121. Vaskularizacija in vaskularni učinki kot prognostični dejavniki za zdravljenje tumorjev z lokalnimi ablacijskimi tehnikamiTadej Tomanič, Črt Keber, Jošt Stergar, Boštjan Markelc, Tim Božič, Simona Kranjc Brezar, Gregor Serša, Matija Milanič, 2023, objavljeni povzetek znanstvenega prispevka na konferenci Ključne besede: medicinska fizika, medicinsko slikanje, hiperspektralno slikanje, tumorji, zdravljenje
Objavljeno v DiRROS: 16.06.2023; Ogledov: 355; Prenosov: 89
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122. Forest managers’ perspectives on environmental changes in the biosphere reserve Mura-Drava-DanubeMarcus Sallmannshofer, Rok Damjanić, Harald Vacik, Marjana Westergren, Tjaša Baloh, Gregor Božič, Mladen Ivanković, Gyula Kovács, Miran Lanšćak, Katharina Lapin, Laszlo Nagy, Silvija Krajter Ostoić, Saša Orlović, Srđan Stojnić, Peter Železnik, Milica Zlatković, Silvio Schueler, 2023, izvirni znanstveni članek Povzetek: Riparian forests are particularly vulnerable to environmental change and anthropogenic influences because they are highly dynamic ecosystems, thus proper adaptation measures are crucial. The implementation of these measures, however, strongly depends on the actors’ perceptions of the specific problems occurring in such forests. For understanding the constraints of specific interest groups toward different adaptation activities, information in this field is essential. By conducting a questionnaire survey we explore how different types of forest managers, i.e., forestry professionals, forest owners, and conservation managers, perceive the effects of environmental change on forest management in the recently established Transboundary Biosphere Reserve Mura-Drava-Danube. We show that these forest managers are highly aware of ongoing environmental changes and appraise deteriorating forest conditions, especially after observing changes themselves. Abiotic damage is expected to increase the most, followed by biotic damage, the spread of non-native species, and tree dieback. Nearly 80% of the survey respondents expect further changes and almost all of them intend to adapt their management of forests to mitigate or prepare for these changes. Nevertheless, we show differences in sensitivity to change and willingness to initiate adaptation actions by assessing adaptation thresholds: conservation managers appear generally more tolerant to changes, which results in higher thresholds to initiate management adaptation than forestry professionals
Ključne besede: biosphere reserve Mura-Drava-Danube, forest management, sensitivity to environmental change, stakeholder perception, adaptation thresholds, riparian forest tree species
Objavljeno v DiRROS: 31.05.2023; Ogledov: 343; Prenosov: 269
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123. |
124. Obravnava bolnic s sumom na raka telesa materniceGregor Vivod, 2023, objavljeni znanstveni prispevek na konferenci Povzetek: Z naraščajočo incidenco raka materničnega telesa v razvitem svetu je v prihodnjih letih
ocenjeno, da bo v Sloveniji za rakom materničnega telesa zbolelo več kot 400 bolnic letno. Z
obravnavo bolnic s sumom ali že znanim rakom telesa maternice se sreča vsak ginekolog.
Začetna obravnava bolnic vključuje anamnezo (družinska, osebna, ginekološka, sedanja),
splošni klinični pregled ter ginekološki klinični pregled z vaginalnim ultrazvokom. V nadaljnji
obravnavi sledi potrditev diagnoze (histeroskopija, abrazija ali aspiracijska biopsija) ter glede
na klinično presojo ustrezna slikovna diagnostika (CT, MR, PET-CT). Stremeti moramo k
optimalni in čimprejšnji diagnostični obravnavi na primarni in sekundarni ravni ter na
učinkovitem zdravljenju (operativni poseg, obsevanje, sistemsko zdravljenje) na terciarni ravni.
Po končanem zdravljenju morajo biti vse bolnice ustrezno sledene.
