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31.
Environmental enrichment through virtual reality as multisensory stimulation to mitigate the negative effects of prolonged bed rest
Luka Šlosar, Manca Peskar, Rado Pišot, Uroš Marušič, 2023, review article

Abstract: Prolonged bed rest causes a multitude of deleterious physiological changes in the human body that require interventions even during immobilization to prevent or minimize these negative effects. In addition to other interventions such as physical and nutritional therapy, non-physical interventions such as cognitive training, motor imagery, and action observation have demonstrated efficacy in mitigating or improving not only cognitive but also motor outcomes in bedridden patients. Recent technological advances have opened new opportunities to implement such non-physical interventions in semi- or fully-immersive environments to enable the development of bed rest countermeasures. Extended Reality (XR), which covers augmented reality (AR), mixed reality (MR), and virtual reality (VR), can enhance the training process by further engaging the kinesthetic, visual, and auditory senses. XR-based enriched environments offer a promising research avenue to investigate the effects of multisensory stimulation on motor rehabilitation and to counteract dysfunctional brain mechanisms that occur during prolonged bed rest. This review discussed the use of enriched environment applications in bedridden patients as a promising tool to improve patient rehabilitation outcomes and suggested their integration into existing treatment protocols to improve patient care. Finally, the neurobiological mechanisms associated with the positive cognitive and motor effects of an enriched environment are highlighted.
Keywords: physical inactivity, bed rest, nonphysical interventions, virtual reality
Published in DiRROS: 11.09.2023; Views: 389; Downloads: 195
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33.
Effects of digital-based interventions on muscular strength in adults : a systematic review, meta-analysis and meta-regression of randomized controlled trials with quality of evidence assessment
Armin Paravlić, Luka Šlosar, Ensar Abazović, Uroš Marušič, 2023, review article

Abstract: Background: In the last three decades, both medical and sports science professionals have recognized the considerable potential of digital-based interventions (DBI) to enhance the health-related outcomes of their practitioners.Objectives: This study aimed to investigate the effectiveness and potential moderators of DBI on measures of muscular strength.Methods: Six databases (PubMed/MEDLINE, Web of Science, SportDiscus, Embase, Cochrane Register of Controlled Trials and Google Scholar) were searched for eligible studies up to June 2022. The GRADE, PEDRO, and TIDieR checklists were used to assess the quality of evidence, methodology, and completeness of intervention descriptions, respectively.Results: A total of 56 studies were included in the meta-analysis (n = 2346), and participants were classified as healthy (n = 918), stroke survivors (n = 572), diagnosed with other neurological disorders (n = 683), and frail (n = 173). The DBI showed a small effect (standardized mean difference [SMD] = 0.28, 95% CI 0.21 to 0.31; p < 0.001) on strength, regardless of the type of intervention, control group, or tested body part. More specifically, while splitting the studies into different subgroups, a meta-analysis of 19 studies (n = 918) showed a small effect (SMD = 0.38, 95% CI 0.12 to 0.63; p = 0.003) on strength in the asymptomatic population. Similarly, small but positive effects of DBI were observed for stroke survivors (SMD = 0.34, 95% CI 0.13 to 0.56; p = 0.002), patients diagnosed with other neurological disorders (SMD = 0.17, 95% CI 0.03 to 0.32; p = 0.021), and the frail population (SMD = 0.25, 95% CI 0.0 to 0.5; p = 0.051). Sub-group analysis and meta-regression revealed that neither variable modified the effects of the DBI on measures of strength.Conclusions: Overall, DBI may serve as an effective method to improve measures of strength in adults, regardless of their health status as well as the type of digital device, the presence of human-computer interaction, and the age of participants. In addition, the DBI was found to be more effective than traditional training or rehabilitation methods.
Keywords: cognitive training, physical function, strength, neurodegenerative disorders, older adults
Published in DiRROS: 07.08.2023; Views: 458; Downloads: 229
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34.
Makroekonomski učinki proizvodnje in predelave lesa listavcev
Domen Arnič, Peter Prislan, Luka Juvančič, 2023, original scientific article

