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2. Primary pulmonary choricarcinomaŽiga Snoj, Igor Kocijančič, Erik Škof, 2017, review article Abstract: The aim of the study was to establish whether there are different clinical entities of primary pulmonary choriocarcinoma (PPC) that deserve different diagnostic approach and the most optimal treatment. Patients and methods. A systematic review with PubMed search was conducted to identify studies that reported cases of PPC. The eligibility criteria were histological diagnosis of pulmonary choriocarcinoma and thorough examination of the reproductive organs to exclude potential primary choriocarcinoma in the gonads. Furthermore, to illustrate the review we additionally present a patient referred at our institution. Results. 55 cases (17 men) were included in the review with a median age of 34 years. Women with the history of gestational event showed better survival outcome than women without the history of gestational event. Patients treated with combined modality treatment (surgery and chemotherapy) survived longer than the patients without combined modality treatment. Furthermore, multivariate analysis of prognostic factors showed that the combined modality treatment had independent prognostic significance. Size of the tumour showed significant prognostic influence in univariate and multivariate analysis. Conclusions. PPC is an extreme rarity with variable clinical characteristics and outcome. It is important to capture and treat patients in the early stages of the disease. Women with the history of gestational event may show better survival, therefore genetic examination could help us to predict patient%s prognosis. Surgery followed by adjuvant chemotherapy appears to represent the best treatment for PPC.
Keywords: choriocarcinoma, gestational event, pulmonary tumor, primary horiokarcinom
Published in DiRROS: 10.05.2024; Views: 91; Downloads: 32
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5. NutriGreen image dataset : a collection of annotated nutrition, organic, and vegan food productsJan Drole, Igor Pravst, Tome Eftimov, Barbara Koroušić-Seljak, 2024, original scientific article Abstract: In this research, we introduce the NutriGreen dataset, which is a collection of images representing branded food products aimed for training segmentation models for detecting various labels on food packaging. Each image in the dataset comes with three distinct labels: one indicating its nutritional quality using the Nutri-Score, another denoting whether it is vegan or vegetarian origin with the V-label, and a third displaying the EU organic certification (BIO) logo.
Published in DiRROS: 23.04.2024; Views: 125; Downloads: 43
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6. Segmentation of hepatic vessels from MRI images for planning of electroporation-based treatments in the liverMarija Marčan, Denis Pavliha, Maja Marolt-Mušič, Igor Fučkan, Ratko Magjarević, Damijan Miklavčič, 2014, original scientific article Keywords: electrochemotherapy, non-thermal irreversible electroporation, treatment planning, hepatic vessel segmentation, non-invasive tumor treatments, MRI of liver
Published in DiRROS: 16.04.2024; Views: 153; Downloads: 69
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7. Depth of SCUBA diving affects cardiac autonomic nervous systemMarina Vulić, Branislav Milovanovic, Ante Obad, Duška Glavaš, Igor Glavičič, Damir Zubac, Maja Valic, Zoran Valić, 2024, review article Abstract: The present study investigated the influence of SCUBA dives with compressed air at depths of 10 and 20 m on ECG-derived HRV parameters in apparently healthy individuals. We hypothesized that cardiac sympathetic activity (measured by HRV parameters) adapts proportionally to diving depth, and that both time- and frequency-domain parameters are sensitive enough to track changes in cardiac ANS function during diving activities and subsequently during the recovery period. Eleven healthy middle-aged recreational divers (nine men and two women, age 43 ± 8, all nonsmokers) volunteered to participate in the present study. The participants (all open-circuit divers) were equipped with dry suits and ECG Holter devices and were later randomly assigned to dive pairs and depths (10 m vs. 20 m), and each participant served as his or her own control. No interaction effects (diving depth x time epoch) were found for the most commonly used HRV markers. More precisely, in response to two different diving protocols, a significant post hoc effect of time was observed for HR and SDNN, as these parameters transiently decreased during the dives and returned to baseline after ascent (p < 0.001). The ULF, VLF (p < 0.003), TP, and LF parameters decreased significantly during the dives, while HF significantly increased (p < 0.003). SCUBA diving apparently challenges the cardiac ANS, even in healthy individuals. The observed changes reveal possible underwater methods of influencing the parasympathetic activity of the heart depending on the depth of the dive. These results identify autonomic nervous system markers to track the cardiovascular risk related to diving and point to the possibility of tracking cardiovascular system benefits during underwater activities in selected patients
Keywords: autonomic nervous system, diving, parasympathicus, cardiovascular risk
Published in DiRROS: 09.04.2024; Views: 136; Downloads: 53
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9. Human tooth pulp anatomy visualization by 3D magnetic resonance microscopyDušan Šušterčič, Igor Serša, 2012, original scientific article Abstract: Background. Precise assessment of dental pulp anatomy is of an extreme importance for a successful endodontic treatment. As standard radiographs of teeth provide very limited information on dental pulp anatomy, more capable methods are highly appreciated. One of these is 3D magnetic resonance (MR) microscopy of which diagnostic capabilities in terms of a better dental pulp anatomy assessment were evaluated in the study. Materials and methods. Twenty extracted human teeth were scanned on a 2.35 T MRI system for MR microscopy using the 3D spin-echo method that enabled image acquisition with isotropic resolution of 100 m. The 3D images were then post processed by ImageJ program(NIH) to obtain advanced volume rendered views of dental pulps. Results. MR microscopy at 2.35 T provided accurate data on dental pulp anatomyin vitro. The data were presented as a sequence of thin 2D slices through the pulp in various orientations or as volume rendered 3D images reconstructed form arbitrary view-points. Sequential 2D images enabled only anapproximate assessment of the pulp, while volume rendered 3D images were more precise in visualization of pulp anatomy and clearly showed pulp diverticles, number of pulp canals and root canal anastomosis. Conclusions. This in vitro study demonstrated that MR microscopy could provide very accurate 3D visualization of dental pulp anatomy. A possible future application of the method in vivo may be of a great importance for the endodontic treatment.
Published in DiRROS: 21.03.2024; Views: 140; Downloads: 33
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10. Meshless simulation of a macrosegregation benchmark considering the solid motionViktor Govže, Igor Vušanović, Božidar Šarler, 2023, published scientific conference contribution Abstract: We have extended the existing two-dimensional rigid solid phase benchmark for binary substance with the solid phase motion in the present paper. Incompressible laminar Newtonian flow is assumed, and a standard mixture formulation is used for the mass, momentum, energy, and solute transport. A coherency solid motion model accounts for the free-floating grains, assuming that the solid velocity is proportional to the mixture velocity and the liquid fraction. The lever rule is used to describe the mass fractions of the phases. A two-dimensional benchmark is solved using the semi-implicit meshless diffuse approximate method with an adaptive subdomain upwinding strategy. The results of the meshless method are compared to the finite volume method results with a reasonable agreement. The new benchmark results show that the solid motion has an essential effect on the macrosegregation pattern.
Keywords: solidification, meshless methods, grain motion, benchmarks
Published in DiRROS: 21.03.2024; Views: 180; Downloads: 82
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