1. Breast cancer risk assessment and risk distribution in 3,491 Slovenian women invited for screening at the age of 50 : a population-based cross-sectional studyKatja Jarm, Vesna Zadnik, Mojca Birk, Miloš Vrhovec, Kristijana Hertl, Žan Klaneček, Andrej Studen, Cveto Šval, Mateja Krajc, 2023, original scientific article Abstract: Background. The evidence shows that risk-based strategy could be implemented to avoid unnecessary harm in mammography screening for breast cancer (BC) using age-only criterium. Our study aimed at identifying the uptake of Slovenian women to the BC risk assessment invitation and assessing the number of screening mammographies in case of risk-based screening.Patients and methods. A cross-sectional population-based study enrolled 11,898 women at the age of 50, invited to BC screening. The data on BC risk factors, including breast density from the first 3,491 study responders was col-lected and BC risk was assessed using the Tyrer-Cuzick algorithm (version 8) to classify women into risk groups (low, population, moderately increased, and high risk group). The number of screening mammographies according to risk stratification was simulated. Results. 57% (6,785) of women returned BC risk questionnaires. When stratifying 3,491 women into risk groups, 34.0% were assessed with low, 62.2% with population, 3.4% with moderately increased, and 0.4% with high 10-year BC risk. In the case of potential personalised screening, the number of screening mammographies would drop by 38.6% com-pared to the current screening policy. Conclusions. The study uptake showed the feasibility of risk assessment when inviting women to regular BC screen-ing. 3.8% of Slovenian women were recognised with higher than population 10-year BC risk. According to Slovenian BC guidelines they may be screened more often. Overall, personalised screening would decrease the number of screening mammographies in Slovenia. This information is to be considered when planning the pilot and assessing the feasibility of implementing population risk-based screening.
Keywords: breast cancer screening, personalised screening, risk assessment, mammography
Published in DiRROS: 25.07.2024; Views: 101; Downloads: 122
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2. Prepoznavanje ogroženosti za nastanek raka dojk na mamografskih slikahŽan Klaneček, Andrej Studen, Katja Jarm, Mateja Krajc, Miloš Vrhovec, Robert Jeraj, 2024, published professional conference contribution Abstract: Za prehod s populacijskega na personalizirano presejanje za raka dojk je v prvi vrsti potrebno natančno prepoznavanje ogroženosti za razvoj raka dojk. Standardni modeli, ki temeljijo na klasičnih značilkah, niso najbolj zanesljivi. Z razvojem umetne inteligence, predvsem na področju globokega učenja, se je izkazalo, da modeli, ki so naučeni na mamografskih slikah, dosegajo signifikantno boljše rezultate pri napovedovanju ogroženosti. Trenutno je najboljši model za napovedovanje ogroženosti MIRAI, ki je bil uspešno validiran na različnih populacijah. A vendar so rezultati še daleč od popolnih in možnosti za izboljšave je ogromno, predvsem na področju razširitve uporabnosti modela za različne proizvajalce mamografskih aparatov, vključevanja longitudinalnih sprememb in uporabe segmentiranih slik dojke.
Keywords: obvladovanje raka, presejalni programi, rak dojk, mamografija
Published in DiRROS: 06.06.2024; Views: 243; Downloads: 110
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5. Načrtovano komuniciranje med epidemijo covid-19 kot del aktivnosti, s katerimi smo uspeli ohraniti udeležbo žensk v programu DORA nad 70%Amela Duratović Konjević, Vesna Škrbec, Kristijana Hertl, Katja Jarm, Mateja Kurir-Borovčić, Miloš Vrhovec, Veronika Kutnar, Lucija Kolar, Katarina Torkar, Cveto Šval, 2022, published professional conference contribution abstract Keywords: onkologija, rak dojke, mediji
Published in DiRROS: 03.02.2023; Views: 554; Downloads: 137
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6. Odlično zadovoljstvo žensk s programom DORA : rezultati anonimne anketeMateja Kurir-Borovčić, Katja Jarm, Miloš Vrhovec, Veronika Kutnar, Lucija Kolar, Katarina Torkar, Vesna Škrbec, Cveto Šval, Kristijana Hertl, 2022, published professional conference contribution abstract Keywords: onkologija, rak dojke, kemoterapija
Published in DiRROS: 27.01.2023; Views: 538; Downloads: 148
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7. Programske smernice DORAMateja Kurir-Borovčić, Amela Duratović Konjević, Katja Jarm, Katarina Nagode, Maksimiljan Kadivec, Zvonka Kastelic, Veronika Kutnar, Andraž Perhavec, Barbara Skubic-Vengušt, Stanka Sabo, Špela Sitar, Stančka Suljić, Cveto Šval, Anastazija Šelih, Vesna Škrbec, Miloš Vrhovec, Sonja Tomšič, Katarina Torkar, Urban Zdešar, Kristijana Hertl, 2022, professional monograph Abstract: Državni presejalni program za raka dojk DORA (v nadaljevanju: program DORA) vabi ženske med 50. in 69. letom vsaki dve leti na presejanje z mamografijo, katerega cilj je zmanjšati umrljivost za rakom dojk v ciljni populaciji za 25 do 30 odstotkov. Nosilec programa DORA je Onkološki inštitut Ljubljana. Presejalno mamografijo opravlja 16 javnih zdravstvenih zavodov po Sloveniji na 20 digitalnih mamografih s kadri, ki so za svoje delo posebej usposobljeni. Dodatno diagnostiko in zdravljenje raka dojk, odkritega v presejanju, izvajata presejalno-diagnostična centra na Onkološkem inštitutu Ljubljana in v Univerzitetnem kliničnem centru Maribor. Te programske smernice opredeljujejo presejalno politiko programa DORA, postopek obravnave žensk, organizacijo in dejavnosti programa DORA. Delijo se na upravljalske, zdravstvene in druge storitve. Sestavni del teh programskih smernic je tudi določitev strokovnega nadzora, ki se opravlja v presejalnem programu, ter podrobnejši Standardni operativni postopki (SOP) delovanja programa DORA. Sestavni del tega dokumenta so tudi Protokoli in priloge.
Keywords: rak dojke, programske smernice, presejalni programi, svetovanje
Published in DiRROS: 08.12.2022; Views: 805; Downloads: 333
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