Digitalni repozitorij raziskovalnih organizacij Slovenije

Iskanje po repozitoriju
A+ | A- | Pomoč | SLO | ENG

Iskalni niz: išči po
išči po
išči po
išči po

Možnosti:
  Ponastavi


Iskalni niz: "avtor" (Ga��per��i�� Franc) .

11 - 20 / 243
Na začetekNa prejšnjo stran12345678910Na naslednjo stranNa konec
11.
Postoperative radiochemotherapy for gastric adenocarcinoma : long term results
Irena Oblak, Franc Anderluh, Vaneja Velenik, 2009, izvirni znanstveni članek

Povzetek: Background. To analyze the efficacy of postoperative radiochemotherapy with 5-florouracil (5-FU) and leucovorin (LV) applied in the patients with gastric carcinoma treated in a single institution. Patients and methods. Between 2001 and 2004, 123 patients with resected gastric adenocarcinoma were treated with postoperative concomitant radiochemotherapy with 5-FU and LV. The adjuvant treatment consisted of five cycles of chemotherapy with 5-FU (425mg/m2 IV) andLV (20 mg/m2 IV) and concomitant radiotherapy with the total dose of 45 Gy.Results. The treatment was completed according to the protocol in 82% of patients. The frequency and severity of early toxic effects induced by radiochemotherapy were manageable. Median follow-up time of 56 survivors was 64.5 months (range: 51.7-96.4 months). The 5-year locoregional control (LRC), diseasefree survival (DFS), disease-specific survival (DSS) and overall survival (OS) were 81%, 48.3%, 50.4%, and 48.4%, respectively. The multivariate analysis showed that the tumor involvement of cardia and low intensity of chemotherapy were independent adverse prognostic factors for DSS and OS. More advanced pT-stage and tumors with diffuse growth type according to Lauren were identified as negative independent prognostic factor for OS. They were also on the threshold of statistical significance for DSS. Conclusions. Postoperative radiochemotherapy for gastric carcinoma has acceptable toxicity, and is effective particularly in regard to LRC. High incidence of distant metastases calls for more effective systemic regimens.
Objavljeno v DiRROS: 08.03.2024; Ogledov: 63; Prenosov: 23
.pdf Celotno besedilo (94,49 KB)

12.
13.
Oka domains in Euclidean spaces
Franc Forstnerič, Erlend Fornæss Wold, 2024, izvirni znanstveni članek

Povzetek: In this paper, we find surprisingly small Oka domains in Euclidean spaces $\mathbb C^n$ of dimension $n>1$ at the very limit of what is possible. Under a mild geometric assumption on a closed unbounded convex set $E$ in $\mathbb C^n$, we show that $\mathbb C^n\setminus E$ is an Oka domain. In particular, there are Oka domains only slightly bigger than a halfspace, the latter being neither Oka nor hyperbolic. This gives smooth families of real hypersurfaces $\Sigma_t \subset \mathbb C^n$ for $t \in \mathbb R$ dividing $\mathbb C^n$ in an unbounded hyperbolic domain and an Oka domain such that at $t=0$, $\Sigma_0$ is a hyperplane and the character of the two sides gets reversed. More generally, we show that if $E$ is a closed set in $\mathbb C^n$ for $n>1$ whose projective closure $\overline E \subset \mathbb{CP}^n$ avoids a hyperplane $\Lambda \subset \mathbb{CP}^n$ and is polynomially convex in $\mathbb{CP}^n\setminus \Lambda\cong\mathbb C^n$, then $\mathbb C^n\setminus E$ is an Oka domain.
Ključne besede: Oka manifold, hyperbolic manifolds, density property, projectively convex sets
Objavljeno v DiRROS: 19.02.2024; Ogledov: 133; Prenosov: 48
.pdf Celotno besedilo (278,96 KB)
Gradivo ima več datotek! Več...

