51. |
52. First record of the bryozoan Tricellaria inopinata (dʼHondt & Occhipinti Ambrogi, 1985) from the Slovenian seaAna Fortič, Borut Mavrič, 2018, other scientific articles Abstract: In this paper we present the first record of Tricellaria inopinata d’Hondt & Occhipinti Ambrogi, 1985 for the Slovenian coastal sea. The colonies of this bryozoan were found attached to the mussel shells in the sight of Sečovlje, Strunjan and Debeli rtič mussel cultures from April to October 2018 and in Valdoltra harbour in November 2018. After the introduction into the Lagoon of Venice in the 1980s and its rapid spread throughout the lagoon in the following years, the species was regarded as an invasive taxon for that area and it is highly expected to colonize the whole Northern Adriatic region. The status of T. inopinata and its ecological impact has yet to be determined for the Slovenian coastal sea. Keywords: alien species, Gulf of Trieste, Adriatic Sea, mussel aquaculture Published in DiRROS: 07.08.2024; Views: 110; Downloads: 91
Full text (1,10 MB) This document has many files! More... |
53. Occurrence of ribbon fish (Trachipterus trachypterus) In Slovenian waters (Northern Adriatic Sea)Lovrenc Lipej, Domen Trkov, Borut Mavrič, 2018, other scientific articles Abstract: On 6th May 2018 a juvenile specimen of ribbon fish (Trachipterus trachypterus) was collected in shallow waters in Izola (Slovenia, northern Adriatic Sea). It measured 403 mm in total length and weighed 37.1 g. In stomach, fragments of seagrasses, pollen cones of pine, petals of terrestrial plant, fragments of terrestrial grass and beetles were found among food remains. The possible causes of this finding in Slovenian waters could be attributed to the ingression of southern Adriatic waters in its northern part. The specimen studied in this paper is the fifth record of this species in the Slovenian part of the Adriatic Sea. The cooperation between ichthyologists and fishermen proved to be crucial for the detection of the ribbon fish and other rare and less-known fish species, as well. Keywords: ribbon fish, occurrence (biology), diet, Adriatic Sea Published in DiRROS: 07.08.2024; Views: 116; Downloads: 94
Full text (1,26 MB) This document has many files! More... |
54. On the rare and less known shamefaced crab Calappa granulata (Brachyura, Calappidae) in the Northern Adriatic SeaNicola Bettoso, Marin Kirinčić, Borut Mavrič, Lovrenc Lipej, 2018, other scientific articles Abstract: On 1st August 2016 and 23th July 2017 two specimens of the shamefaced crab Calappa granulata (Linnaeus, 1758) were caught in the northernmost area of the Adriatic Sea and represent the second and third offi cial record, respectively. More recently the records of this commercial species start to be no more unusual in this northern region. It is too early to express any reliable comment regarding whether or not this species established a breeding population in this area, however we could consider its northward extension as another consequence of global warming. Keywords: shamefaced crab, northern Adriatic, global warming Published in DiRROS: 07.08.2024; Views: 116; Downloads: 89
Full text (1,18 MB) This document has many files! More... |
55. CXCR4 antagonists as stem cell mobilizers and therapy sensitizers for acute myeloid leukemia and glioblastoma?Vashendriya V. V. Hira, Cornelis J. F. van Noorden, Remco J. Molenaar, 2020, other scientific articles Abstract: Glioblastoma is the most aggressive and malignant primary brain tumor in adults and has a poor patient survival of only 20 months after diagnosis. This poor patient survival is at least partly caused by glioblastoma stem cells (GSCs), which are slowly-dividing and therefore therapy-resistant. GSCs are localized in protective hypoxic peri-arteriolar niches where these aforementioned stemness properties are maintained. We previously showed that hypoxic peri-arteriolar GSC niches in human glioblastoma are functionally similar to hypoxic peri-arteriolar hematopoietic stem cell (HSC) niches in human bone marrow. GSCs and HSCs express the receptor C-X-C receptor type 4 (CXCR4), which binds to the chemoattractant stromal-derived factor-1α (SDF-1α), which is highly expressed in GSC niches in glioblastoma and HSC niches in bone marrow. This receptor–ligand interaction retains the GSCs/HSCs in their niches and thereby maintains their slowly-dividing state. In acute myeloid leukemia (AML), leukemic cells use the SDF-1α–CXCR4 interaction to migrate to HSC niches and become slowly-dividing and therapy-resistant leukemic stem cells (LSCs). In this communication, we aim to elucidate how disruption of the SDF-1α–CXCR4 interaction using the FDA-approved CXCR4 inhibitor plerixafor (AMD3100) may be used to force slowly-dividing cancer stem cells out of their niches in glioblastoma and AML. Ultimately, this strategy aims to induce GSC and LSC differentiation and their sensitization to therapy.
