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Iskalni niz: "avtor" (Monika %C4%8Ce%C5%A1njevar) .

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Mechanisms of premature fracture in modular neck stems made of CoCrMo/Ti6Al4V and Ti6Al4V/Ti6Al4V alloy
Drago Dolinar, Miro Gorenšek, Klemen Avsec, Barbara Šetina, Matej Hočevar, Matjaž Godec, Borut Žužek, Mojca Debeljak, Monika Jenko, John T. Grant, Boštjan Kocjančič, 2023, izvirni znanstveni članek

Povzetek: In this paper, we present the mechanisms of premature fracture of modular neck stems in two case studies: (I) when the neck and stem are both made of the same Ti6Al4V alloy, and (II) when the neck and stem are made from two different alloys, CoCrMo and Ti6Al4V alloy. Our study integrates two orthopedic patients who have undergone primary uncemented THA for usual indications in two orthopedic centers (Community Health Centre and University Medical Centre). Both centers are part of the national public health care system. Both surgeries were performed by two skilled orthopedic surgeons with more than 10 years of experience in THA. The survivorship of the modular neck of cast CoCrMo alloy was 24 months. The survivorship of the modular neck from Ti6Al4V alloy was 84 months. Multivariate analyses were performed to assess the differences in the fretting, corrosion, and fatigue of the two prematurely failed modular neck stems: stereo light microscopy (SLM), scanning electron microscopy (SEM), X-ray energy-dispersive spectroscopy (EDS), and electron backscatter diffraction (EBSD). Patient demographic information, including sex, age, body mass index, survivorship of implants, and reason for the revision, was collected from medical records. We found that fretting and fatigue occurred on both neck-stem retrievals due to additional galvanic corrosion, but the CoCrMo/Ti6Al4V alloy system suffered more corrosion due to additional galvanic corrosion and fractured earlier than the Ti6Al4V/Ti6Al4V metal alloy system. Both metallic alloy systems used in this application are known to be highly corrosion-resistant, but the bio-tribo-corrosion processes need to be understood in detail and characterized so that appropriate improvements in design and materials can be made.
Ključne besede: total hip arthroplasty, modular neck, Ti6Al4V alloy, CoCrMo alloy, corrosion
Objavljeno v DiRROS: 07.02.2024; Ogledov: 174; Prenosov: 87
.pdf Celotno besedilo (5,12 MB)
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Extending BIM for air quality monitoring
Michael Nicolas Mrissa, Jan Vcelak, László Hajdu, Balázs Dávid, Miklós Ferenz Krész, Jakub Michal Sandak, Anna Malgorzata Sandak, Rok Kanduti, Monika Varkonji, Anja Jutraž, Katja Malovrh Rebec, 2020, objavljeni znanstveni prispevek na konferenci

Povzetek: As we spend more than 90% of our time inside buildings, indoor environmental quality is a major concern for healthy living. Recent studies show that almost 80% of people in European countries and the United States suffer from SBS (Sick Building Syndrome), which affects physical health, productivity and psychological well-being. In this context, environmental quality monitoring provides stakeholders with crucial information about indoor living conditions, thus facilitating building management along its lifecycle, from design, construction and commissioning to usage, maintenance and end-of-life. However, currently available modelling tools for building management remain limited to static models and lack integration capacities to efficiently exploit environmental quality monitoring data. In order to overcome these limitations, we designed and implemented a generic software architecture that relies on accessible Building Information Model (BIM) attributes to add a dynamic layer that integrates environmental quality data coming from deployed sensors. Merging sensor data with BIM allows creation of a digital twin for the monitored building where live information about environmental quality enables evaluation through numerical simulation. Our solution allows accessing and displaying live sensor data, thus providing advanced functionality to the end-user and other systems in the building. In order to preserve genericity and separation of concerns, our solution stores sensor data in a separate database available through an application programming interface (API), which decouples BIM models from sensor data. Our proof-of-concept experiments were conducted with a cultural heritage building located in Bled, Slovenia. We demonstrated that it is possible to display live information regarding environmental quality (temperature, relative humidity, CO2, particle matter, light) using Revit as an example, thus enabling end-users to follow the conditions of their living environment and take appropriate measures to improve its quality
Ključne besede: Building Information Model, internet of things, environmental quality monitoring, healthy living
Objavljeno v DiRROS: 19.01.2024; Ogledov: 152; Prenosov: 70
.pdf Celotno besedilo (18,89 MB)
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Priprava in aplikacija sistemske terapije
Monika Sonc, Alenka Kovačič, 2023, objavljeni znanstveni prispevek na konferenci

