1. The role of extracellular vesicles in phenotypic cancer transformationEva Ogorevc, Veronika Kralj-Iglič, Peter Veranič, 2013, pregledni znanstveni članek Povzetek: Background. Cancer has traditionally been considered as a disease resulting from gene mutations. New findings in biology are challenging gene-centered explanations of cancer progression and redirecting them to the non-genetic origins of tumorigenicity. It has become clear that intercellular communication plays a crucial role in cancer progression. Among the most intriguing ways of intercellular communication is that via extracellular vesicles (EVs). EVs are membrane structures released from various types of cells. After separation from the mother membrane, EVs become mobile and may travel from the extracellular space to blood and other body fluids. Conclusions. Recently it has been shown that tumour cells are particularly prone to vesiculation and that tumour-derived EVs can carry proteins, lipids and nucleic acids causative of cancer progression. The uptake of tumour-derived EVs by noncancerous cells can change their normal phenotype to cancerous. The suppression of vesiculation could slow down tumour growth and the spread of metastases. The purpose of this review is to highlight examples of EV-mediated cancer phenotypic transformation in the light of possible therapeutic applications.
Objavljeno v DiRROS: 03.04.2024; Ogledov: 55; Prenosov: 24
 Celotno besedilo (864,38 KB)
Gradivo ima več datotek! Več... |
2. Short term effect of plant hybridosomes on growth of phaeodactylum tricornutum cultureAnna Romolo, Matej Hočevar, Aleš Iglič, Tjaša Griessler Bulc, Veronika Kralj-Iglič, 2023, objavljeni znanstveni prispevek na konferenci Ključne besede: Phaeodactylum tricornutum, hybridosomes, liposomes, nanoalgosomes, extracellular vesicles, small cellular particles, microalgae
Objavljeno v DiRROS: 21.03.2024; Ogledov: 83; Prenosov: 42
Celotno besedilo (2,00 MB)
Gradivo ima več datotek! Več... |
3. |
4. |
5. |
6. Scanning electron microscope images of isolates of small cellular particles Phaeodactylum tricornutum grown in media supplemented with Guillard’s (F/2) marine : marine water enrichment solution, BG11 broth and Lennox LB brothApolonija Bedina Zavec, Darja Božič, Matej Hočevar, Aleš Iglič, Marko Jeran, Veronika Kralj-Iglič, Anna Romolo, 2024, objavljeni znanstveni prispevek na konferenci Objavljeno v DiRROS: 08.03.2024; Ogledov: 85; Prenosov: 43
Celotno besedilo (13,06 MB)
Gradivo ima več datotek! Več... |
7. |
8. |
9. Small cellular particles from European spruce needle homogenateMarko Jeran, Anna Romolo, Vesna Spasovski, Matej Hočevar, Urban Novak, Roman Štukelj, Vid Šuštar, Matic Kisovec, Apolonija Bedina Zavec, Ksenija Kogej, Aleš Iglič, Polonca Trebše, Veronika Kralj-Iglič, 2023, izvirni znanstveni članek Ključne besede: Picea abies, spruce needles, extracellular particles, extracellular vesicles, small cellular particles, interferometric light microscopy, exosomes, cell-to-cell communication, drug delivery
Objavljeno v DiRROS: 07.02.2024; Ogledov: 152; Prenosov: 99
Celotno besedilo (2,49 MB)
Gradivo ima več datotek! Več... |
10. Inflammatory, oxidative stress and small cellular particle response in HUVEC induced by debris from endoprosthesis processingZala Jan, Matej Hočevar, Veno Kononenko, Sara Michelini, Neža Repar, Maja Caf, Boštjan Kocjančič, Drago Dolinar, Slavko Kralj, Darko Makovec, Aleš Iglič, Damjana Drobne, Monika Jenko, Veronika Kralj-Iglič, 2023, izvirni znanstveni članek Ključne besede: endoprosthesis failure, corundum, cytokines, reactive oxygen species, lipid droplets
Objavljeno v DiRROS: 02.02.2024; Ogledov: 173; Prenosov: 65
Celotno besedilo (4,34 MB)
Gradivo ima več datotek! Več... |
