1. Beyond compliance : developing and applying a situational questionnaire on research ethics in European public research organisationsŠpela Stres, 2025, original scientific article Abstract: This paper explores the development and use of a situational questionnaire designed to understand how ethical principles are comprehended, interpreted, and acted upon within European public research organisations. Moving beyond compliance-focused and regulatory views of research ethics, the questionnaire captures both personal and organisational perspectives on ethically sensitive situations, including principles such as reliability, honesty, respect, and accountability. Building on previous methodological work, the tool was utilised within the Joint Research Centre’s TTO Circle [1, 2] network to investigate how researchers and organisations perceive the need for ethical assessment across various scenarios. The findings highlight significant gaps between individual attitudes and institutional practices and reveal a tendency to prioritise well-established or formally regulated ethical areas over everyday research situations. The study demonstrates the usefulness of situational analysis in identifying tensions between autonomy and governance and underscores opportunities to strengthen ethics frameworks in research organisations through clearer, more transparent, and more context-aware approaches. Keywords: public research organizations Published in DiRROS: 14.01.2026; Views: 57; Downloads: 22
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2. Reduced ATP turnover during hibernation in relaxed skeletal muscleCosimo De Napoli, Luisa Schmidt, Mauro Montesel, Laura Cussonneau, Samuele Sanniti, Lorenzo Marcucci, Elena Germinario, Jonas Kindberg, Alina L. Evans, Marco Vincenzo Narici, 2025, original scientific article Abstract: Hibernating brown bears, due to a drastic reduction in metabolic rate, show only moderate muscle wasting. Here, we evaluate if ATPase activity of resting skeletal muscle myosin can contribute to this energy sparing. By analyzing single muscle fibers taken from the samebears,eitherduring hibernationorin summer,wefindthatfibersfromhibernatingbearshaveamilddeclineinforce production and a significant reduction in ATPase activity. Single fiber proteomics, western blotting, and immunohistochemical analyses reveal major remodeling of the mitochondrial proteome during hibernation. Furthermore, using bioinformatical approaches and western blotting we find that phosphorylated myosin light chain, a known stimulator of basal myosin ATPase activity, is decreased in hibernating and disused muscles. These results suggestthatskeletalmusclelimitsenergylossbyreducingmyosinATPaseactivity, indicating a possible role for myosin ATPase activity modulation in multiple muscle wasting conditions. Keywords: translational research, animal physiology, metabolism Published in DiRROS: 14.01.2026; Views: 53; Downloads: 27
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3. Supporting trans-national access to key nuclear research infrastructures – OFFERR and JRC OASIS : two complementary projects – one goalCharles Toulemonde, Alice Seibert, Eric Colineau, Leon Cizelj, Raffaella Canu, 2025, original scientific article Abstract: The OFFER and OASIS projects both provide transnational access to key nuclear research infrastructures. Since September 2022, the OFFERR project, funded by Horizon Europe/Euratom, supports the SNETP Association by providing R&D experts access to key nuclear research infrastructures across Europe. It addresses financial and logistical barriers that hinder nuclear research by offering a platform for financial support and access to more than 230 experimental facilities. Researchers can submit applications through the OFFERR Call Platform, ensuring eligible projects receive necessary funding and access. This initiative aims to accelerate innovation in nuclear energy by bridging the gap between research ideas and advanced facilities, adhering to EU regulations and fostering international collaboration. The OASIS project is funded by an Administrative Arrangement between the Directorate General for Research and Innovation (DG RTD) and JRC since February 2020 and aims at enhancing open access to JRC's nuclear facilities (11 out of 16 are opened) and the associated technical support. So in the OASIS project, JRC makes available its nuclear research infrastructures to external users free of charge while DG RTD provides their financial support to eligible users to cover their travel and subsistence costs. This allows an optimal use of JRC's unique facilities and nuclear materials not available to European scientists at their home institutions and results in scientific excellence in research that could otherwise not be performed. With a large participation of students and young scientists, OASIS also contributes to the training of the next generation of European scientists in various nuclear fields. Whereas the two projects have one goal, they follow complementary approaches. Keywords: nuclear research infracstructure Published in DiRROS: 13.01.2026; Views: 62; Downloads: 37