Abstract: As far as the utilization of the value-added potential of hardwood assortments is concerned, we have considerable reserves in Slovenia. These could be exploited mainly by increasing the economic use of roundwood in Slovenia and by developing more technologically advanced processing methods for roundwood. The aim of this paper is to assess the untapped potential of the forest-wood chain in Slovenia using input-output models, focusing on the use of hardwood. For the whole forest-wood chain, we assessed the existing situation and tested five scenarios for the improvement of the forest-wood chain in Slovenia. We developed a national input-output model to evaluate possible scenarios for the future development of the wood-based bioeconomy. The results of scenario analysis of the input-output model show that the Slovenian wood-based bioeconomy can achieve up to 20% higher production value, a 24% increase in employment and 19% increase in household income in the future through restructuring of economic activities. In the paper, we discuss how upgrading the forestry and wood-processing industry (according to the defined scenarios) could be achieved by increasing the processing capacity of hardwoods and provide recommendations for decision makers.
Keywords: forest- and wood-based bioeconomy, hardwoods utilization, input-output models, wood processing industry, scenario analysis, mobilization of hardwoods
Published in DiRROS: 03.08.2023; Views: 400; Downloads: 211
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35.
Analiza kakovostne strukture okroglega lesa listavcev
Luka Krajnc, Domen Arnič, Peter Prislan, 2023, original scientific article

Abstract: The research presented in this study addressed the distribution of volume across different log grades in three hardwood species: European beech (Fagus sylvatica L.), sycamore maple (Acer pseudoplatanus L.) and English oak (Quercus robur L.). Standing trees were selected, marked, and measured. Afterwards the trees were felled and bucked into assortments according to national legislation regarding assortment grades and requirements for each assortment grade. Each individual assortment was measured and classified into one of the national log quality grades. Proportions of log volume with different grades within individual tree volumes were calculated and presented in this study. Differences were found in log grade volume distribution between different species and diameter classes. By following the national grading system for assortments, between 40% and 50% of total volume will be usable assortments in hardwoods
Keywords: logs, hardwoods, volume, quality, log grading
Published in DiRROS: 03.08.2023; Views: 373; Downloads: 209
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36.
Priporočila za obravnavo bolnikov s pljučnim rakom
Martina Vrankar, Nina Boc, Izidor Kern, Aleš Rozman, Karmen Stanič, Tomaž Štupnik, Mojca Unk, Maja Ebert Moltara, Vesna Zadnik, Katja Adamič, Jernej Benedik, Marko Bitenc, Jasna But-Hadžić, Anton Crnjac, Marina Čakš, Dominik Časar, Eva Ćirić, Tanja Čufer, Ana Demšar, Rok Devjak, Goran Gačevski, Marta Globočnik Kukovica, Kristina Gornik-Kramberger, Maja Ivanetič Pantar, Marija Ivanović, Urška Janžič, Staša Jelerčič, Veronika Kloboves-Prevodnik, Mile Kovačević, Luka Ležaič, Mateja Marc-Malovrh, Katja Mohorčič, Loredana Mrak, Igor Požek, Nina Turnšek, Bogdan Vidmar, Dušanka Vidovič, Gregor Vlačić, Ana Lina Vodušek, Rok Zbačnik, Ivana Žagar, 2023, professional article

Abstract: Leta 2019 so bila objavljena Priporočila za obravnavo bolnikov s pljučnim rakom, ki so v slovenski prostor vnesla prepotrebno poenotenje diagnostike in zdravljenja z namenom izboljšanja preživetja bolnikov s pljučnim rakom. Posodobitev Priporočil tri leta po izidu izvirnika prinaša največ novosti v poglavju o sistemskem zdravljenju bolnikov s pljučnim rakom. To kaže na izjemen napredek na področju razumevanja onkogeneze in biologije pljučnega raka ter s tem razvoja novih zdravil. Breme pljučnega raka ostaja veliko, saj je pljučni rak pri nas in v svetu še vedno najpogostejši vzrok smrti zaradi raka. Za vsako peto smrt zaradi raka je odgovoren pljučni rak. Skoraj tretjina bolnikov s pljučnim rakom ne prejme specifičnega onkološkega zdravljenja, bodisi zaradi slabega stanja zmogljivosti, spremljajočih bolezni ali obsega bolezni. Polovica bolnikov ima ob diagnozi razsejano bolezen, zaradi česar izboljšanje preživetja z malimi koraki sledi napredku v zdravljenju bolnikov s pljučnim rakom. Ti podatki nas opominjajo, da se bomo morali za velike premike v obravnavi bolnikov s pljučnim rakom lotiti drugačnih pristopov. Kot najbolj obetavno se ponuja zgodnje odkrivanje bolezni, ko so možnosti ozdravitve pljučnega raka najboljše. Zapisana Priporočila so usmeritev za obravnavo bolnikov s pljučnim rakom. Le s sodobnim multidisciplinarnim pristopom obravnave lahko bolniku ponudimo zdravljenje, ki mu omogoča najboljši izhod prognostično neugodne bolezni.
Keywords: pljučni rak, priporočila
Published in DiRROS: 27.07.2023; Views: 514; Downloads: 183
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37.
Upper Miocene ostracods from the Krško Basin, SE Slovenia
Miha Marinšek, Valentina Hajek-Tadesse, Marijan Poljak, Tea Kolar-Jurkovšek, Luka Gale, 2023, original scientific article