Ključne besede: onkološka zdravila, sistemska terapija, zdravstvena nega
Objavljeno v DiRROS: 22.11.2023; Ogledov: 202; Prenosov: 80
.pdf Celotno besedilo (260,22 KB)

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Tribocorrosive study of new and in vivo exposed nickel titanium and stainless steel orthodontic archwires
Tadeja Kosec, Petra Močnik, Uroš Mezeg, Andraž Legat, Maja Ovsenik, Monika Jenko, John T. Grant, Jasmina Primožič, 2020, izvirni znanstveni članek

Povzetek: The surface, corrosion and wear properties of new and in vivo exposed nickel titanium (NiTi) and stainless steel (SS) archwires used in orthodontic treatment were investigated. Electrochemical and tribo-electrochemical tests in artificial saliva were performed in order to define corrosion properties and to estimate wear rate of new and in vivo exposed NiTi and SS archwires. The surface chemical analysis of the passive film on the NiTi and SS archwires before and after tribocorrosion tests was performed by Auger Electron Spectroscopy (AES). In vivo exposed NiTi and SS archwires had better electrochemical properties than new archwires due to the protective nature of oral deposits. Total wear and coefficients of friction were higher among in vivo exposed archwires and higher in NiTi archwires in comparison to SS archwires. The estimated thickness of the TiO2 passive film on as-received NiTi is 8 nm, while the passive Cr2O3 film on as-received SS is just 1–2 nm. On in vivo exposed NiTi archwire, a 60–80 nm thick organic film/dental plaque was observed, and on SS, it was thinner, at about 60 nm. This research shows the importance of combining AES with electrochemical testing, to characterize tribocorrosive properties of NiTi and SS orthodontic archwires.
Ključne besede: archwires, NiTi, stainless steel, wear
Objavljeno v DiRROS: 24.08.2023; Ogledov: 244; Prenosov: 100
.pdf Celotno besedilo (2,18 MB)
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Radiosenzibilizacija tumorjev z elektroprenosom plazmida za dve antiangiogeni tarči
Monika Savarin, Katarina Žnidar, Gregor Serša, Tilen Komel, Maja Čemažar, Urška Kamenšek, 2023, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: miši, elektroprenos genov, gensko zdravljenje
Objavljeno v DiRROS: 19.06.2023; Ogledov: 307; Prenosov: 119
.pdf Celotno besedilo (310,08 KB)
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Hormonsko nadomestno zdravljenje po zdravljenju raka telesa maternice
Monika Colja, 2023, objavljeni znanstveni prispevek na konferenci

Povzetek: Napredek zdravljenja na področju ginekološke onkologije je privedel do izboljšanja preživetja bolnic, ki živijo dovolj dolgo, da dočakajo naravno menopavzo ali inducirano menopavzo kot stranski učinek onkološkega zdravljenja. Pomisleki glede varnosti nadomestnega hormonskega zdravljenja po raku materničnega telesa vključujejo možnosti napredovanja ali ponovitve bolezni. Razpoložljivi podatki posameznih študij ne kažejo pomembnega tveganja za ponovitev bolezni, če se nadomestno hormonsko zdravljenje uporablja po zdravljenju zgodnjega stadija bolezni - stadij I ali II. Rak materničnega telesa je v večini primerov hormonsko odvisna bolezen, zato se kljub temu hormonska nadomestna terapija načeloma odsvetuje. Priporočajo se nehormonske alternative lajšanja menopavznih težav. Odločitev o zdravljenju s hormonsko nadomestno terapijo pri bolnicah po zdravljenju raka telesa maternice je kljub vsemu individualna in možna izjemoma za bolnice z zgodnjim stadijem bolezni po skrbnem premisleku glede koristi upoštevajoč možna tveganja. V nadaljevanju je predstavljen pregled literature na področju hormonskega nadomestnega zdravljenja po zdravljenju raka materničnega telesa.
Ključne besede: rak maternice, ginekološki raki, ginekološka onkologija
Objavljeno v DiRROS: 01.06.2023; Ogledov: 265; Prenosov: 122
.pdf Celotno besedilo (286,19 KB)
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