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4. Global health at crossroads : uniting together to overcome challenges, restore trust and advance priorities for a sustainable futureMassimo Sartelli, Elias Mossialos, Federico Coccolini, Ib Jammer, Francesco M. Labricciosa, Philip S. Barie, Walter L. Biffl, Ziad A. Memish, Markus Maeurer, 2025, other scientific articles Abstract: The world is currently facing an unprecedented convergence of crises that threaten the core pillars of public health, scientific integrity, and social stability. These challenges are profoundly interconnected and have the potential to exacerbate global inequalities, jeopardize health security, and undermine the progress achieved through decades of international collaboration. Our viewpoint declaration, developed by 366 healthcare workers and scientists from 119 countries across six continents, highlights the urgent need for global solidarity and collective action to address these interconnected global health challenges. As healthcare workers and scientists, we must prioritize the protection of scientific integrity, combat political interference, and restore public trust in the scientific process. This will require a commitment to transparency, ethical responsibility, and evidence-based decision-making that can stand strong in the face of political and social adversity. The COVID-19 pandemic has underscored the critical importance of resilient healthcare systems, emphasizing that preparedness, capacity building and coherent leadership and coordination are essential for future global health crises. In addition, our call for a One Health approach, acknowledging the intricate relationship between human, animal, and environmental health, has never been more pressing, especially as zoonotic diseases and antimicrobial resistance spread across borders. As we confront ongoing wars, environmental destruction, and global persistent health inequalities, it is only through unity, solidarity, collaboration, and innovation that we hope to build a healthier, more equitable world. Together, we must ensure that science and medicine remain a force for good, capable of addressing both the immediate and long-term needs and challenges facing our shared future. Keywords: antimicrobial resistance, artificial intelligence, climate change, global health, healthcare systems, infectious diseases, misinformation, one health, public health, scientific research Published in DiRROS: 08.01.2026; Views: 87; Downloads: 40
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5. “Challenging but worth it!” : the purpose of participatory research in urban health, an evaluation and derived frameworkMaria Alejandra Rubio, Rok Novak, Laura Hidalgo, Jill Litt, Don Slater, David Kocman, 2026, original scientific article Abstract: Participatory approaches are becoming paramount to harness the relationship between researchers, government, industry, and civil society to inform programs and policies. However, variability in implementation and limited standardized reporting hinder the systematic evaluation of their effectiveness. This study characterizes participatory methodologies in urban health research and proposes a framework for evaluating and reporting such approaches. Using an explanatory sequential design, this study evaluated 20 participatory pilot studies from the Urban Health Cluster (Horizon 2020 European Commission Programme), combining survey data and semi-structured interviews with project leads. The analysis identified four primary purposes for participatory methods: to assess health-environment correlations; raise awareness; co-create interventions; and assess health-related effects. Case studies exemplify each of these purposes. Findings informed a “purpose framework” nested within a theory-of-change model, which clarifies the rationale behind participatory approaches and maps their processes and intended impacts. The framework includes indicators for purpose, stakeholder involvement, participation mechanisms, facilitators, challenges, expected outcomes, and evaluation strategies, reported across all 20 projects. Public authorities (90 %) and civil society (85 %) are the most frequently engaged stakeholders, typically involved during project identification and deployment. Engagement was facilitated by shared motivation to address local needs, while long-term commitment posed challenges. Our results highlight the limited use of theory-of-change models in current practice and the value of structured frameworks for enhancing the reproducibility and transformative impact of participatory urban health research. The proposed framework can help align participatory methods with a theory of change and foster more effective urban health transformations. Keywords: participatory research, public engagement, standardized reporting, urban health Published in DiRROS: 03.12.2025; Views: 354; Downloads: 83
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6. Global Impacts Dataset of Invasive Alien Species (GIDIAS)Sven Bacher, Ellen Ryan-Colton, Mario Coiro, Phillip Cassey, Bella S. Galil, Martin A. Nuñez, Michael Ansong, Katharina Dehnen-Schmutz, Georgi Fayvush, Romina D. Fernandez, Maarten De Groot, 2025, complete scientific database of research data Abstract: We present the Global Impacts Dataset of Invasive Alien Species (GIDIAS), a global dataset of 22865 records including impacts of invasive alien species on nature, nature’s contributions to people, and good quality of life. Records include positive and negative impacts, neutral impacts (studies were carried out, but no impacts were documented), non-directional impacts (i.e., change without detriments or benefits for native species or people), and finally, some records of alien species where no studies were found that assessed their impacts (indicating data gaps). Records cover 3353 invasive alien species from all major taxa (plants, vertebrates, invertebrates, microorganisms) and all continents and realms (terrestrial, freshwater, marine). The data were compiled to serve as robust evidence for chapter 4 “Impacts of invasive alien species on nature, nature's contributions to people, and good quality of life” of the global assessment report on invasive alien species by the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES; available on Zenodo at https://doi.org/10.5281/zenodo.7430731). The dataset is provided in a machine-readable CSV file (file name GIDIAS_20250417_machine_read.csv), with special language characters retained where used (UTF-8 format). The dataset is also provided in Excel format (file name GIDIAS_20250417_Excel.xlsx). Metadata is provided in Excel format, including descriptors for each variable (file name GIDIAS_metadata_20250417.xlsx). Additional explanations for GIDIAS is stored in Microsoft Word format (docx) and contains (1) a short description of the principles of Environmental and Socio-Economic Impact Classification for Alien Taxa (EICAT, SEICAT), (2) a description of the variables included in the Global Impacts Dataset of Invasive Alien Species GIDIAS, and (3) a compilation of the search strategies and datasets included in the Global Impact Dataset of Invasive Alien Species (GIDIAS). Keywords: invasive alien species, research data Published in DiRROS: 01.12.2025; Views: 274; Downloads: 115
