1. Osteoblastic bone metastases from renal cell carcinomaVladka Salapura, Irena Preložnik Zupan, Boštjan Šeruga, Gorana Gašljević, Pavel Kavčič, 2014, izvirni znanstveni članek Povzetek: Background. RCC accounts for only 2-3% of all cancers. Due to its non-specific symptoms disease is often diagnosed in advanced stage. Disseminated RCC frequently produces bone metastases that are almost always highly destructive, hyper vascularized and purely osteolytic. Case report. In this article we describe a case of a 71-year old male patient with disseminated osteoblastic bone metastases from renal cell carcinoma (RCC), and present a short review of published literature reporting cases of osteoblastic bone metastases from RCC. Our patient presented with thoracic pain aggravated by movement. He was diagnosed with predominantly osteoblastic bone metastases in the skeleton of thoracic and lumbar vertebra along with metastases in iliac bones, ribs, humerus and clavicles. Initially, origin of bone metastases was unknown, but later a small tumor in patients right kidney was identified. Microscopic evaluation of the open bone biopsy showed clear cell RCC with sarcomatoid differentiation. Conclusions. Although, due to its rarity, RCC is not included in the primary differential diagnosis in patients with osteoblastic metastases, such rare cases suggest that RCC may be considered in the diagnosis when there no other primary tumor is found.
Objavljeno v DiRROS: 11.04.2024; Ogledov: 66; Prenosov: 8
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2. An experimental study of liquid micro-jets produced with a gas dynamic virtual nozzle under the influence of an electric fieldBor Zupan, Gisel Esperanza Peña-Murillo, Rizwan Zahoor, Jurij Gregorc, Božidar Šarler, Juraj Knoška, Alfonso M. Gañán-Calvo, Henry N. Chapman, Saša Bajt, 2023, izvirni znanstveni članek Povzetek: The results of an experimental study of micro-jets produced with a gas dynamic virtual nozzle (GDVN) under the influence of an electric field are provided and discussed for the first time. The experimental study is performed with a 50% volume mixture of water and ethanol, and nitrogen focusing gas. The liquid sample and gas Reynolds numbers range from 0.09–5.4 and 0–190, respectively. The external electrode was positioned 400–500 μm downstream of the nozzle tip and an effect of electric potential between the electrode and the sample liquid from 0–7 kV was investigated. The jetting parametric space is examined as a function of operating gas and liquid flow rates, outlet chamber pressure, and an external electric field. The experimentally observed jet diameter, length and velocity ranged from 1–25 μm, 50–500 μm and 0.5–10 m/s, respectively. The jetting shape snapshots were processed automatically using purposely developed computer vision software. The velocity of the jet was calculated from the measured jet diameter and the sample flow rate. It is found that micro-jets accelerate in the direction of the applied electric field in the downstream direction at a constant acceleration as opposed to the standard GDVNs. New jetting modes were observed, where either the focusing gas or the electric forces dominate, encouraging further theoretical and numerical studies towards optimized system design. The study shows the potential to unlock a new generation of low background sample delivery for serial diffraction measurements of weakly scattering objects.
Ključne besede: micro jet, electric field, experimental study, flow focusing, Taylor cone, gas dynamic virtual nozzles
Objavljeno v DiRROS: 07.02.2024; Ogledov: 180; Prenosov: 75
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3. Modificirajući uticaj na neke endokrine žlezde miša kod kasnih posledica subletalnog jonizacionog zračenjaMiroslav Kališnik, Olga Vraspir-Porenta, Metka Logonder-Mlinšek, Marjeta Zorc, Tatjana Lejko-Zupanc, Alenka Rus-Gaši, Draga Štiblar-Martinčič, Janez Škrk, 1979, izvirni znanstveni članek Objavljeno v DiRROS: 14.09.2023; Ogledov: 246; Prenosov: 57
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