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22. Dispersoids in Al-Mg-Si alloy AA 6086 modified by Sc and YFranc Zupanič, Sandi Žist, Mihaela Albu, Ilse Letofsky-Papst, Jaka Burja, Maja Vončina, Tonica Bončina, 2023, izvirni znanstveni članek Ključne besede: aluminium alloy, heat treatment, microstructure, dispersoids, dilatometry, DSC, hardness
Objavljeno v DiRROS: 02.02.2024; Ogledov: 138; Prenosov: 74
 Celotno besedilo (11,03 MB)
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23. Effect of sucrose concentration on streptococcus mutans adhesion to dental material surfacesAnamarija Zore, Franc Rojko, Nives Matijaković Mlinarić, Jona Veber, Aleksander Učakar, Roman Štukelj, Andreja Pondelak, Andrijana Sever Škapin, Klemen Bohinc, 2024, izvirni znanstveni članek Povzetek: Enamel demineralization, known as dental caries, is instigated by the bacterium Streptococcus mutans, which generates acid during carbohydrate metabolism. Among carbohydrates, sucrose is the most cariogenic and capable of biofilm formation. This study aimed to explore and comprehend Streptococcus mutans’ adherence to two prevalent dental material surfaces, i.e., a cobalt–chromium(Co-Cr) alloy and a resin-based composite, under the influence of various sucrose concentrations. To understand bacterial adhesion, the surfaces were characterized using profilometry, tensiometry, and surface charge measurements. Bacterial adhesion was evaluated using scanning electron microscopy and crystal violet dye methods. Results revealed that the composite surface exhibited greater rough-ness compared with the Co-Cr alloy surface. Both surfaces displayed hydrophilic properties and a negative surface charge. Bacterial adhesion experiments indicated lower bacterial adherence to the Co-Cr alloy than to the composite surface before the addition of sucrose. However, the introduction of sucrose resulted in biofilm development on both surfaces, showcasing a similar increase in bacterial adhesion, with the highest levels being observed at a 5% sucrose concentration in the bacterial suspension. In conclusion, the findings suggest sucrose-rich foods could facilitate bacterial adaptation despite less favorable surface characteristics, thereby promoting biofilm formation.
Ključne besede: bacterial adhesion, streptococcus mutans, dental material surfaces, sucrose concentration
Objavljeno v DiRROS: 31.01.2024; Ogledov: 172; Prenosov: 65
Celotno besedilo (4,28 MB)
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24. LymphangioleiomyomatosisFranc Anderluh, 2002, pregledni znanstveni članek Povzetek: Background. Lymphangioleiomyomatosis is a rare disease of unknown origin, which affects women in their reproductive period. It is characterised by non-neoplastic proliferation of atypical smooth muscle cells in the lung parenchyma, lymphatic vessels and mediastinal and abdominal lymph nodes. The most common presenting symptoms are spontaneous pneumothorax, dyspnea, hemoptysis and chylothorax. Conclusions. High-resolution computed tomography (HRCT) and open lung biopsy followed by the immunohistologic studies are two diagnostic procedures with which diagnosis can be confirmed. Various treatmentmodalities are applied, particularly hormonal therapy, though their efficacy remain unknown. The prognosis of patients is bad.
Objavljeno v DiRROS: 31.01.2024; Ogledov: 146; Prenosov: 25
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25. Environment and breast cancer - the role of xenooestrogens in breast cancerAndrej Plesničar, Branko Družina, Viljem Kovač, Božo Kralj, 2002, izvirni znanstveni članek Povzetek: The survival rate of breast cancer patients has not changed much in the last few decades in developed countries. In order to improve the efficacy of breast cancer prevention and treatment, the role of xenooestrogens in the mechanisms of its development has been evaluated. These industrial chemical bear little structural resemblance to each other and bind to the oestrogen receptors of exposed cells and/or trigger oestrogenic responses in laboratory test systems. Exposure to xenooestrogens has been regarded as a risk factor for carcinogenesis and a preventable cause of breast carcinoma. Several epidemiological and experimental studies in in vivo and in vitro conditions of the influence of xenooestrogens on the occurrence of breast cancer have been conducted in the last decades and have shown ambiguous results. No increase of breast carcinoma incidence could be found in women who were exposed to relatively high concentrations of xenooestrogens for extended periods and small quantities of these compounds that are present in the environment probably cannot act as etiological agents for the occurence of this disease. A multi step approach is suggested regarding the sequence of studies and measures that should be taken to further assess the importance of xenooestrogens on breast cancer carcinogenesis.