Ključne besede: rak maternice, ginekološki raki, ginekološka onkologija
Objavljeno v DiRROS: 30.05.2023; Ogledov: 237; Prenosov: 90
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125. Application of electrochemical methods for studying steel corrosion in alkali-activated materialsShishir Mundra, Gabriel Samson, Giulia Masi, Rebecca Achenbach, David M. Bastidas, Susana Bernal, Maria Chiara Bignozzi, Maria Criado, Martin Cyr, Nina Gartner, Stefanie von Greve‐Dierfeld, Andraž Legat, Nikoonasab Ali, John L. Provis, Michael Raupach, Gregor J. G. Gluth, 2023, izvirni znanstveni članek Povzetek: Alkali‐activated materials (AAMs) are binders that can complement and partially substitute the current use of conventional cement. However, the present knowledge about how AAMs protect steel reinforcement in concrete elements is incomplete, and uncertainties exist regarding the application of electrochemical methods to investigate this issue. The present review by EFC WP11‐Task Force ‘Corrosion of steel in alkali‐activated materials’ demonstrates that important differences exist between AAMs and Portland cement, and between different classes of AAMs, which are mainly caused by differing pore solution compositions, and which affect the outcomes of electrochemical measurements. The high sulfide concentrations in blast furnace slag‐based AAMs lead to distinct anodic polarisation curves, unusually low open circuit potentials, and low polarisation resistances, which might be incorrectly interpreted as indicating active corrosion of steel reinforcement. No systematic study of the influence of the steel–concrete interface on the susceptibility of steel to corrosion in AAMs is available. Less common electrochemical methods present an opportunity for future progress in the field.
Ključne besede: alkali-aktivated materials, alkali‐activated materials, anodic/cathodic polarisation, concrete, linear polarisation resistance, open circuit potential, reinforcement corrosion, resistivity
Objavljeno v DiRROS: 29.05.2023; Ogledov: 282; Prenosov: 122
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126. Rak telesa maternice : 7. Šola o ginekološkem raku2023, ni določena Povzetek: Pred vami je zbornik, kjer so zbrani prispevki predavanj s področij, ki obravnavajo etiologijo in epidemiologijo raka materničnega telesa, predstavljene so najnovejše smernice obravnave bolnic z rakom materničnega telesa, novosti na področju patološke in molekularne diagnostike, na področju slikovne diagnostike ter dileme na področju operativnega zdravljenja. V zadnjem delu zbornika je predstavljeno sistemsko zdravljenje raka materničnega telesa ter zdravljenje z obsevanjem.
Objavljeno v DiRROS: 24.05.2023; Ogledov: 342; Prenosov: 115
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128. Elektrokemoterapija pri zdravljenju raka in genska imunoterapija pri bazalno celičnem karcinomu : klinična študija faze IGregor Serša, Maja Čemažar, 2023, objavljeni znanstveni prispevek na konferenci Povzetek: Elektrokemoterapija je lokalna ablativna terapija, ki temelji na uporabi elektroporacije, kot dostavnega sistema za citostatika bleomicin ali cisplatin. Njena uporaba je predvsem za zdravljenje kožnih tumorjev, kot so kožne metastaze melanoma ali bazalno celični karcinomi. Elektrokemoterapija je v smernicah mnogih evropskih držav. Učinkovitost elektrokemoterapije je v povprečju za vse vrste kožnih tumorjev, 86% objektivnih odgovorov (OR) in 71% popolnih odgovorov (CR) po enkratni terapiji. Za zdravljenje so objavljeni standardizirani postopki, na voljo je več certificiranih generatorjev električnih pulzov in različni tipi elektrod. Obstajajo pa razlike v stopnji odgovorov med različnimi tumorji. Bazalno celični so najbolj občutljivi, melanomski tumorji pa manj. Klinični napovedni dejavniki so zato vrsta tumorjev, ter velikost tumorjev in predhodna zdravljenja. Nedavne študije so dokazale sinergizem njenega delovanja z zaviralci imunskih kontrolnih točk pri bolnikih z melanomom. Na bazalno celičnem karcinomu se izvaja tudi faza I kliničnega preskušanja, katerega namen je preučiti varnost in sprejemljivost zdravila za gensko terapijo, plazmida phIL12.
