1. Massively parallel measurement of protein–protein interactions by sequencing using MP3-seqAlexandr Baryshev, Benjamin Groves, Cirstyn Michel, David Baker, Ajasja Ljubetič, Georg Seelig, 2024, izvirni znanstveni članek Ključne besede: proteins, proteins interactions, sequencing, MP3-seq
Objavljeno v DiRROS: 30.10.2024; Ogledov: 211; Prenosov: 906
 Celotno besedilo (4,42 MB)
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2. Comparative simulative analysis and design of single-chain self-assembled protein cagesFei Xiao, Longfei Luo, Xin Liu, Ajasja Ljubetič, Nengzhi Jin, Roman Jerala, Guang Hu, 2024, izvirni znanstveni članek Povzetek: Coiled-coil protein origami (CCPO) is a modular strategy for the de novo design of polypeptide nanostructures. It represents a type of modular design based on pairwise-interacting coiled-coil (CC) units with a single-chain protein programmed to fold into a polyhedral cage. However, the mechanisms underlying the self-assembly of the protein tetrahedron are still not fully understood. In the present study, 18 CCPO cages with three different topologies were modeled in silico. Then, molecular dynamics simulations and CC parameters were calculated to characterize the dynamic properties of protein tetrahedral cages at both the local and global levels. Furthermore, a deformed CC unit was redesigned, and the stability of the new cage was significantly improved.
Ključne besede: chemical structure, conformation, genetics oligomers stability
Objavljeno v DiRROS: 03.10.2024; Ogledov: 228; Prenosov: 55
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3. Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivoAjasja Ljubetič, Fabio Lapenta, Helena Gradišar, Igor Drobnak, Jana Aupič, Žiga Strmšek, Duško Lainšček, Iva Hafner Bratkovič, Andreja Majerle, Nuša Krivec, Mojca Benčina, Tomaž Pisanski, Tanja Ćirković-Veličković, Adam Round, José María Carazo, Roberto Melero, Roman Jerala, 2017, izvirni znanstveni članek Objavljeno v DiRROS: 17.04.2018; Ogledov: 4589; Prenosov: 2932
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