Ključne besede: dojka, ksenoestrogeni, novotvorbe
Objavljeno v DiRROS: 31.01.2024; Ogledov: 127; Prenosov: 33
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26. Radical irradiation of the prostate. Combination of percutaneous irradiation and irradiation with LDR Ir-192 implantsBorut Kragelj, Franc Guna, Janez Burger, 2001, izvirni znanstveni članek Povzetek: Background. The irradiation of the carcinomas of the prostate with the doses above the tolerable ones of standard radiotherapy improves the local control of the disease. The aim of this study is to determine the acute toxicity and tolerability of the high-dose prostate irradiation combining external beam radiotherapy (EBRT) and interstitial low dose rate (LDR) brachyradiotherapy (BRT) Ir-192 of the prostate. Material and methods. We examined medical records of 8 patients with localized carcinoma of the prostate (T2-T3 No-x Mo)treated from August 1999 until February 2000. The initial PSA was 2.7-37.5 ng/ml (median 13.7) and Gleason score 4-9 (median 7). Radiotherapy consisted of 48.6-50.4 Gy of EBRT to the prostate and seminal vesicles (4 patients) or the whole pelvis (4 patients) and 20.0-28.0 Gy of interstital LDR Ir-192 BRT given as a single fraction, fluoroscopic guided transperineal Implantation of the prostate. The cumulative doses of percutaneous and interstitial irraditations to the prostate were 68.6 - 79.1 Gy. Results. Acute toxic effects of irradiation though observed in all patients were of only mild intensity. According to the RTOG criteria, 20/30 toxicities were assessed as grade 1, 9/30 as grade 2, and 1/30 as grade 3. In none of the patients, toxic effects required any specific modification of the treatment regimen. Conclusions. The very first experiences indicate moderate toxicity and optimaltolerance of the treatment by patients. An improvement of implantation techniques may be expected with regular CT controls of the implants and extra attentive care of the implants in the urethra region.
Objavljeno v DiRROS: 25.01.2024; Ogledov: 147; Prenosov: 35
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27. Resections of pelvic bone and sacrum, Ljubljana experienceJanez Novak, Marjana Čuček-Pleničar, Darja Eržen, Franc Srakar, Mojca Senčar, Boštjan Baebler, Jožica Červek, Alenka Vodnik-Cerar, Matej Bračko, Živa Pohar-Marinšek, Jožica Anžič, 1997, izvirni znanstveni članek Objavljeno v DiRROS: 16.01.2024; Ogledov: 181; Prenosov: 41
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30. Geološka spremljava poskusnega odkopa uranove rude na Žirovskem vrhuFranc Čadež, 2023, strokovni članek Povzetek: Leta 1981–1983 je bilo na Rudniku Žirovski vrh pred pričetkom redne proizvodnje izvedeno poskusno odkopavanje uranove rude za preverjanje metod geološke in radiometrične kontrole ter tehničnih metod pridobivanja. Poskusni odkop je bil v bloku 1, na skrajnem severozahodnem delu rudišča v zgornji gubi dvojne S strukture. V tem bloku se je orudenje nahajalo samo v horizontu sivega peščenjaka debeline 20–30 m. Z geološko spremljavo odkopavanja smo potrdili, da so bili peščenjaki odloženi v sekvencah debelih od par dm do več kot 2 m. Sekvenca je običajno pričenjala z debelozrnatim peščenjakom, večkrat so bili na bazi prisotni še klasti kremena in muljevca. Navzgor je debelozrnat peščenjak pogosto prehajal v srednjezrnatega, redkeje pa še v drobnozrnatega in meljevec. V peščenjakih je bila značilna prisotnost organskih drobcev, ki so v diagenezi ustvarjali redukcijsko okolje v katerem se je iz podtalnice izločal uran. Najpogosteje se je orudenje nahajalo v debelozrnatih peščenjakih, običajno v debelejših sekvencah. Orudenje se je zato pojavljalo v več nivojih debelih navadno pod 1m, kjer se je združevalo je skupna debelina presegla tudi 5 m. Dolžina sklenjenega orudenja v vzdolžni smeri je znašala do 150 m, širina od nekaj metrov do več kot 40 m. V vmesnih prekinitvah orudenja smo opazovali, da so peščenjaki iz temnosive in sive barve prehajali v svetlosive in zelenosive, ki so bili le siromašno orudeni ali jalovi. V vzdolžni smeri se je tak prehod zgodil med prerezi P-35 in P-35a, kjer se je tudi zaključilo odkopavanje. V jami sta bila raziskana še prereza P-36 in P-37, kjer pa se je pojavljal pretežno zelenosiv peščenjak z le redkimi lečami siromašnega orudenja. S površinskimi vrtinami sta bila dlje proti zahodu raziskana tudi še dva prereza oddaljena 1,3 in 2,8 km od jamske zgradbe. V teh vrtinah je bilo ugotovljeno nastopanje sivih in zelenosivih peščenjakov z zelo redkimi sledovi orudenja, ki so se menjavali z bolj drobnozrnatimi različki (muljevci), ostanki organske snovi pa so bili v njih zelo redki. Blok 1 je bil zato mejni blok na SZ strani rudišča, predviden za pridobivanje.
Ključne besede: uranova ruda, poskusno odkopavanje, grödenske klastične kamnine, Žirovski vrh
Objavljeno v DiRROS: 15.01.2024; Ogledov: 125; Prenosov: 35
Celotno besedilo (1,80 MB) |