Keywords: glioblastoma, glioblastoma stem cells, niches, acute myeloid leukemia, hematopoietic stem cells, bone marrow, C-X-C receptor type 4, stromal-derived factor-1 ▫$[alpha]$▫, plerixafor Published in DiRROS: 06.08.2024; Views: 148; Downloads: 188
Full text (1,51 MB) This document has many files! More... |
56. The role of natural science collections in the biomonitoring of environmental contaminants in apex predators in support of the EU’s zero pollution ambitionPaola Movalli, Jan Koschorreck, Gabriele Treu, Jaroslav Slobodnik, Nikiforos Alygizakis, Andreas Androulakakis, Alexander Badry, Emanuel Baltag, Fausto Barbagli, Kevin Bauer, Koos Biesmeijer, Al Vrezec, 2021, other scientific articles Abstract: The chemical industry is the leading sector in the EU in terms of added value. However, contaminants pose a major threat and significant costs to the environment and human health. While EU legislation and international conventions aim to reduce this threat, regulators struggle to assess and manage chemical risks, given the vast number of substances involved and the lack of data on exposure and hazards. The European Green Deal sets a ‘zero pollution ambition for a toxic free environment’ by 2050 and the EU Chemicals Strategy calls for increased monitoring of chemicals in the environment. Monitoring of contaminants in biota can, inter alia: provide regulators with early warning of bioaccumulation problems with chemicals of emerging concern; trigger risk assessment of persistent, bioaccumulative and toxic substances; enable risk assessment of chemical mixtures in biota; enable risk assessment of mixtures; and enable assessment of the effectiveness of risk management measures and of chemicals regulations overall. A number of these purposes are to be addressed under the recently launched European Partnership for Risk Assessment of Chemicals (PARC). Apex predators are of particular value to biomonitoring. Securing sufficient data at European scale implies large-scale, long-term monitoring and a steady supply of large numbers of fresh apex predator tissue samples from across Europe. Natural science collections are very well-placed to supply these. Pan-European monitoring requires effective coordination among field organisations, collections and analytical laboratories for the flow of required specimens, processing and storage of specimens and tissue samples, contaminant analyses delivering pan-European data sets, and provision of specimen and population contextual data. Collections are well-placed to coordinate this. The COST Action European Raptor Biomonitoring Facility provides a well-developed model showing how this can work, integrating a European Raptor Biomonitoring Scheme, Specimen Bank and Sampling Programme. Simultaneously, the EU-funded LIFE APEX has demonstrated a range of regulatory applications using cutting-edge analytical techniques. PARC plans to make best use of such sampling and biomonitoring programmes. Collections are poised to play a critical role in supporting PARC objectives and thereby contribute to delivery of the EU’s zero-pollution ambition. Keywords: zero pollution, biomonitoring, chemicals of emerging concern, Apex predator, raptor, marine mammal, otter Published in DiRROS: 06.08.2024; Views: 149; Downloads: 105
Full text (858,56 KB) This document has many files! More... |
57. Why do only males of Mawia benovici (Pelagiidae: Semaeostomeae: Scyphozoa) seem to onhabit the Northern Adriatic seaValentina Tirelli, Tjaša Kogovšek, Manja Rogelja, Paolo Paliaga, Massimo Avian, Alenka Malej, 2021, other scientific articles Abstract: This manuscript presents four new observations of the jellyfish Mawia benovici in the Adriatic Sea. This new species was recently identified as Pelagia benovici by Piraino et al. (2014) and then placed in the new genus Mawia by Avian et al. 2016. This species is rare and is almost exclusively observed in the Adriatic Sea. Interestingly, the majority of observations refer to males only. Few studies have addressed the issue of sex determination in Syphozoa in particular, as sex identity can only be determined at the medusa stage. Unfortunately, the rarity of M. benovici and the lack of female specimens have so far prevented indispensable laboratory studies to clarify its life cycle. Still, we tried to propose an explanation for our field observations.
