1. The effect of different surfactants and polyelectrolytes on nano-vesiculation of artificial and cellular membranesUrška Zagorc, Darja Božič, Vesna Arrigler, Žiga Medoš, Matej Hočevar, Anna Romolo, Veronika Kralj-Iglič, Ksenija Kogej, 2024, izvirni znanstveni članek Ključne besede: extracellular vesicles, liposomes, surfactants, polyelectrolytes, static light scattering, dinamic light scattering, microcalorimetry, drug delivery, cell-to-cell communication
Objavljeno v DiRROS: 24.12.2024; Ogledov: 338; Prenosov: 152
 Celotno besedilo (3,13 MB)
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2. Assessment of extracellular particles directly in diluted plasma and blood by interferometric light microscopy : a study of 613 human and 163 canine samplesBoštjan Korenjak, Armando Tratenšek, Matevž Arko, Anna Romolo, Matej Hočevar, Matic Kisovec, Maxence Berry, Apolonija Bedina Zavec, David Drobne, Tomaž Vovk, Aleš Iglič, Alenka Nemec Svete, Vladimira Erjavec, Veronika Kralj-Iglič, 2024, izvirni znanstveni članek Ključne besede: extracellular particles, extracellular vesicles, exosomes, membrane vesiculation, platelets, blood products, platelet-rich plasma, liquid biopsy, membrane enclosed, drug delivery
Objavljeno v DiRROS: 20.12.2024; Ogledov: 323; Prenosov: 170
Celotno besedilo (1,96 MB)
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3. Nanoparticles for hyperthermic therapy : synthesis strategies and applications in glioblastomaJyoti Verma, Sumit Lal, Cornelis J. F. van Noorden, 2014, pregledni znanstveni članek Povzetek: Glioblastoma multiforme (GBM) is the most common and most aggressive malignant primary brain tumor in humans. Current GBM treatment includes surgery, radiation therapy, and chemotherapy, sometimes supplemented with novel therapies. Despite recent advances, survival of GBM patients remains poor. Major challenges in GBM treatment are drug delivery across the blood–brain barrier, restriction of damage to healthy brain tissues, and limitation of resistance to therapies. This article reviews recent advances in the application of magnetic nanoparticles (MNPs), gold nanorods (GNRs), and carbon nanotubes (CNTs) for hyperthermia ablation of GBM. First, the article introduces GBM, its current treatment, and hyperthermia as a potential modality for the management of GBM. Second, it introduces MNPs, GNRs, and CNTs as inorganic agents to induce hyperthermia in GBM. Third, it discusses different methodologies for synthesis of each inorganic agent. Finally, it reviews in vitro and in vivo studies in which MNPs, GNRs, and CNTs have been applied for hyperthermia ablation and drug delivery in GBM.
Ključne besede: hyperthermia, targeted drug delivery, SPIONs, gold nanorods, carbon nanotubes
Objavljeno v DiRROS: 06.08.2024; Ogledov: 526; Prenosov: 322
Celotno besedilo (2,20 MB)
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4. A web-application that extends functionality of medical device for tumor treatment by means of electrochemotherapyIvan Pavlović, Peter Kramar, Selma Čorović, David Cukjati, Damijan Miklavčič, 2004, izvirni znanstveni članek Povzetek: Electrochemotherapy (ECT) is a novel method for efficient tumor treatment in clinical environment. It combines local drug delivery and application of shorthigh voltage pulses, which permeabilize the plasma membrane by electroporation. Drug can enter only the cells with permeabilzed membrane. Recently, medical device CliniporatorTM for controlled electroporation was developed. Here, we present a web-application that extends the functionality of this medical device. The aim of the application is to collect, store and toallow the analysis of every ECT application using this medical device. The application helps transferring data collected by devčce during the electroporation process to the central database, and enables filling of medical records through the web forms. The application is based on technologies ASP, HTML, Flash, JavaScript, XML and others. The application main advantages are easy and rapid data access, scalability and independence of client computer operating system as well as easy application debugging and upgrading.
Ključne besede: neoplasms- drug therapy, drug delivery systems, elektroporation instrumentation
Objavljeno v DiRROS: 07.02.2024; Ogledov: 921; Prenosov: 220
Celotno besedilo (133,39 KB) |
5. Small cellular particles from European spruce needle homogenateMarko Jeran, Anna Romolo, Vesna Spasovski, Matej Hočevar, Urban Novak, Roman Štukelj, Vid Šuštar, Matic Kisovec, Apolonija Bedina Zavec, Ksenija Kogej, Aleš Iglič, Polonca Trebše, Veronika Kralj-Iglič, 2023, izvirni znanstveni članek Ključne besede: Picea abies, spruce needles, extracellular particles, extracellular vesicles, small cellular particles, interferometric light microscopy, exosomes, cell-to-cell communication, drug delivery
Objavljeno v DiRROS: 07.02.2024; Ogledov: 805; Prenosov: 447
Celotno besedilo (2,49 MB)
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