1. Odkrivanje in z vodo povezana epidemiologija porajajočih se tobamovirusov, ki okužujejo kmetijske rastlineNataša Mehle, Denis Kutnjak, Ana Vučurović, Ion Gutiérrez-Aguirre, Katarina Bačnik, Luka Kranjc, Irena Bajde, Jakob Brodarič, Maja Ravnikar, Olivera Maksimović, Mark Paul Selda Rivarez, Tomaž Curk, Neža Pajek Arambašić, Rok Štravs, 2024, končno poročilo o rezultatih raziskav Ključne besede: diagnostika, rastlinski virusi, ToBRFV, ToMMV, tobamovirusi, epidemiologija, voda kot vir okužb, poročila
Objavljeno v DiRROS: 20.02.2025; Ogledov: 214; Prenosov: 50
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2. Program strokovnih nalog s področja zdravstvenega varstva rastlin : naloge zdravstvenega varstva rastlin po javnem pooblastiluNataša Mehle, Manca Pirc, Ana Vučurović, Marjana Camloh, Denis Kutnjak, Anja Pecman, Špela Alič, Aleksander Benčič, Vladimir Grujić, Neža Turnšek, Janja Matičič, Špela Prijatelj-Novak, Aleš Blatnik, Jakob Brodarič, Irena Bajde, Veronika Bukvič, Tjaša Jakomin, Tanja Dreo, 2025, končno poročilo o rezultatih raziskav Ključne besede: diagnostika, virusi, bakterije, fitoplazme, varstvo rastlin
Objavljeno v DiRROS: 03.02.2025; Ogledov: 278; Prenosov: 0
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4. Program strokovnih nalog s področja zdravstvenega varstva rastlin : končno poročilo za leto 2024 o opravljenem delu v okviru konzorcija nacionalnega referenčnega laboratorija za viruse, viroide in fitoplazmeNataša Mehle, Irena Mavrič Pleško, Janja Lamovšek, Sebastjan Radišek, Tanja Guček, Jakob Brodarič, Irena Bajde, Denis Kutnjak, Ana Vučurović, 2025, končno poročilo o rezultatih raziskav Ključne besede: diagnostika, virusi, viroidi, fitoplazme, varstvo rastlin
Objavljeno v DiRROS: 17.01.2025; Ogledov: 251; Prenosov: 2
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5. CA19-9 serum levels predict micrometastases in patients with gastric cancerTomaž Jagrič, Stojan Potrč, Katarina Miš, Mojca Plankl, Tomaž Marš, 2016, izvirni znanstveni članek Povzetek: Background. We explored the prognostic value of the up-regulated carbohydrate antigen (CA19-9) in node-negative patients with gastric cancer as a surrogate marker for micrometastases. Patients and methods. Micrometastases were determined using reverse transcription quantitative polymerase chain reaction (RT-qPCR) for a subgroup of 30 node-negative patients. This group was used to determine the cut-off for preoperative CA19-9 serum levels as a surrogate marker for micrometastases. Then 187 node-negative T1 to T4 patients were selected to validate the predictive value of this CA19-9 threshold. Results. Patients with micrometastases had significantly higher preoperative CA19-9 serum levels compared to patients without micrometastases (p = 0.046). CA19-9 serum levels were significantly correlated with tumour site, tumour diameter, and perineural invasion. Although not reaching significance, subgroup analysis showed better five-year survival rates for patients with CA19-9 serum levels below the threshold, compared to patients with CA19-9 serum levels above the cut-off. The cumulative survival for T2 to T4 node-negative patients was significantly better with CA19-9 serum levels below the cut-off (p = 0.04). Conclusions. Preoperative CA19-9 serum levels can be used to predict higher risk for haematogenous spread and micrometastases in node-negative patients. However, CA19-9 serum levels lack the necessary sensitivity and specificity to reliably predict micrometastases.
Ključne besede: gastric cancer, micrometastases, CA19-9, rak (medicina), želodec, metastaze, diagnostika, antigeni, tumorski označevalci
Objavljeno v DiRROS: 09.05.2024; Ogledov: 695; Prenosov: 391
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6. Non-contrast computed tomography in the diagnosis of cerebral venous sinus thrombosisJernej Avsenik, Janja Pretnar-Oblak, Katarina Šurlan Popović, 2016, izvirni znanstveni članek Povzetek: Due to the diversity of underlying factors and the absence of a uniform treatment approach, diagnosis and management of patients with cerebral venous sinus thrombosis (CVST) remain a challenging task.1 CVST represents 0.5% to 1% of all strokes and affects approximately 5 patients per million every year, but has a higher frequency among younger patients. Typical acquired risk factors include recent surgery, trauma, pregnancy, postpartum state, antiphospholipid syndrome, cancer and use of oral contraceptives. Cases of inherited thrombophilia include Antithrombin III, Protein C and Protein S deficiency, factor V Leiden positivity, prothrombin gene mutation and hyperhomocisteinemia. Infection of parameningeal spaces (ears, paranasal sinuses, oral cavity, face and neck) is common cause of CVST in pediatric population but rare in adults. The symptoms of CVST are not specific. The most common complaint is headache which occurs in up to 90% of patients. Additionally, abnormal vision, any of the symptoms of stroke and seizures have been described. In the past D-dimer levels appeared to be of value as an initial screening test. A study in 2004 evaluated the sensitivity of D-dimer to be 97.1% and specificity 99.1%.8 However, later studies showed that up to 10% of patients with CVST have a normal D-dimer. As it is fast, affordable and widely available, non-contrast computed tomography (NCCT) is the most frequently performed imaging study for evaluation of patients with new headache, focal neurological abnormalities, seizure, or change in mental status. A typical imaging finding in patients with CVST is direct visualization of a hyperattenuating thrombus in the occluded sinus (dense sinus sign). Occasionally, NCCT may only show indirect signs of thrombosis, including diffuse brain edema and parenchymal hemorrhage. Sensitivity of NCCT in the diagnosis of CVST was previously considered rather poor. However, using modern multidetector row CT scanners, recent studies report higher sensitivity and specificity values. In addition, Buyck et al. suggest measurement of the venous sinus attenuation to increase the diagnostic yield of the examination. Therefore, the goal of the present study was to evaluate the diagnostic accuracy of NCCT in the diagnosis of CVST in the emergency setting
Ključne besede: cerebral venous sinus thrombosis, computed tomography, stroke, radiologija, računalniška tomografija, diagnostika, možganski venski sinusi
Objavljeno v DiRROS: 09.05.2024; Ogledov: 576; Prenosov: 379
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7. Optimal scan time for evaluation of parathyroid adenoma with [18F]-fluorocholine PET/CTSebastijan Rep, Luka Ležaič, Tomaž Kocjan, Marija Pfeifer, Mojca Jensterle Sever, Urban Simončič, Petra Tomše, Marko Hočevar, 2015, izvirni znanstveni članek Ključne besede: lesions representing enlarged parathyroid tissue, triple-phase, standardized uptake value, retention index, lesion contrast, rak (medicina), obščitnični adenomi, diagnostika
Objavljeno v DiRROS: 22.04.2024; Ogledov: 866; Prenosov: 577
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10. Clonality analysis of lymphoid proliferations using BIOMED-2 clonality assays : a single institution experienceIra Kokovič, Barbara Jezeršek Novaković, Petra Škerl, Srdjan Novaković, 2014, strokovni članek Ključne besede: onkologija, rak (medicina), limfom, diagnostika, analiza, molekularne metode, molekularna diagnostika
Objavljeno v DiRROS: 10.04.2024; Ogledov: 655; Prenosov: 216
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