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1.
Ecotoxicologically relevant cyclic peptides from cyanobacterial bloom (Planktothrix rubecens) - a threat to human and environmental health
Bojan Sedmak, Tina Eleršek, Olga Grach-Pogrebinsky, Shmuel Carmeli, Nataša Sever, Tamara Lah Turnšek, 2008, izvirni znanstveni članek

Povzetek: Background. The information of the overall production of major cyanobacterial cyclic peptides in a water body is essential for risk assessment and for the prediction of future development of the bloom. A procedure that gives a reviewof both toxic and non-hepatotoxic hydrophilic cyclic peptide production is important to evaluate the ecological conditions in the water environment and to predict the release of dangerous toxic and tumour promoting substances.Methods. The cyclic peptides were identified on the basis of their retention times, characteristic spectra, molecular masses and biological activity. The non-hepatotoxic cyclic peptides were characterised by their inhibition of porcine pancreatic elastase, while cytotoxicity to mammalian cells was tested with the MTT test on B16 cell line. Conclusions. The method presented gives a rapid, simultaneous assessment, preliminary identification and estimation of bioactive cyclic peptides. The synthesis of non-hepatotoxic cyclic peptides can mediate the release various toxic and otherwise biologically active substances that induce systemic genotoxicity in mammals.
Ključne besede: tumor promoters, microcystin, anabaenopeptin, planktopeptin, toxic cyanobacterial blooms, environmental health
Objavljeno v DiRROS: 07.03.2024; Ogledov: 83; Prenosov: 13
.pdf Celotno besedilo (286,29 KB)

2.
Comprehensive permanent remote monitoring system of a multi-span highway bridge
Andrej Anžlin, Uroš Bohinc, Doron Hekič, Maja Kreslin, Jan Kalin, Aleš Žnidarič, 2021, objavljeni znanstveni prispevek na konferenci

Povzetek: As part of the reconstruction of a multi-span viaduct on a Slovenian highway, a permanent remote monitoring system with over 200 sensors was established. Several parameters are monitored on different parts of the viaduct by means of temperature sensors, accelerometers, strain gauges, long-gauge deformation and Fibre Bragg Grating (FBG) sensors. In this way strains, frequencies and temperatures on external prestressed beam cables, carbon fibre rebarsused for the flexural strengthening of a deck overhang, pier caps and prestressed beams are measured and stored into the on-site central data acquisition system. This paper presents architecture of the permanent bridge monitoring system and preliminary results of the measurements.
Ključne besede: permanent monitoring, structural health monitoring, bridge WIM, sensors, viaduct
Objavljeno v DiRROS: 22.01.2024; Ogledov: 192; Prenosov: 97
.pdf Celotno besedilo (9,29 MB)
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3.
Using statistical analysis of an acceleration-based bridge weigh-in-motion system for damage detection
Eugene J. O'Brien, Muhammad Arslan Khan, Daniel Patrick McCrum, Aleš Žnidarič, 2020, izvirni znanstveni članek

Povzetek: This paper develops a novel method of bridge damage detection using statistical analysis of data from an acceleration-based bridge weigh-in-motion (BWIM) system. Bridge dynamic analysis using a vehicle-bridge interaction model is carried out to obtain bridge accelerations, and the BWIM concept is applied to infer the vehicle axle weights. A large volume of traffic data tends to remain consistent (e.g., most frequent gross vehicle weight (GVW) of 3-axle trucks); therefore, the statistical properties of inferred vehicle weights are used to develop a bridge damage detection technique. Global change of bridge stiffness due to a change in the elastic modulus of concrete is used as a proxy of bridge damage. This approach has the advantage of overcoming the variability in acceleration signals due to the wide variety of source excitations/vehicles–data from a large number of different vehicles can be easily combined in the form of inferred vehicle weight. One year of experimental data from a short-span reinforced concrete bridge in Slovenia is used to assess the effectiveness of the new approach. Although the acceleration-based BWIM system is inaccurate for finding vehicle axle-weights, it is found to be effective in detecting damage using statistical analysis. It is shown through simulation as well as by experimental analysis that a significant change in the statistical properties of the inferred BWIM data results from changes in the bridge condition.
Ključne besede: bridge health monitoring, bridge WIM, structural dynamics, damage detection, vehicle-bridge interaction
Objavljeno v DiRROS: 12.09.2023; Ogledov: 235; Prenosov: 123
.pdf Celotno besedilo (8,01 MB)
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4.
Functional characteristics and subjective disease perception in patients with COVID-19 two months after hospital discharge
Kaja Teraž, Boštjan Šimunič, Manca Peskar, Uroš Marušič, Saša Pišot, Luka Šlosar, Mladen Gasparini, Rado Pišot, 2023, izvirni znanstveni članek

