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12. Effect of heat treatment on the microstructure and performance of high-velocity air-fuel sprayed WC-10Co4Cr coatingsXuedong Zhou, Haijun Liu, Jishi Zhang, Jinsheng Ji, Wensheng Zhao, Zhimin Zhang, Qiang Wang, Yong Xue, 2021, original scientific article Keywords: heat treatment, WC-10Co4Cr coatings, abrasion resistance, corrosion resistance Published in DiRROS: 06.05.2022; Views: 580; Downloads: 198 Link to file |
13. High-temperature deformation behavior andhot-processing map of 25CrMo4 axle steel based onfriction correctionKeran Liu, Yuanming Huo, Tao He, Cunlong Huo, Changyuan Jia, Xiangyang Du, Baoyu Wang, 2021, original scientific article Keywords: 25CrMo4 axle steel, hot-compression test, hot processing map, friction correction Published in DiRROS: 06.05.2022; Views: 572; Downloads: 171 Link to file |
14. Global homogenization of the structure and function in the soil microbiome of urban greenspacesManuel Delgado-Baquerizo, David J. Eldridge, Yu-Rong Liu, Blessing Sokoya, Jun-Tao Wang, Hang-Wei Hu, Ji-Zheng He, Felipe Bastida, José L. Moreno, Adebola R. Bamigboye, Tine Grebenc, Tina Unuk Nahberger, 2021, original scientific article Abstract: The structure and function of the soil microbiome of urban greenspaces remain largely undetermined. We conducted a global field survey in urban greenspaces and neighboring natural ecosystems across 56 cities from six continents, and found that urban soils are important hotspots for soil bacterial, protist and functional gene diversity, but support highly homogenized microbial communities worldwide. Urban greenspaces had a greater proportion of fast-growing bacteria, algae, amoebae, and fungal pathogens, but a lower proportion of ectomycorrhizal fungi than natural ecosystems. These urban ecosystems also showed higher proportions of genes associated with human pathogens, greenhouse gas emissions, faster nutrient cycling, and more intense abiotic stress than natural environments. City affluence, management practices, and climate were fundamental drivers of urban soil communities. Our work paves the way toward a more comprehensive global-scale perspective on urban greenspaces, which is integral to managing the health of these ecosystems and the well-being of human populations. Keywords: soil biodiversity, structural diversity, functional diversity, urban soils Published in DiRROS: 15.07.2021; Views: 1093; Downloads: 926 Full text (4,34 MB) This document has many files! More... |
15. Position of an international panel of lung cancer experts on the decision for expansion of approval for pembrolizumab in advanced non-small-cell lung cancer with a PD-L1 expression level of >= 1 by the USA Food and Drug AdministrationGiannis Mountzios, J. Remon, Silvia Novello, N. Blais, R. Califano, Tanja Čufer, Anne-Marie C. Dingemans, S. V. Liu, N. Peled, N. A. Pennell, 2019, other scientific articles Keywords: non-small cell lung carcinoma, drug therapy, KEYNOTE-024 trial, pemrolizumab, treatment Published in DiRROS: 21.09.2020; Views: 1403; Downloads: 921 Full text (106,29 KB) This document has many files! More... |
16. Heritable risk for severe anaphylaxis associated with increased [alpha]-tryptase-encoding germline copy number at TPSAB1Jonathan J. Lyons, Jack Chovanec, Michael P. O'Connell, Yihui Liu, Julij Šelb, Roberta Zanotti, Yun Bai, Jiwon Kim, Quang T. Le, Tom DiMaggio, Matija Rijavec, Peter Korošec, 2020, original scientific article Abstract: Background: An elevated basal serum tryptase level is associated with severe systemic anaphylaxis, most notably caused by Hymenoptera envenomation. Although clonal mast cell disease is the culprit in some individuals, it does not fully explain this clinical association. Objective: Our aim was to determine the prevalence and associated impact of tryptase genotypes on anaphylaxis in humans. Methods: Cohorts with systemic mastocytosis (SM) and venom as well as idiopathic anaphylaxis from referral centers in Italy, Slovenia, and the United States, underwent tryptase genotyping by droplet digital PCR. Associated anaphylaxis severity (Mueller scale) was subsequently examined. Healthy volunteers and controls with nonatopic disease were recruited and tryptase was genotyped by droplet digital PCR and in silico analysis of genome sequence, respectively. The effects of pooled and recombinant human tryptases, protease activated receptor 2 agonist and antagonist peptides, and a tryptase-neutralizing mAb on human umbilical vein endothelial cell permeability were assayed using a Transwell system. Results: Hereditary [alpha]-tryptasemia (H[alpha]T)--a genetic trait caused by increased [alpha]-tryptase-encoding Tryptase-[alpha]/[beta]1 (TPSAB1) copy number resulting in elevated BST level--was common in healthy individuals (5.6% [n = 7 of 125]) and controls with nonatopic disease (5.3% [n = 21 of 398]). H[alpha]T was associated with grade IV venom anaphylaxis (relative risk = 2.0; P < .05) and more prevalent in both idiopathic anaphylaxis (n = 8 of 47; [17%; P = .006]) and SM (n = 10 of 82 [12.2%; P = .03]) relative to the controls. Among patients with SM, concomitant H[alpha]T was associated with increased risk for systemic anaphylaxis (relative risk = 9.5; P = .007). In vitro, protease-activated receptor-2-dependent vascular permeability was induced by pooled mature tryptases but not [alpha]- or [beta]-tryptase homotetramers. Conclusions: Risk for severe anaphylaxis in humans is associated with inherited differences in [alpha]-tryptase-encoding copies at TPSAB1. Keywords: mastocytosis, venoms, hypersensitivity, anaphylaxis - diagnosis, mast cells, idiopathic anaphylaxis, mast cell activation, hereditary alpha-tryptasemia Published in DiRROS: 11.09.2020; Views: 2165; Downloads: 414 Link to file |
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18. In-situ regeneration of Au nanocatalysts by atmospheric-pressure air plasma : significant contribution of water vaporBin Zhu, Xiao-Song Li, Jing-Lin Liu, Jin-Bao Liu, Xiaobing Zhu, Ai-Min Zhu, 2015, original scientific article Keywords: Au catalyst, air plasma, in-situ regeneration, water vapor, CO oxidation Published in DiRROS: 07.04.2016; Views: 4547; Downloads: 1038 Link to full text |
19. In-situ plasma regeneration of deactivated Au/TiO [sub] 2 nanocatalysts during CO oxidation and effect of N [sub] 2 contentHong-Yu Fan, Chuan Shi, Xiao-Song Li, Shuo Zhang, Jing-Lin Liu, Ai-Min Zhu, 2012, original scientific article Keywords: gold catalyst, deactivation, plasma regeneration, N [sub] 2 content, CO oxidation Published in DiRROS: 07.04.2016; Views: 5908; Downloads: 883 Link to full text |