Abstract: The purpose of this study was to identify the ostracod assemblage from a 43 m thick section of the Bizeljsko Formation, which constitutes the middle part of the Upper Miocene Posavje Group. The succession comprises sandstone, siltstone, and marlstone, deposited in a delta front environment. The determined ostracods belong to the families Cyprididae, Cytheridae, Darwinulidae, and Loxoconchidae. In total, 30 species were identified. Additionally, 8 morphotypes were determined at the genus level. The most common genera are Candona, Hemicytheria, and Cyprideis. The assemblage belongs to the Caspiocypris labiata subzone from the upper Pannonian. The ostracod assemblage from the Krško Basin is similar in species composition to Pannonian ostracod assemblages from Croatia and Serbia.
Keywords: Lake Pannon, Bizeljsko Formation, Pannonian, biostratigraphy, palaeoenvironment
Published in DiRROS: 27.07.2023; Views: 350; Downloads: 158
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38.
Functional characteristics and subjective disease perception in patients with COVID-19 two months after hospital discharge
Kaja Teraž, Boštjan Šimunič, Manca Peskar, Uroš Marušič, Saša Pišot, Luka Šlosar, Mladen Gasparini, Rado Pišot, 2023, original scientific article

Abstract: Introduction: Although early inpatient and post-hospital rehabilitation is recognized as necessary, not all COVID-19 patients have access to rehabilitation. There are no published reports in the literature that investigate the outcomes of patients who do not receive rehabilitation after COVID-19. Our aim was to evaluate possible improvements in determinate functional and psychological parameters in COVID19 patients two months after their hospital discharge. Methods: On both time points various motor, cognitive, and clinical measurements such as body composition, tensiomyography, blood pressure, spirometry, grip strength test, Timed Up and Go test, gait speed, 30-second chair-stand test, and Montreal Cognitive Assessment, were performed. Additionally, questionnaires such as the SARC-CalF test, Edmonton frail scale, International Physical Activity questionnaire andThe Mediterranean Lifestyle index were conducted to assess lifestyle characteristics. Results: A total of 39 patients (87.2% male; mean age of 59.1 ± 10.3 years), who were hospitalized due to COVID-19 at the Izola General Hospital (IGH), Slovenia between December 2020 and April 2021, were included. Patients were assessed at two time points (T1 and T2): T1 was taken after receiving a negative COVID-19 test and T2 was taken two months after T1. After two months of self-rehabilitation, we have detected a BMI increase (p < .001), fat free mass increase (p < .001), better Edmonton frail scale (p < .001), SARC-CalF score (p = .014) and MoCA score (p = .014). There were no detected changes in lifestyle habits nor in physical performance tests. Discussion: It is already known that COVID-19 has long-term negative consequences regardless of the stage of the disease. Our findings support the notion that patients cannot fully regain all their functions within a two-month period without receiving structured or supervised rehabilitation. Therefore, it is crucial to offer patients comprehensive and structured rehabilitation that incorporates clinical, cognitive, and motor exercises.
Keywords: pandemics, coronavirus, functional improvement, hospital stay, health perception
Published in DiRROS: 26.07.2023; Views: 398; Downloads: 197
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39.
Corrosion protection of brown and green patinated bronze
Tadeja Kosec, Živa Novak, Erika Švara Fabjan, Luka Škrlep, Andrijana Sever Škapin, Polonca Ropret, 2021, original scientific article