Povzetek: Introduction: Although early inpatient and post-hospital rehabilitation is recognized as necessary, not all COVID-19 patients have access to rehabilitation. There are no published reports in the literature that investigate the outcomes of patients who do not receive rehabilitation after COVID-19. Our aim was to evaluate possible improvements in determinate functional and psychological parameters in COVID19 patients two months after their hospital discharge. Methods: On both time points various motor, cognitive, and clinical measurements such as body composition, tensiomyography, blood pressure, spirometry, grip strength test, Timed Up and Go test, gait speed, 30-second chair-stand test, and Montreal Cognitive Assessment, were performed. Additionally, questionnaires such as the SARC-CalF test, Edmonton frail scale, International Physical Activity questionnaire andThe Mediterranean Lifestyle index were conducted to assess lifestyle characteristics. Results: A total of 39 patients (87.2% male; mean age of 59.1 ± 10.3 years), who were hospitalized due to COVID-19 at the Izola General Hospital (IGH), Slovenia between December 2020 and April 2021, were included. Patients were assessed at two time points (T1 and T2): T1 was taken after receiving a negative COVID-19 test and T2 was taken two months after T1. After two months of self-rehabilitation, we have detected a BMI increase (p < .001), fat free mass increase (p < .001), better Edmonton frail scale (p < .001), SARC-CalF score (p = .014) and MoCA score (p = .014). There were no detected changes in lifestyle habits nor in physical performance tests. Discussion: It is already known that COVID-19 has long-term negative consequences regardless of the stage of the disease. Our findings support the notion that patients cannot fully regain all their functions within a two-month period without receiving structured or supervised rehabilitation. Therefore, it is crucial to offer patients comprehensive and structured rehabilitation that incorporates clinical, cognitive, and motor exercises.
Ključne besede: pandemics, coronavirus, functional improvement, hospital stay, health perception
Objavljeno v DiRROS: 26.07.2023; Ogledov: 307; Prenosov: 148
.pdf Celotno besedilo (892,24 KB)
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5.
Model updating concept using bridge Weigh-in-Motion data
Doron Hekič, Andrej Anžlin, Maja Kreslin, Aleš Žnidarič, Peter Češarek, 2023, izvirni znanstveni članek

Povzetek: Finite element (FE) model updating of bridges is based on the measured modal parameters and less frequently on the measured structural response under a known load. Until recently, the FE model updating did not consider strain measurements from sensors installed for weighing vehicles with bridge weigh-in-motion (B-WIM) systems. A 50-year-old multi-span concrete highway viaduct, renovated between 2017 and 2019, was equipped with continuous monitoring system with over 200 sensors, and a B-WIM system. In the most heavily instrumented span, the maximum measured longitudinal strains induced by the full-speed calibration vehicle passages were compared with the modelled strains. Based on the sensitivity study results, three variables that affected its overall stiffness were updated: Young’s modulus adjustment factor of all structural elements, and two anchorage reduction factors that considered the interaction between the superstructure and non-structural elements. The analysis confirmed the importance of the initial manual FE model updating to correctly reflect the non-structural elements during the automatic nonlinear optimisation. It also demonstrated a successful use of pseudo-static B-WIM loading data during the model updating process and the potential to extend the proposed approach to using random B-WIM-weighed vehicles for FE model updating and long-term monitoring of structural parameters and load-dependent phenomena.
Ključne besede: monitoring, bridge, viaduct, bridge weigh-in-motion (B-WIM), structural health monitoring (SHM), finite element (FE), calibration, model updating
Objavljeno v DiRROS: 29.05.2023; Ogledov: 373; Prenosov: 195
.pdf Celotno besedilo (26,28 MB)
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6.
Exploring the well-being of Slovenian and Serbian sport science students during the covid-19 pandemic of summer 2022
Brigita Banjac, Ivana Milovanović, Saša Pišot, Radenko Matić, Stevo Popović, Sandra Radenović, Patrik Drid, 2023, izvirni znanstveni članek

