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44. Pregled, izbira in analiza lesnih vrst : Rezultat D1.1.1 (M24, dokument)Luka Krajnc, Polona Hafner, Andreja Vedenik, Jožica Gričar, Primož Simončič, 2020, treatise, preliminary study, study Keywords: les, leseni izdelki, indikatorji kakovosti lesa, gostota lesa
Published in DiRROS: 09.04.2021; Views: 1265; Downloads: 76
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46. Content analysis of Advance Directives completed by patients with advanced cancer as part of an Advance Care Planning intervention : insights gained from the ACTION trialMarieke Zwakman, Johannes JM van Delden, Glenys Caswell, Luc Deliens, F. Ingravallo, Lea J. Jabbarian, Anna Thit Johnsen, Ida Joanna Korfage, Alenka Mimič, C. Møller Arnfeldt, Urška Lunder, Branka Červ, Anja Simonič, Hana Kodba Čeh, Polona Ozbič, 2019, original scientific article Abstract: Purpose. Writing an Advance Directive (AD) is often seen as a part of Advance Care Planning (ACP). ADs may include specific preferences regarding future care and treatment and information that provides a context for healthcare professionals and relatives in case they have to make decisions for the patient. The aim of this study was to get insight into the content of ADs as completed by patients with advanced cancer who participated in ACP conversations. Methods. A mixed methods study involving content analysis and descriptive statistics was used to describe the content of completed My Preferences forms, an AD used in the intervention arm of the ACTION trial, testing the effectiveness of the ACTION Respecting Choices ACP intervention. Results. In total, 33% of 442 patients who received the ACTION RC ACP intervention completed a My Preferences form. Document completion varied per country: 10.4% (United Kingdom), 20.6% (Denmark), 29.2% (Belgium), 41.7% (the Netherlands), 61.3% (Italy) and 63.9% (Slovenia). Content analysis showed that 'maintaining normal life' and 'experiencing meaningful relationships' were important for patients to live well. Fears and worries mainly concerned disease progression, pain or becoming dependent. Patients hoped for prolongation of life and to be looked after by healthcare professionals. Most patients preferred to be resuscitated and 44% of the patients expressed maximizing comfort as their goal of future care. Most patients preferred 'home' as final place of care. Conclusions. My Preferences forms provide some insights into patients' perspectives and preferences. However, understanding the reasoning behind preferences requires conversations with patients.
Keywords: advance care planning, psycho-oncology, medical oncology, ACTION study, cancer, end of life, dying persons
Published in DiRROS: 15.02.2021; Views: 1271; Downloads: 884
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47. Decrease in cellular nanovesicles concentration in blood of athletes more than 15 hours after marathonZala Jan, Mitja Drab, Damjana Drobne, Apolonija Bedina Zavec, Mojca Benčina, Barbara Drašler, Matej Hočevar, Judita Lea Krek, Ljubiša Pađen, Manca Pajnič, Neža Repar, Boštjan Šimunič, Roman Štukelj, Veronika Kralj-Iglič, 2021, original scientific article Abstract: Introduction: Cellular nanovesicles (CNVs), that are shed from cells, have been recognized as promising indicators of health status. We analyzed the effect of long-distance running on concentration of CNVs, along with some standard blood parameters, in 27 athletes two days before and > 15 hours after physical effort. Methods: CNVs were isolated by repetitive centrifugation and washing of samples, and assessed by flow cytometry. Cholinesterase (ChE) and glutathione S-transferase (GST) activity were measured spectrophotometrically. Interleukin 6 (IL-6) and tumor necrosis factor-% (TNF-%) concentrations were measured using enzyme-linked immunosorbent assay (ELISA). C-reactive protein (CRP) was measured with immunoturbidimetric determination and lipidogram parameters were measured by enzymatic colorimetric assay. Flow cytometry was used for blood cell count and mean platelet volume (MPV) measurement. Results: More than 15 hours after physical effort a decrease was found in CNVs% concentration in isolates from blood (46%; p< 0.05), in ChE activity in whole blood (47%; p< 0.001), in plasma (34%; p< 0.01), and in erythrocyte suspension (54%; p< 0.001), as well as in GST activity in erythrocyte suspension (16%; p< 0.01) and in IL-6 concentration in plasma (63%; p< 0.05). We found no change in GST activity in plasma and in TNF-% concentration in plasma. Correlations (> 0.8; p< 0.001) between CNVs% concentration and ChE activity, and GST activity, respectively, in erythrocyte suspension were found. Conclusion: We found that > 15 hours post-physical effort, CNVs% concentration was below the initial value, concomitant with other measured parameters: ChE and GST activity as well as IL-6 concentration, indicating a favorable effect of physical effort on health status. CNVs% concentration and ChE activity in isolates from peripheral blood proved to have potential as indicators of the response of the human body to inflammation after physical effort. Physical activity should be considered as an important factor in preparation of subjects for blood sampling in procedures focusing on CNV-containing diagnostic and therapeutic compounds.
