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471.
472.
Co-opeative effects in tumorigenicity. The microcystin example
Bojan Sedmak, Dušan Šuput, 2002, short scientific article

Published in DiRROS: 31.01.2024; Views: 113; Downloads: 25
.pdf Full text (169,97 KB)

473.
474.
Ultra-high strenght TWIP steel with high chromium content
Pavel Podaný, Tomáš Studecký, Tomas Gregor, Radek Prochazka, Aleksandra Kocijan, 2023, original scientific article

Abstract: A new ultra-high strength steel with a fully austenitic microstructure and twinning-induced plasticity (TWIP) effect has been developed. TWIP effect gives this steel a good combination of high strength of over 1000 MPa and ductility of over 35%. This new steel has a high chromium content, which increases its corrosion resistance. By combining cold rolling and annealing, the steel has achieved a very fine austenitic microstructure with an average grain diameter of 2.85 µm. This steel could be used for structural applications or components that need to withstand high levels of stress, deformation and corrosion environment.
Keywords: TWIP steels, corrosion resistance, microstructure, tensile strength, plasticity
Published in DiRROS: 31.01.2024; Views: 146; Downloads: 53
.pdf Full text (1,44 MB)
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475.
Cadmium induced DNA damage in human hepatoma (Hep G2) and Chinese hamster ovary (CHO) cells
Tanja Fatur, Metka Filipič, 2002, short scientific article

Published in DiRROS: 31.01.2024; Views: 109; Downloads: 22
.pdf Full text (95,67 KB)

476.
Genetic toxicology: from exposure detection to cancer prevention
Metka Filipič, 2002, other component parts

Published in DiRROS: 31.01.2024; Views: 133; Downloads: 23
.pdf Full text (49,97 KB)

477.
Magnetic resonance spectroscopy: an overview of the method and its applicationin clinical neuroradiology
Aleš Koren, 2002, original scientific article

Abstract: Background. Magnetic resonance spectroscopy (MRS) is a comparatively new diagnostic method. Brain tissue is very suitable for MRS analysis. In practice, only a small number of compounds present in the brain may be analysed by MRS. The utility of MRS in neuroradiology and clinical practice isconstantly growing since the investigation is of help in the differential diagnosis of pathological processes as well as in assessing the progress of a disease and evaluating the outcome of treatment. In analysing the data obtained, a number of factors that may influence the objectivity of the resultmust be taken into account. The magnetic resonance scanner located at the Institute of Radiology, University Medical Centre Ljubljana, utilises modern MRS protocols and has proved a valuable tool in the diagnostic evaluation of neurologic diseases. Conclusions. MRS provides spectral analysisof substance in a selected volume of tissue, thereby offering an insight into the metabolic state of the tissue.
Published in DiRROS: 31.01.2024; Views: 125; Downloads: 28
.pdf Full text (110,16 KB)

478.
Gastroparesis in a young diabetic patient
Primož Kovačič, Breda Jamar, 2002, original scientific article

Abstract: Background. Gastroparesis is defined as a delay in emptying of contents from the stomach and occurs in a variety of conditions, e.g. after vagotomy or in systemic diseases such as diabetes mellitus, scleroderma and amyloidosis. The purpose of this paper is to present the radiologic examination, a simple, reliable and noninvasive method as an alternative to other methods for the assessment of gastric emptying. Case report. A twenty-one years old female wasadmitted because of suspected autonomic neuropathy. She had insulin dependent diabetes mellitus type 1 for the last ten years. At the time of admission she was complaining of nausea, vomiting weakness and occasional dizziness. A barium study of oesophagus and stomach was performed: oesophagus was dilated and aperistaltic, remnants of food were seen in aperistaltic stomach but no obstruction, causing delayed emptying, was found. Conclusions. Scintigraphy is at the present the standard technique for the assessment of gastric emptying. Ultrasonography, magnetic resonance imaging; electrogastrography, gastroduodenal manometry and emptying of radiopaque pellets are also used for the evaluation of gastric motility in cases of delayed gastric emptying. The role of barium studies remains to be established.
Published in DiRROS: 31.01.2024; Views: 101; Downloads: 27
.pdf Full text (79,86 KB)

479.
Improving the surface properties of additive-manufactured Inconel 625 by plasma nitriding
Danijela Anica Skobir Balantič, Črtomir Donik, Bojan Podgornik, Aleksandra Kocijan, Matjaž Godec, 2023, original scientific article

Abstract: As a surface-hardening technique, plasma nitriding is a common procedure for improving the properties of conventional Ni-based alloys. The diffusion of nitrogen hardens a layer on the surface of the alloy, leading to better wear resistance and a higher coefficient of friction, as well as a higher surface hardness. This study reports the effect of plasma nitriding on additive-manufactured (AM) Inconel 625 (IN625) compared to its conventional manufactured and nitrided counterparts. The samples produced with the laser powder-bed fusion (LPBF) process were subsequently plasma nitrided in the as-built condition, stress-relief annealed at 870 °C and solution treated at 1050 °C. The plasma nitridings were carried out at 430 °C and 500 °C for 15 h. The growth kinetics of the nitride layer of the AM samples depends on the prior heat treatments and is faster in the as-built state due to the specific cellular structure. The lower nitriding temperature leads to the formation of expanded austenite in the nitride layer, while at the higher nitriding temperature, the expanded austenite decomposes and CrN precipitation occurs. The XRD and SEM analyses confirmed the presence of two layers: the surface layer and the diffusion layer beneath. The lower nitriding temperature caused the formation of expanded austenite or a combination of expanded austenite and CrN. The higher nitriding temperature led to the decomposition of the expanded austenite and to the formation/precipitation of CrN. The higher nitriding temperature also decreased the corrosion resistance slightly due to the increased number of precipitated Cr-nitrides. On the other hand, the wear resistance was significantly improved after plasma nitriding and was much less influenced by the nitriding temperature.
Keywords: additive manufacturing, powder-bed fusion, plasma nitriding, expanded austenite, wear and corrosion resistance, Ni-based alloy
Published in DiRROS: 31.01.2024; Views: 148; Downloads: 57
.pdf Full text (7,98 MB)
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480.
A brief overview of the tumor vaccines through the last decade
Srdjan Novaković, Barbara Jezeršek Novaković, 2002, review article

Abstract: How to destroy cancer cells without damaging the normal cells? How to make conventional methods of systemic cancer treatment that predominantly comprise cytotoxic drugs more selective and prevent the development of drug resistance?There is an abundance of such guestions that do not have simple answers. If, a few years ago, unselective cytotoxic drugs were the method of choice for the treatment of cancer, in the last 25 years we are witnessing therapid transition of immunotherapy from the laboratories to the clinics. Among the most attractive and promising immunotherapies for cancer, a special place is reserved for tumor vaccines. Exploiting the latest knowledge in immunology, tumor physiology, as well as in molecular biology, many outstanding approaches for the creation of tumor vaccines have been developed.With no intention to be comprehensive, in the present article some of those approaches are reviewed.
Published in DiRROS: 31.01.2024; Views: 131; Downloads: 28
.pdf Full text (97,46 KB)

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