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3. Rak jajčnikov : zanositev in nosečnost2024, zbornik recenziranih znanstvenih prispevkov na domači konferenci Povzetek: Predstavljamo vam zbornik znanstvenih prispevkov, ki naslavlja kompleksen odnos med rakom jajčnikov, zanositvijo in nosečnostjo. Gre za tematiko, ki v medicinskih in raziskovalnih krogih postaja vse bolj aktualna, saj tehnološki in terapevtski napredek omogočata razvoj novih pristopov, ki izboljšujejo kakovost življenja bolnic in odpirajo možnosti za ohranjanje plodnosti tudi pri onkoloških bolnicah.
Objavljeno v DiRROS: 24.01.2025; Ogledov: 509; Prenosov: 312
 Celotno besedilo (1,43 MB)
Gradivo ima več datotek! Več... |
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8. Sodobna dognanja : 8. šola o ginekološkem raku2024, ni določena Povzetek: Raki rodil predstavljajo pomemben zdravstveni izziv za ženske po vsem svetu. So raznovrstna skupina bolezni katere preživetje se močno razlikuje glede na prizadetost organa, razširjenost
bolezni, odgovora na zdravljenje in psihofizičnega stanja bolnice.
V zadnjih letih smo priča izjemnim napredkom na področju medicinske obravnave in zdravstvenih raziskav, ki so privedla do bistvenih izboljšav pri obravnavi bolnic z ginekološkim rakom. Sodobne metode zdravljenja ne le povečujejo možnosti za preživetje, temveč bistveno prispevajo k višji kakovosti življenja onkoloških bolnic. Z vlaganjem v raziskave in izobraževanje lahko dosežemo nove preboje, ki bodo koristili prihodnjim generacijam žensk.
Ključne besede: ginekologija, onkologija, ginekološka onkologija, zdravljenje, ginekološka kirurgija, radioterapija, imunoterapija, laserska terapija, plodnost, parenteralna prehrana, zborniki, elektronske knjige
Objavljeno v DiRROS: 05.09.2024; Ogledov: 974; Prenosov: 487
Celotno besedilo (1,37 MB)
Gradivo ima več datotek! Več... |
9. Modern approach to the management of genitourinary syndrome in women with gynecological malignanciesNina Kovačević, Ines Cilenšek, Sebastjan Merlo, Barbara Šegedin, 2023, pregledni znanstveni članek Povzetek: The term genitourinary syndrome of menopause was first used in 2014 by the North American Menopause Society and the International Society for the Study of Women's Sexual Health to describe conditions previously known as atrophic vaginitis, urogenital atrophy, or vulvovaginal atrophy. It is a complex, chronic, progressive condition characterized by a wide range of signs and symptoms affecting sexual function and the tissues of the urinary and genital tracts. The main cause of genitourinary syndrome of menopause is estrogen deficiency caused by ovarian removal or dysfunction. The most bothersome symptoms are vaginal dryness, decreased vaginal lubrication, and pain during penetration and intercourse. They all have a negative impact on the quality of life. Conclusions: The main goal of treatment is to relieve the symptoms. Treatment modalities are pharmacological or non-pharmacological. The first-line treatment for mild to moderate symptoms is the use of personal lubricants and moisturizers, but the gold standard is estrogen replacement therapy. Hormone therapy may not be an option for women with hormone-dependent cancer.
Ključne besede: genitourinary syndrome, gynecological malignancies, therapy
Objavljeno v DiRROS: 25.07.2024; Ogledov: 839; Prenosov: 377
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10. Treatment of vulvar cancer recurrences with electrochemotherapy : a detailed analysis of possible causes for unsuccessful treatmentGregor Vivod, Tanja Jesenko, Gorana Gašljević, Nina Kovačević, Maša Omerzel, Gregor Serša, Sebastjan Merlo, Maja Čemažar, 2023, izvirni znanstveni članek Povzetek: Background. Electrochemotherapy has good local effectiveness in the treatment of vulvar cancer. Most studies have reported the safety and effectiveness of electrochemotherapy for palliative treatment of gynecological cancers and mostly vulvar squamous cell carcinoma. Some tumors, however, fail to respond to electrochemotherapy. The biological features/determinants for the nonresponsiveness are not determined yet. Patient and methods. A recurrence of vulvar squamous cell carcinoma was treated by electrochemotherapy using intravenous administration of bleomycin. The treatment was performed by hexagonal electrodes according to standard operating procedures. We analyzed the factors that could determine nonresponsiveness to electrochemotherapy. Results. Based on the presented case of nonresponsive vulvar recurrence to electrochemotherapy, we hypothesize that the vasculature of the tumors prior to treatment may predict the response to electrochemotherapy. The histological analysis showed minimal presence of blood vessels in the tumor. Thus, low perfusion may reduce drug delivery and lead to a lower response rate because of the minor antitumor effectiveness of vascular disruption. In this case, no immune response in the tumor was elicited by electrochemotherapy. Conclusions. In this case, of nonresponsive vulvar recurrence treated by electrochemotherapy, we analyzed possible factors that could predict treatment failure. Based on histological analysis, low vascularization of the tumor was observed, which hampered drug delivery and distribution and resulted in no vascular disrupting action of electrochemotherapy. All these factors could contribute to ineffective treatment with electrochemotherapy.
Ključne besede: electrochemotherapy, bleomycin, vulvar cancer
Objavljeno v DiRROS: 25.07.2024; Ogledov: 927; Prenosov: 399
Celotno besedilo (1,49 MB) |
