1. The role of extracellular vesicles in phenotypic cancer transformationEva Ogorevc, Veronika Kralj-Iglič, Peter Veranič, 2013, pregledni znanstveni članek Povzetek: Background. Cancer has traditionally been considered as a disease resulting from gene mutations. New findings in biology are challenging gene-centered explanations of cancer progression and redirecting them to the non-genetic origins of tumorigenicity. It has become clear that intercellular communication plays a crucial role in cancer progression. Among the most intriguing ways of intercellular communication is that via extracellular vesicles (EVs). EVs are membrane structures released from various types of cells. After separation from the mother membrane, EVs become mobile and may travel from the extracellular space to blood and other body fluids. Conclusions. Recently it has been shown that tumour cells are particularly prone to vesiculation and that tumour-derived EVs can carry proteins, lipids and nucleic acids causative of cancer progression. The uptake of tumour-derived EVs by noncancerous cells can change their normal phenotype to cancerous. The suppression of vesiculation could slow down tumour growth and the spread of metastases. The purpose of this review is to highlight examples of EV-mediated cancer phenotypic transformation in the light of possible therapeutic applications.
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2. Short term effect of plant hybridosomes on growth of phaeodactylum tricornutum cultureAnna Romolo, Matej Hočevar, Aleš Iglič, Tjaša Griessler Bulc, Veronika Kralj-Iglič, 2023, objavljeni znanstveni prispevek na konferenci Ključne besede: Phaeodactylum tricornutum, hybridosomes, liposomes, nanoalgosomes, extracellular vesicles, small cellular particles, microalgae
Objavljeno v DiRROS: 21.03.2024; Ogledov: 83; Prenosov: 42
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7. Scanning electron microscope images of isolates of small cellular particles Phaeodactylum tricornutum grown in media supplemented with Guillard’s (F/2) marine : marine water enrichment solution, BG11 broth and Lennox LB brothApolonija Bedina Zavec, Darja Božič, Matej Hočevar, Aleš Iglič, Marko Jeran, Veronika Kralj-Iglič, Anna Romolo, 2024, objavljeni znanstveni prispevek na konferenci Objavljeno v DiRROS: 08.03.2024; Ogledov: 84; Prenosov: 43
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10. Breast cancer and breast health awareness as an evolving health promotion conceptAndrej Plesničar, Viljem Kovač, Božo Kralj, 2004, izvirni znanstveni članek Povzetek: Background. Breast cancer is the most frequent malignant disease in the majority of developed countries. In the last few years the introduction of mammography screening programmes has resulted in an improved survival of breast cancer patients. However, the incidence of the disease in these countries is still on the increase. Present focus on secondary breast cancer prevention activities, consisting of early detection and treatment, cannot ensure a decrease of breast cancer incidence. Improved breast health awarenesscould therefore represent a part of specific health promotion activities aimed at decreasing the incidence of breast cancer. Conclusions. Indeveloped countries breast cancer is a significant health care issue. Secondary breast cancer prevention activities should therefore be complementedby specific health promotion activities in order to reduce its incidence in the future. Primary breast cancer prevention would include healthpromotion activities aimed at enhancement of the individual as well as collective breast health awareness. Properly enlightened members of the influential population groups could attain appropriate changes in the fields of legislation, taxation, customs and commercial regulations that would enablewomen to control their own breast health.
Objavljeno v DiRROS: 07.02.2024; Ogledov: 166; Prenosov: 35
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