Keywords: jellyfish, sex ratio, Mediterranean Sea Published in DiRROS: 06.08.2024; Views: 139; Downloads: 110
Full text (763,28 KB) This document has many files! More... |
58. A new tool for faster construction of marine biotechnology collaborative networksAna Rotter, Susana P. Gaudêncio, Katja Klun, Jan-Niklas Macher, Olivier Thomas, Irem Deniz, Christine Edwards, Ernesta Grigalionyte-Bembič, Z. Ljubešić, Johan Robbens, Giovanna Cristina Varese, Marlen I. Vasquez, 2021, other scientific articles Abstract: The increasing and rapid development in technologies, infrastructures, computational power, data availability and information flow has enabled rapid scientific advances. These entail transdisciplinary collaborations that maximize sharing of data and knowledge and, consequently, results, and possible technology transfer. However, in emerging scientific fields it is sometimes difficult to provide all necessary expertise within existing collaborative circles. This is especially true for marine biotechnology that directly addresses global societal challenges. This article describes the creation of a platform dedicated to facilitating the formation of short or mid-term collaborative networks in marine biotechnology. This online platform (https://www.ocean4biotech.eu/map/) enables experts (researchers and members of the marine biotechnology community in general) to have the possibility to showcase their expertise with the aim of being integrated into new collaborations/consortia on the one hand, or to use it as a search tool to complement the expertise in planned/running collaborations, on the other. The platform was created within the Ocean4Biotech (European transdisciplinary networking platform for marine biotechnology) Action, funded under the framework of the European Cooperation in Science and Technology (COST). To build the platform, an inquiry was developed to identify experts in marine biotechnology and its adjunct fields, to define their expertise, to highlight their infrastructures and facilities and to pinpoint the main bottlenecks in this field. The inquiry was open to all experts in the broad field of marine biotechnology, including non-members of the consortium. The inquiry (https://ee.kobotoolbox.org/single/UKVsBNtD) remains open for insertion of additional expertise and the resulting interactive map can be used as a display and search tool for establishing new collaborations.
Published in DiRROS: 06.08.2024; Views: 141; Downloads: 90
Full text (761,21 KB) This document has many files! More... |
59. A schematic sampling protocol for contaminant monitoring in raptorsSilvia Espín, Jovan Andevski, Guy Duke, Igor Eulaers, Pilar Gómez-Ramírez, Gunnar Thor Hallgrimsson, Al Vrezec, 2021, other scientific articles Abstract: Birds of prey, owls and falcons are widely used as sentinel species in raptor biomonitoring programmes. A major current challenge is to facilitate large-scale biomonitoring by coordinating contaminant monitoring activities and by building capacity across countries. This requires sharing, dissemination and adoption of best practices addressed by the Networking Programme Research and Monitoring for and with Raptors in Europe (EURAPMON) and now being advanced by the ongoing international COST Action European Raptor Biomonitoring Facility. The present perspective introduces a schematic sampling protocol for contaminant monitoring in raptors. We provide guidance on sample collection with a view to increasing sampling capacity across countries, ensuring appropriate quality of samples and facilitating harmonization of procedures to maximize the reliability, comparability and interoperability of data. The here presented protocol can be used by professionals and volunteers as a standard guide to ensure harmonised sampling methods for contaminant monitoring in raptors. Keywords: best practices, birds of prey, falcons, large-scale biomonitoring, owls, Pan-European network Published in DiRROS: 06.08.2024; Views: 136; Downloads: 73
Full text (744,64 KB) This document has many files! More... |
60. Editorial : The role of immune cells in the progression of autoimmune diseases affecting the CNSCzeslawa Kowal, Jelka Pohar, Flora Zavala, 2022, other scientific articles Abstract: Insights into the dynamics of immune responses in immune-privileged tissues such as the central nervous system (CNS) are critical to understanding the etiology of autoimmune diseases. Essential in this field is understanding the ways immune cells access and traffic across different types of the blood-brain barrier (BBB), and how the therapeutics alter these processes (see excellent review by Mapunda et al.). The current Research Topic brought into attention a diverse panel of original research papers and two reviews on the immune cells involved in CNS pathophysiology, including dendritic cells (DC), mucosal-associated invariant T (MAIT) cells, neutrophils, and pathogenic Th17 cells, as well as a different aspects of that pathophysiology, including molecular signaling pathways (PP2Cδ) and the role of signaling complexes, known as supramolecular organizing centers (SMOCs), therapeutic interventions (STAT3-specific nanobody, treatment of rheumatoid meningitis with intravenous immunoglobulin - IVIg), possible new forms of autoantigens (neutrophil extracellular traps (NETs) in neuropsychiatric systemic lupus erythematosus - NPSLE), and assessment of correlation between inflammatory markers and severity of autoimmune encephalitis (AE). Keywords: CNS pathophysiology, dendritic cells, mucosal-associated invariant T cells, STAT3, Th17 cells, PP2Cδ, supramolecular organizing centers (SMOCs), neutrophil extracellular traps, cytology Published in DiRROS: 06.08.2024; Views: 123; Downloads: 58
Full text (296,08 KB) This document has many files! More... |