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7. Project management digitalisation of the clinical research at the University Medical Centre : good practice of using REDCap as a digitalisation toolZdenko Garaševič, Franc Strle, Martina Jaklič, 2025, original scientific article Abstract: Objective: The digital tool REDCap (Research Electronic Data Capture) was implemented at the University Medical Centre Ljubljana (UMCL) with the goal of digitalising and streamlining research processes. This study aimed to assess the efficiency and transparency of clinical research following the implementation of REDCap. Methods: The implementation of REDCap for funded research began in 2021. It comprised four key steps: (I) the initial creation of Central Research Registry, followed by additional functionalities including (II) the establishment of the Central Database for ’Pre-Contract Activities’ for clinical trials; (III) the integration of Reporting on Research Progress directly into the Central Research Registry; and (IV) the development of a semi-automated Workflow for internal agreements. Results: Between 2021 and 2023, UMCL established a Central Research Registry using REDCap, transitioning from paper-based to digital data collection for over 2,500 research projects. These projects included clinical trials, national and international studies, as well as academic research. In addition to serving as a registry, the central system provided comprehensive data management, streamlined communication, and enhanced collaboration among stakeholders in clinical trial research at UMCL. The implementation of REDCap significantly reduced administrative burden and shortened the time required to finalise clinical trial agreements from 202 to 147 days. It also improved coordination, transparency, and real-time monitoring of research activities, facilitating more efficient research execution. Additionally, the digitalisation of internal agreements processes between researchers and stakeholders within UMCL improved coordination and expedited research execution timelines. Furthermore, REDCap enabled real-time monitoring of research progress, further contributing to the efficiency and transparency of research activities. Conclusion: The digitalisation of research processes using REDCap improved the organisation and execution of research, leading to greater efficiency and transparency, reduced administrative workload, and enhanced collaboration. This approach contributed to higher-quality research outcomes and ultimately benefited patient care. Keywords: digitalisation, REDCap, clinical research, efficiency, transparency, research registry, data management Published in DiRROS: 24.11.2025; Views: 319; Downloads: 104
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8. The process and procedures for the preparation of integrated maritime spatial planning : the case of SloveniaBarbara Goličnik Marušić, Andrej Gulič, 2025, original scientific article Abstract: This article explores the establishment of a maritime spatial planning (MSP) framework in Slovenia. Following revised spatial planning legislation and the Directive 2014/89/EU, Slovenia initiated the development of processes and procedures for integrated MSP. Drawing on a dedicated research project, the article presents a proposed methodology grounded in the ecosystem approach, forming a foundation for integrated land–sea interaction planning. The framework outlines a four‐phase process: (1) preliminary MSPlan preparation, (2) MSPlan preparation, (3) MSPlan monitoring and evaluation of implementation, and (4) ongoing MSPlan monitoring and updating. Each phase consists of independent or sequential steps, which are also linked procedurally between the phases. A central feature linking the preliminary and main preparation phases is stakeholder involvement. While the MSPlan preparation phase ensures broad stakeholder participation, the preliminary phase engages those representing strategic development or conservation interests. Experts and other stakeholder groups may also be involved directly in the planning process. The article concludes by evaluating the adopted Slovenian MSPlan, highlighting deviations from the proposed process and assessing the extent of its implementation in relation to the original plan. It also emphasises the importance of developing the MSP process and its procedures in parallel to ensure strong alignment and facilitate a smoother preparation of the final MSPlan. Keywords: coastal governance, research, maritime spatial planning, North Adriatic Sea Published in DiRROS: 20.11.2025; Views: 184; Downloads: 73
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10. Mapping temperature, humidity, air quality, and noise-related comfort conditions to identify urban planning issues : a case of study of Ljubljana, SloveniaŽiva Ravnikar, Alfonso Bahillo, Barbara Goličnik Marušić, 2025, original scientific article Keywords: public space, research, urban planning Published in DiRROS: 20.11.2025; Views: 225; Downloads: 54
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