14.
Complete nonsingular holomorphic foliations on Stein manifolds
Antonio Alarcón, Franc Forstnerič, 2024, izvirni znanstveni članek

Povzetek: Let $X$ be a Stein manifold of complex dimension $n \ge 1$ endowed with a Riemannian metric ${\mathfrak g}$. We show that for every integer $k$ with $\left[\frac{n}{2}\right] \le k \le n-1$ there is a nonsingular holomorphic foliation of dimension $k$ on $X$ all of whose leaves are topologically closed and ${\mathfrak g}$-complete. The same is true if $1\le k \left[\frac{n}{2}\right]$ provided that there is a complex vector bundle epimorphism $TX\to X \times \mathbb{C}^{n-k}$. We also show that if $\mathcal{F}$ is a proper holomorphic foliation on $\mathbb{C}^n$ $(n > 1)$ then for any Riemannian metric ${\mathfrak g}$ on $\mathbb{C}^n$ there is a holomorphic automorphism $\Phi$ of $\mathbb{C}^n$ such that the image foliation $\Phi_*\mathcal{F}$ is ${\mathfrak g}$-complete. The analogous result is obtained on every Stein manifold with Varolin's density property.
Ključne besede: Stein manifolds, complete holomorphic foliations, density property
Objavljeno v DiRROS: 19.02.2024; Ogledov: 138; Prenosov: 46
.pdf Celotno besedilo (433,06 KB)
Gradivo ima več datotek! Več...

15.
Breast cancer and breast health awareness as an evolving health promotion concept
Andrej Plesničar, Viljem Kovač, Božo Kralj, 2004, izvirni znanstveni članek

Povzetek: Background. Breast cancer is the most frequent malignant disease in the majority of developed countries. In the last few years the introduction of mammography screening programmes has resulted in an improved survival of breast cancer patients. However, the incidence of the disease in these countries is still on the increase. Present focus on secondary breast cancer prevention activities, consisting of early detection and treatment, cannot ensure a decrease of breast cancer incidence. Improved breast health awarenesscould therefore represent a part of specific health promotion activities aimed at decreasing the incidence of breast cancer. Conclusions. Indeveloped countries breast cancer is a significant health care issue. Secondary breast cancer prevention activities should therefore be complementedby specific health promotion activities in order to reduce its incidence in the future. Primary breast cancer prevention would include healthpromotion activities aimed at enhancement of the individual as well as collective breast health awareness. Properly enlightened members of the influential population groups could attain appropriate changes in the fields of legislation, taxation, customs and commercial regulations that would enablewomen to control their own breast health.
Objavljeno v DiRROS: 07.02.2024; Ogledov: 133; Prenosov: 29
.pdf Celotno besedilo (84,20 KB)

16.
Calculation of deformation-related quantities in a hot-rolling process
Franci Vode, Simon Malej, Franc Tehovnik, Boštjan Arh, Bojan Podgornik, 2023, izvirni znanstveni članek

Objavljeno v DiRROS: 02.02.2024; Ogledov: 115; Prenosov: 46
.pdf Celotno besedilo (1,39 MB)
Gradivo ima več datotek! Več...

17.
Dispersoids in Al-Mg-Si alloy AA 6086 modified by Sc and Y
Franc Zupanič, Sandi Žist, Mihaela Albu, Ilse Letofsky-Papst, Jaka Burja, Maja Vončina, Tonica Bončina, 2023, izvirni znanstveni članek

Ključne besede: aluminium alloy, heat treatment, microstructure, dispersoids, dilatometry, DSC, hardness
Objavljeno v DiRROS: 02.02.2024; Ogledov: 116; Prenosov: 58
.pdf Celotno besedilo (11,03 MB)
Gradivo ima več datotek! Več...

