151. Priročnik iz onkološke zdravstvene nege in onkologije2000, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: diagnostika, zdravljenje, dejavniki tveganja, paliativna oskrba, psihoonkologija Published in DiRROS: 28.08.2020; Views: 1694; Downloads: 538 Full text (15,33 MB) |
152. Razstava citatov na Slovenskih dnevih sanitarnega inženistva 2018 z mednarodno udeležbo, Ljubljana, 17.-19. oktober 2018Aleš Krulec, Rok FINK, Andrej Ovca, Andreja KUKEC, Mojca JEVŠNIK, Željko LINŠAK, Marija POLJAK, Gregor JEREB, exhibition Keywords: sanitarno inženirstvo, sanitarni inženirji, slovenski dnevi sanitarnega inženirstva, 2018, razstava, mestni muzej ljubljana Published in DiRROS: 18.08.2020; Views: 2239; Downloads: 950 Full text (130,65 MB) |
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154. Genomic insights into the Mycobacterium kansasii complex : an updateTomasz Jagielski, Paulina Borówka, Zofia Bakuła, Jakub Lach, Błażej Marciniak, Anna Brzostek, Jarosław Dziadek, Mikołaj Dziurzyński, Lian Pennings, Jakobus van Ingen, Marija Žolnir-Dovč, Dominik Strapagiel, 2020, original scientific article Abstract: Only very recently, has it been proposed that the hitherto existing Mycobacteriumkansasii subtypes (I–VI) should be elevated, each, to a species rank. Consequently, the former M. kansasii subtypes have been denominated as Mycobacterium kansasii (former type I), Mycobacterium persicum (II), Mycobacterium pseudokansasii (III), Mycobacterium innocens (V), and Mycobacterium attenuatum (VI). The present work extends the recently published findings by using a three-pronged computational strategy, based on the alignment fraction-average nucleotide identity, genome-to-genome distance, and core-genome phylogeny, yet essentially independent and much larger sample, and thus delivers a more refined and complete picture of the M. kansasii complex. Furthermore, five canonical taxonomic markers were used, i.e., 16S rRNA, hsp65, rpoB, and tuf genes, as well as the 16S-23S rRNA intergenic spacer region (ITS). The three major methods produced highly concordant results, corroborating the view that each M. kansasii subtype does represent a distinct species. This work not only consolidates the position of five of the currently erected species, but also provides a description of the sixth one, i.e., Mycobacterium ostraviense sp. nov. to replace the former subtype IV. By showing a close genetic relatedness, amonophyletic origin, and overlapping phenotypes, our findings support the recognition of the M. kansasii complex (MKC), accommodating
all M. kansasii-derived species and Mycobacterium gastri. None of the most commonly used taxonomic markers was shown to accurately distinguish all the MKC species. Likewise, no species-specific phenotypic characteristics were found allowing for species differentiation within the complex, except the non-photochromogenicity of M. gastri.
To distinguish, most reliably, between the MKC species, and between M. kansasii and M. persicum in particular, whole-genome-based approaches should be applied. In the absence of clear differences in the distribution of the virulence-associated region of difference 1 genes among the M. kansasii-derived species, the pathogenic potential of each of these species can only be speculatively assessed based on their prevalence among the clinically relevant population. Large-scale molecular epidemiological studies are needed to provide a better understanding of the clinical significance and pathobiology of the MKC species. The results of the in vitro drug susceptibility profiling emphasize the priority of rifampicin administration in the treatment of MKC-induced infections, while
undermining the use of ethambutol, due to a high resistance to this drug. Keywords: Mycobacteriumkansasii complex, Mycobacteriumostraviense sp. nov., non-tuberculous mycobacteria
(NTM), whole genome sequencing, taxonomy Published in DiRROS: 31.07.2020; Views: 2009; Downloads: 1397 Full text (10,22 MB) This document has many files! More... |
155. Namnožitev osmerozobega in šesterozobega smrekovega lubadarja v Sloveniji v 2020Nikica Ogris, Marija Kolšek, 2020, professional article Keywords: Ips typographus, Pityogenes chalcographus, namnožitev, navadna smreka, Picea abies, osmerozobi smrekov lubadar, šesterozobi smrekov lubadar, lokacija, populacija, gostota, model, RITY-2, CHAPY-1 Published in DiRROS: 30.07.2020; Views: 1692; Downloads: 903 Link to full text This document has many files! More... |
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159. Ukrepi proti namnožitvi zapredkaric (Cephalcia spp.) na Riflovem vrhu pri Prevaljah v letu 2010Gorazd Mlinšek, Janko Mikeln, Franjo Štern, Marija Kolšek, 2010, professional article Keywords: zapredkarice, Pinus sylvestris L.Cephalcia spp., ukrepi, Prevalje, gozdovi, varstvo gozdov Published in DiRROS: 29.07.2020; Views: 1480; Downloads: 832 Link to full text This document has many files! More... |
160. Namnožitev molja macesnovih iglic (Coleophora laricella) v KE LitijaMaja Jurc, Dušan Jurc, Jože Horvat, Matej Zupančič, Marija Kolšek, Barbara Slabanja, 2011, professional article Keywords: molji, Coleophora laricella, macesen, iglice, Litija, gozdovi, varstvo gozdov Published in DiRROS: 29.07.2020; Views: 1552; Downloads: 737 Link to full text This document has many files! More... |