Abstract: Bronze surfaces, whether bare or patinated, tend to change when exposed to an outdoor atmosphere. Art made of bronze which is exposed to the outdoors is usually artificially patinated. This patina changes when exposed to rain, especially in polluted rain, where sulphuric, nitric or carbonic acids are present. In order to gain optimal protection of different patinas and consequently reduce the patina changes over the time different protection systems were developed, tested and tailored. Three types of patina (brown, green sulphate, and green persulphate) were prepared, protected and subsequently studied. The protections were based on two coatings (i) fluoropolymer based coating (FA-MS) and (ii) newly developed fluoropolymer based coating with addition of mercaptopropyl groups, named as alternative fluoropolymer coating (FA-MS-SH). Both the pure patinas applied on bronze surfaces as well as the bare bronze were electrochemically tested, first unprotected and then following the application of two different types of protection. After the protection was applied to the pa- tinas, the change in colour was defined. Different techniques were utilised in order to define the morphology and structure of the patinas, as well as the change in colour following application of the coating. It was shown that a fluoropolymer coating (FA-MS) provided the most efficient protection to bare bronze and the sulphate patina, while a newly proposed alternative fluoropolymer coating (FA-MS-SH) offered good protection to bare and brown patinated bronze. A mechanism for the protection of bare and patinated bronze was suggested.
Keywords: bronze, patina, protection
Published in DiRROS: 17.07.2023; Views: 385; Downloads: 208
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40.
Effects of COVID-19 on cognition and mood after hospitalization and at 2-month follow-up
Manca Peskar, Boštjan Šimunič, Luka Šlosar, Saša Pišot, Kaja Teraž, Mladen Gasparini, Rado Pišot, Uroš Marušič, 2023, original scientific article

Abstract: A plethora of evidence links SARS-CoV-2 infection with concomitant cognitive dysfunction, which often persists weeks to months after the acute stages of illness and affects executive function, attention, memory, orientation, and movement control. It remains largely unclear which conditions or factors exacerbate the recovery. In a cohort of N=37 Slovenian patients (5 females, aged M = 58, SD = 10.7 years) that were hospitalized because of COVID-19, the cognitive function and mood states were assessed immediately after discharge and 2-months later to investigate the early post-COVID recovery changes. We assessed the global Montreal Cognitive Assessment (MoCA), Simple and Choice Reaction Times, executive functions (Trail-Making Test – TMT-A and TMT-B), short-term memory (Auditory Verbal Learning Test – AVLT), and visuospatial memory. We monitored depressive and anxiety symptoms and applied general self-efficacy and cognitive complaints questionnaires. Our results showed a global cognitive impairment (MoCA, Z = 332.5; p = 0.012), poorer performance on executive functions (TMT-A, Z = 188; p = 0.014; and TMT-B, Z = 185; p = 0.012), verbal memory (AVLT, F = 33.4; p < 0.001), and delayed recall (AVLT7, F = 17.1; p < 0.001), and higher depressive (Z = 145; p = 0.015) and anxiety (Z = 141; p = 0.003) symptoms after hospital discharge compared to 2-month follow-up, indicating that SARS-CoV-2 may transiently impair cognitive function and adversely affect the mood. No improvement in MoCA was observed in 40.5% of the patients at follow-up, indicating possible long-term effects of COVID-19 on global cognitive performance. Medical comorbidities (p = 0.035) significantly predicted the change in MoCA score over time, while fat mass (FM, p = 0.518), Mediterranean diet index (p = .0.944), and Florida Cognitive Activities Score (p = 0.927) did not. These results suggest that the patients’ medical comorbidities at the time of SARS-CoV-2 infection could importantly contribute to the acute impairment of cognitive function and stress the importance of systemic implementation of countermeasures to limit the negative consequences on public health.
Keywords: Coronavirus, recovery, acute respiratory sindrom, cognitive functions, cognitive impairment, MOCA, trail-making test
Published in DiRROS: 01.06.2023; Views: 579; Downloads: 258
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