18.
Effect of sucrose concentration on streptococcus mutans adhesion to dental material surfaces
Anamarija Zore, Franc Rojko, Nives Matijaković Mlinarić, Jona Veber, Aleksander Učakar, Roman Štukelj, Andreja Pondelak, Andrijana Sever Škapin, Klemen Bohinc, 2024, izvirni znanstveni članek

Povzetek: Enamel demineralization, known as dental caries, is instigated by the bacterium Streptococcus mutans, which generates acid during carbohydrate metabolism. Among carbohydrates, sucrose is the most cariogenic and capable of biofilm formation. This study aimed to explore and comprehend Streptococcus mutans’ adherence to two prevalent dental material surfaces, i.e., a cobalt–chromium(Co-Cr) alloy and a resin-based composite, under the influence of various sucrose concentrations. To understand bacterial adhesion, the surfaces were characterized using profilometry, tensiometry, and surface charge measurements. Bacterial adhesion was evaluated using scanning electron microscopy and crystal violet dye methods. Results revealed that the composite surface exhibited greater rough-ness compared with the Co-Cr alloy surface. Both surfaces displayed hydrophilic properties and a negative surface charge. Bacterial adhesion experiments indicated lower bacterial adherence to the Co-Cr alloy than to the composite surface before the addition of sucrose. However, the introduction of sucrose resulted in biofilm development on both surfaces, showcasing a similar increase in bacterial adhesion, with the highest levels being observed at a 5% sucrose concentration in the bacterial suspension. In conclusion, the findings suggest sucrose-rich foods could facilitate bacterial adaptation despite less favorable surface characteristics, thereby promoting biofilm formation.
Ključne besede: bacterial adhesion, streptococcus mutans, dental material surfaces, sucrose concentration
Objavljeno v DiRROS: 31.01.2024; Ogledov: 128; Prenosov: 52
.pdf Celotno besedilo (4,28 MB)
Gradivo ima več datotek! Več...

19.
Lymphangioleiomyomatosis
Franc Anderluh, 2002, pregledni znanstveni članek

Povzetek: Background. Lymphangioleiomyomatosis is a rare disease of unknown origin, which affects women in their reproductive period. It is characterised by non-neoplastic proliferation of atypical smooth muscle cells in the lung parenchyma, lymphatic vessels and mediastinal and abdominal lymph nodes. The most common presenting symptoms are spontaneous pneumothorax, dyspnea, hemoptysis and chylothorax. Conclusions. High-resolution computed tomography (HRCT) and open lung biopsy followed by the immunohistologic studies are two diagnostic procedures with which diagnosis can be confirmed. Various treatmentmodalities are applied, particularly hormonal therapy, though their efficacy remain unknown. The prognosis of patients is bad.
Objavljeno v DiRROS: 31.01.2024; Ogledov: 115; Prenosov: 18
.pdf Celotno besedilo (76,06 KB)

20.
Environment and breast cancer - the role of xenooestrogens in breast cancer
Andrej Plesničar, Branko Družina, Viljem Kovač, Božo Kralj, 2002, izvirni znanstveni članek

Povzetek: The survival rate of breast cancer patients has not changed much in the last few decades in developed countries. In order to improve the efficacy of breast cancer prevention and treatment, the role of xenooestrogens in the mechanisms of its development has been evaluated. These industrial chemical bear little structural resemblance to each other and bind to the oestrogen receptors of exposed cells and/or trigger oestrogenic responses in laboratory test systems. Exposure to xenooestrogens has been regarded as a risk factor for carcinogenesis and a preventable cause of breast carcinoma. Several epidemiological and experimental studies in in vivo and in vitro conditions of the influence of xenooestrogens on the occurrence of breast cancer have been conducted in the last decades and have shown ambiguous results. No increase of breast carcinoma incidence could be found in women who were exposed to relatively high concentrations of xenooestrogens for extended periods and small quantities of these compounds that are present in the environment probably cannot act as etiological agents for the occurence of this disease. A multi step approach is suggested regarding the sequence of studies and measures that should be taken to further assess the importance of xenooestrogens on breast cancer carcinogenesis.
Ključne besede: dojka, ksenoestrogeni, novotvorbe
Objavljeno v DiRROS: 31.01.2024; Ogledov: 106; Prenosov: 26
.pdf Celotno besedilo (96,95 KB)

Iskanje izvedeno v 0.38 sek.
Na vrh