Povzetek: The COVID-19 pandemic profoundly changed everyday life of social actors, which inferred mental health and well-being concerns. As students of health-related studies tend to adapt better to difficult circumstances, in this study, we explored the effect of the pandemic on sports science students’ well-being during the summer of 2022. The research was conducted in Slovenia and Serbia. The sample comprised n = 350 students. The PERMA-Profiler, a 15-item self-reported questionnaire, was adapted to assess well-being across five elements: positive emotions, engagement, relationships, meaning, and accomplishment. Data were collected with a questionnaire through the summer of 2022 (from May to July) and analyzed in SPSS, AMOS 26.0. The results revealed normal functioning (M = 7.72, SD ± 1.38) for the overall well-being of the students. Although all dimensions indicated high scores, relationships (M = 7.95, SD ± 1.63), meaning (M = 7.76, SD ± 1.69), and engagement (M = 7.73, SD ± 1.36) rated the highest. Furthermore, the instrument was acceptable, as the confirmatory factor analysis showed adequate reliability based on Cronbach's alpha (15 items, α = 0.94) and strong internal correlations between the PERMA dimensions. This study contributes to the previously published research, emphasizing the positive responses and successful coping of sports science students in times of complex situations, such as the COVID-19 pandemic.
Ključne besede: sport, health science, physical education, university students, pandemics, mental health, well-being
Objavljeno v DiRROS: 16.02.2023; Ogledov: 368; Prenosov: 205
.pdf Celotno besedilo (547,15 KB)
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7.
CitieS-Health : Ljubliteljska znanost za zdravje v mestnem okolju
David Kocman, Uroš Kunaver, 2022, strokovni film, videoposnetek ali zvočni posnetek

Ključne besede: občanska znanost, projekt Horizon 2020, okoljska znanost, Projekt Cities-Health, zdravje na delovnem mestu
Objavljeno v DiRROS: 31.01.2023; Ogledov: 342; Prenosov: 150
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8.
Citizen science and monitoring forest pests : a beneficial alliance?
Maarten De Groot, Michael J.O. Pocock, Jochem Bonte, Pilar Fernandez-Conradi, Elena Valdés-Correcher, 2022, izvirni znanstveni članek

Povzetek: Purpose of the Review One of the major threats to tree health, and hence the resilience of forests and their provision of ecosystem services, is new and emerging pests. Therefore, forest health monitoring is of major importance to detect invasive, emerging and native pest outbreaks. This is usually done by foresters and forest health experts, but can also be complemented by citizen scientists. Here, we review the use of citizen science for detection and monitoring, as well as for hypothesis-driven research and evaluation of control measures as part of forest pest surveillance and research. We then examine its limitations and opportunities and make recommendations on the use of citizen science for forest pest monitoring. Recent Findings The main opportunities of citizen scientists for forest health are early warning, early detection of new pests, monitoring of impact of outbreaks and scientific research. Each domain has its own limitations, opportunities and recommendations to follow, as well as their own public engagement strategies. The development of new technologies provides many opportunities to involve citizen scientists in forest pest monitoring. To enhance the benefits of citizen scientists’ inclusion in monitoring, it is important that they are involved in the cocreation of activities. Summary Future monitoring and research may benefit from tailor-made citizen science projects to facilitate successful monitoring by citizen scientists and expand their practice to countries where the forest health sector is less developed. In this sense, citizen scientists can help understand and detect outbreaks of new pests and avoid problems in the future.
Ključne besede: forest health, community science, forest management, awareness raising, forest protection
Objavljeno v DiRROS: 28.11.2022; Ogledov: 451; Prenosov: 213
.pdf Celotno besedilo (1,36 MB)
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9.
Availability and costs of medicines for the treatment of tuberculosis in Europe
Gunar Günther, Lorenzo Guglielmetti, Claude Leu, Christoph Lange, Frank van Leth, 2022, pregledni znanstveni članek

