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1.
Cysteine proteinase inhibitors stefin A and stefin B in operable carcinoma of the head and neck : Inhibitorji cisteinskih proteinaz stefin A in stefin B pri operabilnem karcinomu glave in vratu
Primož Strojan, Marjan Budihna, Alojz Šmid, Branka Svetic, Ivan Vrhovec, Janko Kos, Janez Škrk, 2002, izvirni znanstveni članek

Povzetek: Purpose. To evaluate the significance of cysteine proteinase inhibitors stefins (Stefs) A and B for a treatment decision and prognosis in operable squamous cell carcinoma of the head and neck (SCCHN). Patients and methods. Stefs A and B concentrations were determined immunobiochemically using ELISAs in cytosols prepared from the tumor and adjacent normal mucosa from 91 patients with operable SCCHN. The median follow-up period of patients alive atthe close-out date was 5.8 years (range, 5-9.3 years). Results. Stef A concentrations were significantly higher in tumor compared to normal mucosa (FM.05). When a subgroup with clinically palpable nodes) at presentation was taken into consideration (n=57), a significant difference in Stef A (P=0.03) and Stef B (P=0.02) concentrations between those with negative and positive necks, as determined on histopathological examination, was observed. On the univariate survival analysis, higher Stefsć concentrations turned to be prognostically advantageous. Stef A proved its independent prognostic significance also on multivariate setting. Conclusions. With the capability todifferentiate between the pN0- and pN+-stages of the disease in the patientsoriginally presented as node-positive, Stefs A and B could be useful markers when deciding on the extent of neck surgery. In addition, both Stefs proved to be reliable prognosticators for survival in patients with operable SCCHN.
Objavljeno v DiRROS: 31.01.2024; Ogledov: 119; Prenosov: 29
.pdf Celotno besedilo (114,91 KB)

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Cathepsin H in squamous cell carcinoma of the head and neck
Primož Strojan, Marjan Budihna, Alojz Šmid, Branka Svetic, Ivan Vrhovec, Janko Kos, Janez Škrk, 1999, izvirni znanstveni članek

Objavljeno v DiRROS: 22.01.2024; Ogledov: 134; Prenosov: 36
.pdf Celotno besedilo (557,02 KB)

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Superficial thermoradiotherapy: clinical result favor immediate irradiation prior to hyperthermia
Hotimir Lešničar, Marjan Budihna, 1997, izvirni znanstveni članek

Ključne besede: Neoplasms, local advanced
Objavljeno v DiRROS: 17.01.2024; Ogledov: 151; Prenosov: 39
.pdf Celotno besedilo (607,22 KB)

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Preface
Tanja Čufer, Marjan Budihna, 1997, predgovor, uvodnik, spremna beseda

Objavljeno v DiRROS: 16.01.2024; Ogledov: 114; Prenosov: 36
.pdf Celotno besedilo (40,23 KB)

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Linearno-kvadratični model frakcioniranja u radioterapijskoj primjeni
M... Bistrović, Marjan Budihna, E... Čepulić, Marko Habič, Z... Kuzmanović, Janez Škrk, 1989, pregledni znanstveni članek

Objavljeno v DiRROS: 15.09.2023; Ogledov: 409; Prenosov: 59
.pdf Celotno besedilo (1,91 MB)

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