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22. Stereotaktično obsevanje : novi izzivi zdravljenja v radioterapiji : [strokovno srečanje : elektronski zbornik prispevkov : v Ljubljani, 27.11. 2020]2020, professional monograph Abstract: Stereotaktično obsevanje, tehnika obsevanja, s katero dovedemo visoko obsevalno dozo na manjšo tarčo kjerkoli v telesu, predstavlja eno izmed možnosti radikalnega zdravljenja nekaterih tumorjev, zasevkov ali celo benignih stanj. Stereotaktično obsevanje je neinvazivno, stroški zdravljenja so nizki, bolnikom omogoča hitrejšo vrnitev v domače oziroma delovno okolje, ne poslabša kvalitete življenja in ima nizko stopnjo akutne morbiditete in mortalitete. V skrbnih radioterapevtskih postopkih, od izbora primernih bolnikov za stereotaktično obsevanje, priprave na obsevanje in izdelave obsevalnega načrta, kontrole kvalitete obsevanja, izvedbe obsevanja na linearnem pospeševalniku ter bolnikove oskrbe, sodelujemo zdravniki onkologi radioterapevti, radiologi, medicinski fiziki, dozimetristi, radiološki inženirji, medicinske sestre in zdravstveni tehniki. Skupen cilj naše timske obravnave in naporov medicinskega osebja je predvsem izboljšanje rezultatov zdravljenja ter ohranitev oziroma izboljšanje kvalitete življenja vsakega posameznega bolnika. Veliko pozornosti posvečamu tudi zmanjševanju tveganja za pojav kratkoročnih ali dolgoročnih neželenih učinkov stereotaktičnega obsevanja.
Keywords: radioterapija, elektronske knjige
Published in DiRROS: 08.12.2020; Views: 2257; Downloads: 563
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23. Cabbage and fermented vegetables : from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19Jean Bousquet, Josep M. Antò i Boquè, Wienczyslawa Czarlewski, Tari Haahtela, Susana C. Fonseca, Guido Laccarino, Hubert Blain, Alain Vidal, Aziz Sheikh, Cezmi A. Akdis, Torsten Zuberbier, Samo Kreft, Klemen Jenko, Maja Jošt, Peter Kopač, Mitja Košnik, Karmen Kramer Vrščaj, Bojan Madjar, Davor Plavec, Tanja Soklič, Jure Urbančič, Mihaela Zidarn, 2020, original scientific article Abstract: Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage were associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin converting enzyme 2 (ACE2). As a result of SARS-Cov-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1R) axis associated with oxidative stress. This leads to insulin resistanceas well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block the AT1R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are given: Kimchi in Korea, westernized foods and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects helpful in mitigating COVID-19 severity.
Keywords: COVID-19, diet, sulforaphane, Lactobacillus, Angiotensin converting enzyme 2, kimchi, cabbage, fermented vegetable
Published in DiRROS: 07.10.2020; Views: 1511; Downloads: 371
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24. Is diet partly responsible for differences in COVID-19 death rates between and within countries? : protocol for a systematic reviewJean Bousquet, Josep M. Antò i Boquè, Guido Laccarino, Wienczyslawa Czarlewski, Tari Haahtela, Aram Anto, Cezmi A. Akdis, Hubert Blain, Giorgio Walter Canonica, Karmen Kramer Vrščaj, Tari Haahtela, Mitja Košnik, Anja Koren, Peter Kopač, Maja Jošt, Samo Kreft, Klemen Jenko, Bojan Madjar, Davor Plavec, Tanja Soklič, Jure Urbančič, Mihaela Zidarn, 2020, review article Abstract: Reported COVID-19 deaths in Germany are relatively low as compared to many European countries. Among the several explanations proposed, an early and large testing of the population was put forward. Most current debates on COVID-19 focus on the differences among countries, but little attention has been given to regional differences and diet. The low-death rate European countries (e.g. Austria, Baltic States, Czech Republic, Finland, Norway, Poland, Slovakia) have used different quarantine and/or confinement times and methods and none have performed as many early tests as Germany. Among other factors that may be significant are the dietary habits. It seems that some foods largely used in these countries may reduce angiotensin-converting enzyme activity or are anti-oxidants. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.
Keywords: coronavirus, diet, angiotensin-converting enzyme, antioxidant, food
Published in DiRROS: 09.09.2020; Views: 1640; Downloads: 1259
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25. Ne-Hodgkinovi limfomi (NHL) - klinična slika, diagnostika in zdravljenjeMarija Fidler-Jenko, Gabrijela Petrič-Grabnar, Rudi Snoj, 1994, published professional conference contribution Keywords: onkologija, rak (medicina), ne-Hodgkinov limfom, diagnostika, zdravljenje
Published in DiRROS: 17.09.2019; Views: 2066; Downloads: 644
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28. Rezultati kontrole prireje mleka in mesa : Slovenija 2013Mija Sadar, Janez Jenko, Janez Jeretina, Betka Logar, Tomaž Perpar, Peter Podgoršek, 2014, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: govedoreja, prireja, mleko, 110 let, meso, kontrola, rezultati, 2013, Slovenija, poročila
Published in DiRROS: 03.06.2015; Views: 6420; Downloads: 1268
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