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Iskalni niz: "ključne besede" (cutaneous melanoma) .

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1.
Skin cancer segmentation and classification by implementing a hybrid FrCN-(U-NeT) technique with machine learning
Puneet Thapar, Manik Rakhra, Deepak Prashar, Leo Mršić, Arfat Ahmad Khan, Seifedine Kadry, 2025, izvirni znanstveni članek

Povzetek: Skin cancer is a severe and rapidly advancing condition that can be impacted by multiple factors, including alcohol and tobacco use, allergies, infections, physical activity, exposure to UV light, viral infections, and the effects of climate change. While the steep death tolls continue rising at an alarming rate, lack of symptoms recognition and its preventive measures further worsen the case. In this article, we employ the ISBI-2017 dataset to present an improved FrCN-based hybrid image segmentation method with U-Net to improve detection performance. This paper proposes a hybrid approach using the FrCN-(U-Net) image segmentation technique to enhance results compared to an advanced method for detecting skin cancer types, such as Benign or Melanoma. The classification phase is then handled using the R-CNN algorithm. Our model shows better performance in both training and testing accuracy than any other existing approaches. The results show that the combined method is effective in enhancing early disease diagnosis, which in turn improves treatment outcomes and prognosis. This paper presents an alternative technique for skin cancer detection, which can serve as a guide for clinical practices and public health strategies on how to lower skin-cancer-related deaths.
Ključne besede: skin tumors, cutaneous melanoma, lesions, imaging techniques, cancel detection and diagnosis, melanoma, preprocessing, melignant tumors
Objavljeno v DiRROS: 19.06.2025; Ogledov: 58; Prenosov: 23
.pdf Celotno besedilo (1,31 MB)
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2.
Completely resected stage III melanoma controversy : 15 years of national tertiary centre experience
Barbara Perić, Sara Milićević, Andraž Perhavec, Marko Hočevar, Janez Žgajnar, 2021, izvirni znanstveni članek

Povzetek: Background Two prospective randomized studies analysing cutaneous melanoma (CM) patients with sentinel lymph node (SLN) metastases and rapid development of systemic adjuvant therapy have changed our approach to stage III CM treatment. The aim of this study was to compare results of retrospective survival analysis of stage III CM patients% treatment from Slovenian national CM register to leading international clinical guidelines. Patients and methods Since 2000, all Slovenian CM patients with primary tumour % TIb are treated at the Institute of Oncology Ljubljana and data are prospectively collected into a national CM registry. A retrospective analysis of 2426 sentinel lymph node (SLN) biopsies and 789 lymphadenectomies performed until 2015 was conducted using Kaplan-Meier survival curves and log-rank tests. Results Positive SLN was found in 519/2426 (21.4%) of patients and completion dissection (CLND) was performed in 455 patients. The 5-year overall survival (OS) of CLND group was 58% vs. 47% of metachronous metastases group (MLNM) (p = 0.003). The 5-year OS of patients with lymph node (LN) metastases and unknown primary site (UPM) was 45% vs. 21% of patients with synchronous LN metastasis. Patients with SLN tumour burden < 0.3 mm had 5-year OS similar to SLN negative patients (86% vs. 85%; p = 0.926). The 5-year OS of patients with burden > 1.0 mm was similar to the MLNM group (49% vs. 47%; p = 0.280). Conclusions Stage III melanoma patients is a heterogeneous group with significant OS differences. CLND after positive SLNB might still remain a method of treatment for selected patients with stage III.
Ključne besede: cutaneous melanoma, surgery treatment, sentinel node biopsy
Objavljeno v DiRROS: 17.07.2024; Ogledov: 619; Prenosov: 319
.pdf Celotno besedilo (406,28 KB)
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