1. Establishment of a virtual transborder tumor board for cancer patients in Central and Southeastern Europe : an initiative of the Central European Cooperative Oncology Group (CECOG)Christiane Thallinger, Peter Berzinec, Emina Bicakcic, Adelina Dan, Gabriella Fabian, Laurentia Nicoletta Gales, Cvetka Grašič-Kuhar, Urška Janžič, Marina Mencinger, Christoph Zielinski, 2022, original scientific article Abstract: o establish a transborder virtual tumor board (VTB) fostering state-of-the-art management of cancer patients by exchanging knowledge and expertise among oncologists in Central and Southeastern Europe (CEE). Methods: We established and implemented a VTB based on the WebEx platform. This allowed for password-protected and secure upload of patient cases to be presented and discussed among colleagues from various oncology centers scattered throughout CEE in order to arrive at a recommendation for further diagnoses and/or treatment. Results: A total of 73 cases from 16 oncology centers located in 11 CEE countries were uploaded by 22 physicians; 71 were discussed over the course of 17 virtual meetings between June 2018 and May 2019 and 12 different kinds of malignant diseases were discussed with lung cancer (46.6%), melanoma (19.2%) and bladder cancer (13.6%) being the most commonly presented tumor entities. Of the discussed patients, 93.3% had stage IV disease at the time of presentation, 62.6% received chemotherapy or targeted treatment and 67.1% were treated with immune checkpoint inhibitors (ICPIs). The most common causes for presentation and discussion of patient cases were related to the use of ICPIs (80%). Conclusion: When the need for expertise exceeds locally available resources, web-based VTBs provide a feasible way to discuss patient cases and arrive at conclusions regarding diagnoses and/or treatment across large geographic distances. Moreover, VTBs provide an innovative way for proper, state-of-the-art management of patients with malignant diseases in times of social distancing and the resulting need for restricted interaction during the current SARS-CoV‑2 (severe acute respiratory syndrome coronavirus type 2) pandemic.
Keywords: CECOG, Osrednja in jugovzhodna Evropa, nadzorni imunski zaviralci, maligne bolezni
Published in DiRROS: 31.03.2022; Views: 184; Downloads: 109
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5. Multidisciplinarna obravnava bolnikov z urogenitalnimi rakiBoštjan Šeruga, Barbara Šegedin, Janka Čarman, Manja Šešek, Borut Kragelj, Helena-Barbara Zobec Logar, Simona Borštnar, Marina Mencinger, Tomaž Milanez, Breda Škrbinc, 2014, published scientific conference contribution Keywords: rak prostate, rak mod, radioterapija, kirurgija, internistična onkologija, urogenitalni raki
Published in DiRROS: 17.09.2019; Views: 1746; Downloads: 535
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7. Razsejan rak dojkSimona Borštnar, Jožica Červek, Maja Ebert Moltara, Cvetka Grašič-Kuhar, Tanja Marinko, Erika Matos, Marina Mencinger, Tanja Roš-Opaškar, Boštjan Šeruga, Erik Škof, Andreja Cirila Škufca Smrdel, 2013, dictionary, encyclopaedia, lexicon, manual, atlas, map Abstract: Več kot tisoč dvesto žensk vsako leto zboli za rakom dojk. Ko se bolnica in njeni zdravniki po postavitvi diagnoze spopademo z boleznijo, skušamo narediti vse, da bolezen pozdravimo. Z operacijo odstranimo tumor ali celo dojko in eno ali več pazdušnih bezgavk, nato pa dojko ali področje odstranjene dojke velikokrat še dodatno obsevamo.
Keywords: hormonsko zdravljenje, stranski učinki, kemoterapija, radioterapija, metastaziranje, paliativna oskrba, klinične ratiskave
Published in DiRROS: 25.03.2019; Views: 2152; Downloads: 620
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8. Stranski učinki ob zdravljenju rakavih bolezni z zaviralci tirozinskih kinazMarina Mencinger, 2018, professional article Abstract: Zaviralci tirozin-kinaz so multitarčna zdravila, ki prek zaviranja različnih celičnih procesov učinkujejo pri več vrstah rakavih boleznih. Čeprav so stranski učinki ob zaviralcih tirozinskih kinaz v splošnem prenosljivi, pa so lahko tudi resni in povzročajo nemalo preglavic bolnikom, ki prejemajo zdravila dolgotrajno. Pogosto je potrebno zmanjšanje odmerkov ali prehodna ukinitev, redkeje pa se odločimo za trajno prekinitev zdravljenja. Značilni so kožna toksičnost, kardiovaskularni zapleti, težave gastrointestinalnega trakta - predvsem diareja, nepravilno delovanje ščitnice in utrujenost ob zdravljenju rakave bolezni.
Keywords: tarčna zdravila, zaviralci tirozinskih kinaz, stranski učinki
Published in DiRROS: 26.10.2018; Views: 2374; Downloads: 607
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9. Rak dojke pri mladih ženskah in nosečnostMarina Mencinger, Jasna But Hadžić, 2014, review article Abstract: Rak dojke pri mladih bolnicah je redek pojav. Uspešno zdravljenje te bolezni omogoča večini mladih bolnic dolgo preživetje. Pomemben vidik kakovosti življenja je nedvomno ohranjanje plodnosti, posebno ob zavedanju, da je starost žensk ob prvem otroku vse višja. Mlade bolnice je zato treba že ob postavitvi diagnoze seznaniti z možnimi negativnimi vplivi zdravljenja na plodno sposobnost in jim ponuditi možnost svetovanja. Na ginekološko-onkološkem konziliju bolnicam ali paru med drugim predstavimo postopke za shranjevanje genetskega materiala pred pričetkom zdravljenja. V pričujočem prispevku predstavljamo in razpravljamo o novejših spoznanjih, ki povezujejo rak dojke ter nosečnost. Predstavljamo tudi zbrane podatke o nosečnostih pri zelo mladih bolnicah po zdravljenju raka dojke v Sloveniji.
Keywords: rak dojke, nosečnost, plodnost, mlade bolnice
Published in DiRROS: 31.08.2018; Views: 2561; Downloads: 648
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