobitic species at low to
moderate temperatures. However, at higher temperatures, metabolic rates in stygobitic species decline faster
than in non-stygobitic taxa, highlighting a potential vulnerability to global climate change. This study contributes to our understanding of the metabolic strategies of groundwater species, underscoring the need for further
research to fully grasp the eco-evolutionary implications of these findings for groundwater conservation.
Keywords: allometry, Arrhenius equation, ectotherms, metabolism, oxygen consumption rate, respiration, stygobiont
Published in DiRROS: 13.09.2024; Views: 0; Downloads: 4
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2. Poročilo o preskusu št.: LVG 2024-120 : vzorec št. 2024/00622Nikica Ogris, Špela Hočevar, Barbara Piškur, 2024, expertise, arbitration decision Keywords: varstvo gozdov, morfološke analize, bor, borov smolasti rak, karantenski škodljiv organizem, Diplodia pinea, sušica najmlajših borovih poganjkov
Published in DiRROS: 12.09.2024; Views: 51; Downloads: 0
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3. Morfološka variabilnost črnike (Quercus ilex L.) v SlovenijiMartin Jež, Robert Brus, Kristjan Jarni, 2024, original scientific article Abstract: V članku je predstavljena črnika (Quercus ilex L.), ena glavnih drevesnih vrst evmediteranske flore na območju Slovenije, kjer raste na razpršenih nahajališčih na severni meji svojega naravnega areala. Glavni namen raziskave je bil preučiti morfološko variabilnost njenih listov. V raziskavo je bilo vključenih sedem naravnih populacij črnike v Sloveniji. Morfometrijska analiza je pokazala veliko variabilnost listov in značilne razlike med populacijami, ki smo jih potrdili pri skoraj vseh preučevanih morfoloških znakih. Na podlagi ugotovljenih morfoloških razlik lahko slovenske populacije razdelimo v tri geografskomorfološke skupine: i) populacije na Goriškem (Sabotin, Sv. Gora in Lijak), ii) Nanos - Osp in iii) populaciji v dolini reke Dragonje. Morfološka variabilnost kot odsev genetske variabilnosti je posledica prilagoditve na lokalne okoljske razmere. Črnika v Sloveniji za zdaj ni ogrožena vrsta, vendar bi bilo pri morebitnih aktivnih varstvenih ukrepih za njeno ohranjanje smiselno čimbolj upoštevati ugotovljene tri geografsko-morfološke skupine.
Keywords: črnika, Quercus ilex, morfološka variabilnost, Slovenija, drevesni listi
Published in DiRROS: 12.09.2024; Views: 76; Downloads: 564
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4. In vitro evolution driven by epistasis reveals alternative cholesterol-specific binding motifs of perfringolysin OAleksandra Šakanović, Nace Kranjc, Neža Omersa, Saša Aden, Andreja Kežar, Matic Kisovec, Apolonija Bedina Zavec, Simon Caserman, Robert J. Gilbert, Marjetka Podobnik, Ana Crnković, Gregor Anderluh, 2024, original scientific article Published in DiRROS: 12.09.2024; Views: 54; Downloads: 492
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5. An anthology of contemporary ecotheology, philosophy and eco-justice practices : ECOTHEE volume 72023, scientific monograph Abstract: This book is the seventh volume in the ECOTHEE book series, which is published every two years and was first published in the field of ecumenical ecotheology in 2008, following the first ECOTHEE conference (ECOTHEE 08) held in Crete on the occasion of World Environment Day on June 5, 2008. Each ECOTHEE publication collects academic papers and statements by scientists, theologians, sociologists and researchers from different fields under the motto: “Religion and science can provide solutions to sustainability problems.” The articles selected in this seventh volume, ECOTHEE 22, continue the development of ecotheological resources on environmental ethics and sustainable solutions for the common oikos. This book follows the ECOTHEE goal and seeks to engage theology on key ecological concerns from a variety of religious traditions and perspectives. The emphasis is on theological and ethical implications of contributing to a sustainable ecological future. This publication is enriched with additional articles from the 5th SAPREJ conference on sustainable alternatives to poverty reduction and eco-justice and the roles, responsibilities and initiatives of religion, science and civil societies for ecological justice and biodiversity protection, held in Addis Ababa, Ethiopia, in May 2023. /// The present ECOTHEE 22 book is structured into the following sections: Introduction, Section 1: Towards Reconciliation and Justice for all Creation (Eco-ethical Theological and Philosophical Reflections), Section 2: Governance, Politics, Good Practices, and Critical Evaluations of Ecological (In)Justice. /// An “Anthology of Contemporary Ecotheology, Philosophy and Eco-Justice Practices” volume of ECOTHEE delivers chapters on contemporary insights into various religious, spiritual, philosophical reflections towards reconciliation and ecojustice for a sustainable future.