Keywords: membrane vesiculation, physical effort, blood samples, inflammation process, cellular nanovesicles, marathon
Published in DiRROS: 25.01.2021; Views: 1275; Downloads: 1588
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48. The effect of bedrock and species mixture on wood density and radial wood increment in pubescent oak and black pineLuka Krajnc, Polona Hafner, Jožica Gričar, 2020, original scientific article Abstract: Wood density and radial wood increment were examined in trees of pubescent oak (Quercus pubescens Willd.) and black pine (Pinus nigra Arnold., subsp. nigra) in relation to stand mixture and underlying bedrock. Trees of both species from pure and mixed stands were sampled across two types of bedrock, limestone and flysch. Trees from each species were similar in age. Wood density was estimated in standing trees using resistance drilling and increment cores were taken from a smaller subsample of trees of both species. Tree-ring, earlywood and latewood widths were measured and compared to radial profiles of wood density. The influence of stand mixture, diameter at breast height and bedrock on wood density was examined using a Bayesian general linear model. Wood density was significantly higher in pubescent oak than in black pine. Stand mixture was found to affect wood density positively, although the magnitude of the effect was relatively small when compared to other influencing factors also included in the current study. The effect of diameter on wood density was positive on both bedrocks in pubescent oak and negative or neutral in black pine. The size of the effect varied by bedrock and species. On flysch bedrock, the influence of diameter on wood density was stronger than it was on limestone. These indirect bedrock effects on wood density are probably a result of different soil fertility rather than the bedrock itself. There was a notable difference in radial wood increment in both species across the two bedrocks, whereas the differences in densities were smaller. Higher wood densities found on flysch in the subsample of pubescent oaks are likely an effect of higher proportions of latewood, while the opposite trend was observed in black pine. Higher wood density was found on limestone in black pine despite higher latewood percentages on flysch. In the context of forest management, the species composition of the naturally occurring mixtures in the sub-Mediterranean region should be adjusted slightly to favor pubescent oak, since it is a climax species and will bind more carbon for longer than black pine due to higher wood densities. Future forest management should also promote the overall development of pubescent oak trees in sub-Mediterranean stands. The results are especially important in the European context, because the share of sub-Mediterranean stands is expected to rise with global warming.
Keywords: Karst, wood structure, resistograph, resistance drilling, Quercus pubescens, Pinus nigra, limestone, flysch
Published in DiRROS: 14.01.2021; Views: 1106; Downloads: 377
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50. Umerjanje rezistografskih meritev gostote lesa na stoječih drevesih : pretvorba v osnovno gostotoLuka Krajnc, Polona Hafner, Jožica Gričar, Primož Simončič, 2020, short scientific article Abstract: V prispevku predstavljamo proces in rezultate določitve korekcijskih količnikov za pretvorbo rezistografskih gostot, izmerjenih na stoječih drevesih, v osnovno gostoto lesa na primeru bukve (Fagus sylvatica L.), puhastega hrasta (Quercus pubescens Willd.) in črnega bora (Pinus nigraArnold.). Korekcijski količniki so bili določeni na podlagi sveže odžaganih kolutov, ki so bili povrtani z rezistografom. Kolute smo stehtali, izmerili njihovo prostornino ter jih posušili do absolutno suhega stanja. Iz zbranih podatkov smo nato izračunali osnovno gostoto lesa ter korekcijske količnike med osnovno in rezistografsko gostoto. V raziskavo je bilo zajetih 59 kolutov. Aritmetična sredina vseh izmerjenih količnikov znaša 1,41, vrednosti 95 % intervala zaupanja pa znašajo od 1,38 do 1,46. Razlike med drevesnimi vrstami so statistično neznačilne. Rezistografska gostota relativno dobro odraža osnovno gostoto kolutov (Pearsonov korelacijski koeficient = 0,91; p < 0,001), kar nakazuje na relativno dobro povezanost osnovnih gostot kolutov z rezistografskimi gostotami. Dobljeni rezultati so ključnega pomena za nadaljnji razvoj področja merjenja dejanskih gostot lesa v stoječih drevesih na hiter in relativno nedestruktiven način.
Keywords: rezistograf, gostota lesa, kakovost lesa, bukev, puhasti hrast, črni bor
Published in DiRROS: 14.12.2020; Views: 1685; Downloads: 468
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