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Abstract: Background. Slovenia has a high burden of head and neck cancer. Patients are mostly treated with surgery followed by radiation therapy. Advanced surgical and prosthodontic techniques have expanded the rehabilitation options. The aim of the study was to review the outcome of implant-prosthetic treatment after radiation therapy. Patients and methods. Twenty irradiated head and neck cancer patients who received a removable implantsupported denture at the University Medical Centre Ljubljana were included in the study. Kaplan-Meier survival analysis, Cox proportional hazard models and logistic regression were used to assess the implant survival and success rate. Results. Twenty patients had 100 implants inserted. The estimated implant survival rate was 96% after 1 year and 87% after 5 years. Failures were mostly observed before loading (91.2%). Implants inserted in the transplanted bone were significantly more likely to fail. Out of 89 implants supporting the dentures, 79 implants (88.7%) were successful, meaning that they were functionally loaded and exhibited no pain, radiolucency or progressive bone loss. Prosthetic treatment was significantly less successful in older patients. The attachment system and the number of implants did not have a statistically significant influence on the success rate. Conclusions. Implant-supported dentures have been shown to be a reliable treatment modality after head and neck cancer surgery and radiation therapy. Possible early failures should be communicated with the patients.
Keywords: head and neck cancer, radiation therapy, dental implants
Published in DiRROS: 03.06.2024; Views: 71; Downloads: 32
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Abstract: Two stratigraphically well constrained (by ammonites and conodonts) coleoid remains have been recorded from the Triassic (Anisian) dark-grey organodetritic limestones (Ráztoka Limestone) of Western Carpathians (Hronic Nappe). The limestones deposited at the periphery of a former carbonate platform. It yields a highly diverse cephalopod fauna including nautiloids (2 taxa), ammonoids (7 taxa) and indetermined aulacoceratids. Two unusual coleoid specimens are referred to genus Mojsisovicsteuthis (M. boeckhi) and probably to a new taxon (described as Breviconoteuthis aff. breviconus herein) possessing similar morphological features of genus Breviconoteuthis (Phragmoteuthida) and/or Zugmontites. Based on index ammonites and conodonts, both records are of the uppermost Trinodosus through the lowermost Reitzi zones (Anisian—lower Illyrian). While the genus Mojsisovicsteuthis has been widely dispersed (however its records are rare), the occurrence of Breviconoteuthis and Zugmontites is strictly limited to the Alpine-Carpathian region. Comparing with the holotype and additional specimens stored in the Hungarian Natural History Museum, the overal shell of Mojsisovicsteuthis and its size has been reconstructed. Its relationship to aulacoceratids and phragmoteuthids is briefly discussed. Geochemical record (n-alkanes from the bulk rock) provided a relevant signal of the existence of algal meadows.
Keywords: Cephalopods, Conodonts, Anisian, Palaeoenvironment
Published in DiRROS: 21.05.2024; Views: 119; Downloads: 161
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Keywords: intracranial aneurysms, enovascular embolization, perianeurysmal oedema, hypertension
Published in DiRROS: 16.04.2024; Views: 147; Downloads: 35
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Keywords: long-time tempering, strengthening, Cu precipitate, medium-C steel, mechanical properties
Published in DiRROS: 02.02.2024; Views: 300; Downloads: 106
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Abstract: The aim of this paper is to establish the current situation in the field of legislation on the protection of experimental animals in Slovenia. The protection of experimental animals has been regulated by the provisions of theProtection of Animals Act.1 On the basis of this act, the Instructions on Conditions for the Issuing of Authorisations for Experiments on Animals for Scientific and Research Purposes2 and the Rules on the Ethics Commission for Experiments on Animals 3 have been used. The basic protection of experimental animals is provided for by a system of permits for experiments on animals. Permits for experiments on animals are granted by the administrative authorities responsible for veterinary medicine in cases where experiments areurgently required for medical, veterinary medical, or scientific and research purposes and the results are expected to produce important new knowledge, or when the suffering of animals is ethically acceptable in comparison with what the experiment is expected to achieve; where, in cases ofbasic research, experimental aims cannot be achieved by any other method or procedure, the experiment is performed on the minimum possible number of animals of the lowest neurophysiological sensitivity and a method is used thatcauses the minimum level of suffering, pain or lasting harm. Staff involved in the execution of experiments or in the care and nursing of animals, the premises for the accommodation or rearing and provision of animals, and the installations and devices used must all comply with the set conditions. (Abstract truncated at 2000 characters)
Published in DiRROS: 26.01.2024; Views: 215; Downloads: 47
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