Published in DiRROS: 11.09.2024; Views: 70; Downloads: 1260
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7. Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastomaBernarda Majc, Anamarija Habič, Marta Malavolta, Miloš Vittori, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Alenka Matjašič, Andrej Zupan, Marija Skoblar Vidmar, Tamara Lah Turnšek, Aleksander Sadikov, Barbara Breznik, Metka Novak, 2024, original scientific article Abstract: Glioblastoma (GB) is the most common primary malignant brain tumor, characterized by resistance to therapy. Despite aggressive treatment options, GB remains an incurable disease. Invasiveness and heterogeneity are key GB features that cannot be studied in preclinical in vitro models. In this study, we investigated the effects of standard therapy using patient-derived GB organoids (GBOs). GBOs reflect the complexity and heterogeneity of the original tumor tissue. No significant effect on GBO viability or invasion was observed after irradiation and temozolomide treatment. E3 ubiquitin-protein ligase (MDM2), cyclin-dependent kinase inhibitor 1A (CDKN1A), and the serine/threonine kinases ATM and ATR were upregulated at the gene and protein levels after treatment. Our results show that the p53 pathway and DNA-damage response mechanisms were triggered, suggesting that GBOs recapitulate GB therapy resistance. GBOs thus provide a highly efficient platform to assess the specific responses of GB patients to therapy and to further explore therapy resistance.
Keywords: cellular physiology, cellular toxicology, in vitro toxicology including 3D culture, technical aspects of cell biology, cancer
Published in DiRROS: 09.09.2024; Views: 77; Downloads: 18
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8. The relationship between the inhalation bioaccessibility of potentially toxic elements in road dust from a heavily polluted industrial area and the source of their pollutionMarija Zupančič, Miloš Miler, Gorazd Žibret, 2024, original scientific article Abstract: One of the sources of chronic exposure to potentially toxic elements (PTE), especially in polluted environments, is the inhalation of resuspended road dust (RD). The aim of this study is to assess the inhalation bioaccessibility of PTE in RD from highly polluted environments from mining/smelting industries and traffic, and to identify any correlations between the bioaccessibility fraction of PTE and the physicochemical characteristics of the particles. RD from the studied area contains extremely high total concentrations of Cr, V, and Mn, which are likely due to pollution from the smelting industry. Additionally, elevated total concentrations of other elements associated with traffic emissions including Zn, Cu, Pb, Sb, and Sn were also measured. The bioaccessibility of PTE was assessed using two synthetic extraction solutions - Gamble's solution (GS) and Artificial Lysosomal Fluid (ALF). The majority of elements showed negligible bioaccessibility in GS. However, quite high inhalation bioaccessibility was observed for Zn, Pb, Sb, Cd, and Mn in the ALF solution, with a mean bioaccessible fraction of 49, 51.5, 41, 50, and 40% respectively. The highest bioavailable fraction was measured for Cd (97%) in a sample collected near a steel production facility and for Pb (95%) in a sample collected near the highway. These results indicate that increased mobility of the elements in inhaled particles occurs only in the case of phagocytosis. The lowest inhalation bioavailability was measured for Cr (mean is 3%). Differential individual particle analysis revealed that about 60% of phases, mostly major (Cr,Ti,V)-bearing metallic alloys, silicates, oxides and sulphides, are stable in ALF solution, while 40% of phases, mostly (Fe,Ca,Mn)-bearing oxides, silicates, sulphides, metals and metallic alloys originating from steel production, ferrochrome, ferrosilicon and vanadium production and from traffic emissions have been heavily corroded or completely dissolved. The study provides valuable information to further assess health hazards from various emission sources.
Keywords: coal mining, inhalation bioaccessibility, mining/smelting pollution, potentially toxic elements, road dust, traffic pollution
Published in DiRROS: 09.09.2024; Views: 99; Downloads: 3166
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9. Ultrasound-mediated spatial and temporal control of engineered cells in vivoFilip Ivanovski, Maja Meško, Tina Lebar, Marko Rupnik, Duško Lainšček, Miha Gradišek, Roman Jerala, Mojca Benčina, 2024, original scientific article Published in DiRROS: 09.09.2024; Views: 99; Downloads: 3911
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10. Precise design and construction of NiO-Ni heterostructures for active hydrogen evolution photocatalysisKamal Khaja Mohaideen, Rekha Narayan, Selvakannan Periasamy, Sašo Gyergyek, Stefan Popovic, Nejc Hodnik, Hsin-Chia Ho, Petar Djinović, Blaž Likozar, 2024, original scientific article Published in DiRROS: 09.09.2024; Views: 89; Downloads: 3843
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