1. Evaluating plant growth–defense trade-offs by modelingthe interaction between primary and secondary metabolismJan Zrimec, Sandra Correo, Maja Zagorščak, Marko Petek, Carissa Bleker, Katja Stare, Christian Schuy, Sophia Sonnewald, Kristina Gruden, Zoran Nikoloski, 2025, izvirni znanstveni članek Povzetek: Understanding the molecular mechanisms behind plant response to stress can enhancebreeding strategies and help us design crop varieties with improved stress tolerance,yield, and quality. To investigate resource redistribution from growth- to defense-relatedprocesses in an essential tuber crop, potato, here we generate a large-scale compartmen-talized genome-scale metabolic model (GEM), potato-GEM. Apart from a large-scalereconstruction of primary metabolism, the model includes the full known potato sec-ondary metabolism, spanning over 566 reactions that facilitate the biosynthesis of 182distinct potato secondary metabolites. Constraint-based modeling identifies that theactivation of the largest amount of secondary (defense) pathways occurs at a decreaseof the relative growth rate of potato leaf, due to the costs incurred by defense. We thenobtain transcriptomics data from experiments exposing potato leaves to two bioticstress scenarios, a herbivore and a viral pathogen, and apply them as constraints toproduce condition-specific models. We show that these models recapitulate experimen-tally observed decreases in relative growth rates under treatment as well as changes inmetabolite levels between treatments, enabling us to pinpoint the metabolic rewiringunderlying growth–defense trade-offs. Potato- GEM thus presents a useful resource tostudy and broaden our understanding of potato and general plant defense responsesunder stress conditions.
Ključne besede: systems biology, constraint-based metabolic modeling, growth-defence trade-offs, secondary metabolism
Objavljeno v DiRROS: 24.09.2025; Ogledov: 587; Prenosov: 219
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2. Phloem : a missing link in understanding tree growth response in a changing environmentJožica Gričar, 2024, izvirni znanstveni članek Povzetek: Although the activities of various tree organs and tissues are under different environmental and internal constraints, they need to be coordinated to ensure whole-tree functioning. Dusart et al. (2024) conducted a heating experiment on branches of Juglans regia saplings during the entire growing season to examine the effect of temperature on primary (bud) and secondary (xylem) growth. They found that primary and secondary meristems responded asynchronously to elevated temperature, which suggests that lack of coordination mechanisms between primary and secondary growth at crown scale could have a potential impact on canopy and tree architecture.
Ključne besede: phloem, wood anatomy, tree growth, angiosperms, bark, meristem, non-structural carbohydrates, primary growth, radial growth, secondary growth, temperature, xylem
Objavljeno v DiRROS: 05.12.2024; Ogledov: 783; Prenosov: 625
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