Ključne besede: rak kože, melanom, elektrokemoterapija
Objavljeno v DiRROS: 18.05.2023; Ogledov: 221; Prenosov: 91
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129. Environmental hazard of polypropylene microplastics from disposable medical masks : acute toxicity towards Daphnia magna and current knowledge on other polypropylene microplasticsAnita Jemec Kokalj, Andraž Dolar, Damjana Drobne, Marjan Marinšek, Matej Dolenec, Luka Škrlep, Gregor Strmljan, Branka Mušič, Andrijana Sever Škapin, 2022, izvirni znanstveni članek Povzetek: The COVID-19 pandemic has increased the use of disposable plastics, including medical masks, which have become a necessity in our daily lives. As these are often improperly disposed of, they represent an important potential source of microplastics in the environment. We prepared microplastics from polypropylene medical masks and characterised their size, shape, organic chemical leaching, and acute toxicity to the planktonic crustacean Daphnia magna. The three layers of the masks were separately milled and characterised. Each of the inner frontal, middle filtering, and outer layers yielded different types of microplastics: fibres were obtained from the inner and outer layer, but irregular fragments from the middle layer. The shape of the obtained microplastics differed from the initial fibrous structure of the intact medical mask layers, which indicates that the material is deformed during cryo-milling. The chemical compositions of plastics-associated chemicals also varied between the different layers. Typically, the inner layer contained more chemicals related to antimicrobial function and flavouring. The other two layers also contained antioxidants and their degradation products, plasticisers, cross-linking agents, antistatic agents, lubricants, and non-ionic surfactants. An acute study with D. magna showed that these microplastics do not cause immobility but do physically interact with the daphnids. Further long-term studies with these microplastics are needed using a suite of test organisms. Indeed, studies with other polypropylene microplastics have shown numerous adverse effects on other organisms at concentrations that have already been reported in the environment. Further efforts should be made to investigate the environmental hazards of polypropylene microplastics from medical masks and how to handle this new source of environmental burden.
Ključne besede: COVID-19 pandemic, plastics-associated chemicals, Daphnia magna, fibres, fragments, nanofibres, polypropylene microplastics, single-use plastic
Objavljeno v DiRROS: 05.05.2023; Ogledov: 335; Prenosov: 212
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130. Synthesis and characterization of plasmonic ▫$Au/TiO_2$▫ nanorod solids for heterogeneous photocatalysisŠpela Slapničar, Gregor Žerjav, Janez Zavašnik, Matjaž Finšgar, Albin Pintar, 2023, izvirni znanstveni članek Povzetek: Plasmonic Au (1 wt%) catalysts deposited on hydrothermally synthesized TiO2 nanorods (TNR) were investigated in this study. Based on the duration of mixing of the Au precursor/TNR suspension during the wet impregnation synthesis and parameters of the end calcination, Au/TiO2 catalysts with different sizes of Au nanoparticles (Au NPs) were obtained. The prepared solids were thoroughly characterized by several instrumental techniques to investigate property-activity relationships. Regardless of the size of Au particles on the catalyst surface, an absorption peak at 550 nm occurred in all UV-Vis diffuse reflectance spectra of the investigated Au/TiO2 catalysts, which is characteristic of the localized surface plasmon resonance effect exerted by metallic Au NPs. By measuring the formation of reactive oxygen species under visible-light illumination using various scavengers, the production of superoxide anion radicals (O2•single bond) and hydroxyl radicals were identified, however, the former were found to represent the main reactive oxygen species that govern the oxidation of aqueous bisphenol A (BPA) employed as a model organic pollutant. The activity of Au/TiO2 catalysts for the generation of O2•single bond radicals (and BPA oxidation) increases by increasing the Schottky barrier height, which is due to the slow reduction of water-dissolved O2 on the catalyst surface.
Ključne besede: heterogeneous photocatalysis, titanate nanorods, gold nanoparticles, wet impregnation, localized surface plasmon resonance effect
Objavljeno v DiRROS: 26.04.2023; Ogledov: 471; Prenosov: 215
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