Povzetek: Objectives. To evaluate the access to comprehensive diagnostics and novel anti-tuberculosis medicines in European countries. Methods. We investigated access to genotypic and phenotypic M. tuberculosis drug susceptibility testing, availability of anti-tuberculosis drugs and calculated cost of drugs and treatment regimens at major tuberculosis treatment centers in countries of the World Health Organization (WHO) European region where rates of drug-resistant tuberculosis are highest among all WHO regions. Results are stratified by middle-income and high-income countries. Results. Overall, 43 treatment centers in 43 countries participated in the study. For WHO Group A drugs, the frequency of countries with availability of phenotypic drug susceptibility testing was as follows: 30/40 (75%) for levofloxacin, 33/40 (82%) for moxifloxacin, 19/40 (48%) for bedaquiline and 29/40 (72%) for linezolid, respectively. Overall, 36/43 (84%) and 24/43 (56%) of countries had access to bedaquiline and delamanid, while only 6/43 (14%) had access to rifapentine. Treatment of patients with extensively drug-resistant tuberculosis with a regimen including a carbapenem was only available in 17/43 (40%) of the countries. Median cost of regimens for drug-susceptible tuberculosis, multidrug-resistant/rifampicin-resistant tuberculosis (shorter regimen, including bedaquiline for six months) and extensively drug-resistant tuberculosis (including bedaquiline, delamanid and a carbapenem) were € 44 (min-max € 15-152), € 764 (min-max € 542-15152) and € 8709 (min-max € 7965-11759) in middle-income countries (n=12), and € 280 (min-max-€78-1084), € 29765 (min-max 11116-40584), € 217591 (min-max € 82827-320146) in high-income countries (n=29). Conclusion. In countries of the WHO Europe Region there is a widespread lack of drug susceptibility testing capacity to new and re-purposed anti-tuberculosis drugs, lack of access to essential medications in several countries and high treatment cost for drug-resistant tuberculosis.
Ključne besede: tuberculosis - drug therapy, Mycobacterium tuberculosis - drug therapy, health care costs - drug therapy, Europe
Objavljeno v DiRROS: 31.08.2022; Ogledov: 666; Prenosov: 137
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10.
The differences of Slovenian and Italian daily practices experienced in the first wave of covid-19 pandemic
Saša Pišot, Boštjan Šimunič, Ambra Gentile, Antonino Bianco, Gianluca Lo Coco, Rado Pišot, Patrik Drid, Ivana Milovanović, 2022, izvirni znanstveni članek

Povzetek: Background: The COVID-19 pandemic situation with the lockdown of public life caused serious changes in people’s everyday practices. The study evaluates the diferences between Slovenia and Italy in health-related everyday practices induced by the restrictive measures during frst wave of the COVID-19 pandemic. Methods: The cross-sectional cohort study examined changes through an online survey conducted in nine European countries from April 15–28, 2020. The survey included questions from a simple activity inventory questionnaire (SIMPAQ), the European Health Interview Survey, and some other questions. To compare diference in changes between European countries we examined Italy with severe and its neighbour country Slovenia with low incidence and victims of COVID-19 epidemic. 956 valid responses from Italy (N=511; 50% males) and Slovenia (N=445; 26% males) were investigated. Results: During the survey, there was a 4.7-fold higher incidence and 12.1-fold more deaths (per 100,000) in Italy than in Slovenia. Barring periods and measures were similar, the latter more stringent in Italy. We found more changes in Italy than in Slovenia: physical inactivity increased (Italy:+65% vs. Slovenia:+21%; p<0.001), walking time decreased (Italy: -68% vs. Slovenia: -4.4%; p<0.001); physical work increased by 38% in Slovenia (p<0.001), and recreation time decreased by 37% in Italy (p<0.001). Italians reported a decrease in quality of general health, ftness level, psychological well-being, quality of life and care for own health (p<0.001); Slovenians showed a decline in psychological well-being and quality of life (p<0.001) but generally had a higher concern for their own health (p=0.005). In pooled participants, changes in eating habits (meal size and consumption of unhealthy food), age and physical inactivity were positively correlated with increases in body mass, while changes in general well-being and concern for health were negatively correlated. Conclusion: The study shows that the negative impact of COVID -19 measures is greater in Italy where the pandemic COVID -19 was more prevalent than in Slovenia with low prevalence. Additional consideration should be given to the negative impact of COVID-19 measures on some health-related lifestyle variables when implementing further measures to mitigate the COVID-19 pandemic.
Ključne besede: coronavirus pandemic, pandemic measures, home confinement, public health, physical activity, physical inactivity, dietary habits, eating habits, well-being
Objavljeno v DiRROS: 18.02.2022; Ogledov: 659; Prenosov: 497
.pdf Celotno besedilo (1,19 MB)
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