1. Vloga slovenskih odvetnikov in razvoj položaja slovenskega jezika kot pravnega jezika od 1848 do 1918Marko Novak, 2021, izvirni znanstveni članek Povzetek: Pomlad narodov leta 1848 je zahtevala enakopravnost ne le posameznikov, temveč tudi narodov. Rodila se je zahteva po enakopravnosti slovenskega jezika v tedanji monarhiji. V povezavi s tem so slovenski pravniki, kjer so prednjačili slovenski odvetniki, pričeli sistematično razvijati slovensko pravno terminologijo. To je bil eden izmed odločilnih korakov na poti do narodove pravne avtonomije, pomemben prispevek pa je sledil v začetku 20. stoletja z razpravljanjem o sposobnosti slovenskega naroda za lastno pravotvornost.
Ključne besede: pomlad narodov, jezikovno pravo, slovenski odvetniki, pravno-slavistična smer
Objavljeno v DiRROS: 03.09.2026; Ogledov: 138; Prenosov: 70
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2. Sarkomi mehkih tkiv : priporočilaMarko Novak, Nina Turnšek, Mojca Unk, Tina Žagar, Olga Blatnik, Sonja Kramer, Marija Skoblar Vidmar, Andraž Perhavec, Gregor Vivod, Ana Blatnik, Katja Kogovšek, Tilen Novosel, Saša Marušič, Lorna Zadravec-Zaletel, Andreja Klevišar Ivančič, Jerca Blazina, Snežana Đokić, Maja Ebert Moltara, Tjaša Maslo, Maja Česen, Jože Pižem, 2026, strokovni članek Povzetek: Priporočila za obravnavo in zdravljenje bolnikov s sarkomi mehkih tkiv poudarjajo pomen individualne obravnave bolnikov v referenčnem centru z multidisciplinarnim timom za sarkome. V Sloveniji je to Onkološki inštitut Ljubljana (OIL). Ključna je slikovna diagnostika z MR in CT preiskavo ter biopsija z debelo iglo. Kirurško zdravljenje je temelj zdravljenja, radioterapija pa zmanjša tveganje za lokalno ponovitev bolezni. Sistemsko zdravljenje s kemoterapijo ali tarčnimi zdravili prihaja v poštev predvsem pri razširjeni, metastatski bolezni. Priporočila 2026 so na voljo na spletni strani OIL.
Ključne besede: sarkomi, onkološko zdravljenje, referenčni centri, diagnostika
Objavljeno v DiRROS: 30.07.2026; Ogledov: 285; Prenosov: 100
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3. Influence of nutritional status and body composition on postoperative events and outcome in patients treated for primary localized retroperitoneal sarcomaManuel Ramanović, Marko Novak, Andraž Perhavec, Taja Jordan, Karteek Popuri, Nada Rotovnik-Kozjek, 2024, izvirni znanstveni članek Povzetek: Background: Retroperitoneal sarcomas (RPS) are rare tumours of mesenchymal origin, commonly presented as a large tumour mass at time of diagnosis. We investigated the impact of body composition on outcome in patients operated on for primary localized RPS. Patients and methods: We retrospectively analysed data for all patients operated on for primary RPS at our institution between 1999 and 2020. Preoperative skeletal muscle area (SMA), visceral and subcutaneous adipose tissue area (VAT and SAT) and muscle radiation attenuation (MRA) were calculated using computed tomography scans at the level of third lumbar vertebra. European Working Group on Sarcopenia in Older People (EWGSOP2) criteria were applied to define myopenia. Using maximum log-rank statistic method we determined the optimal cut-off values of body composition parameters. Myosteatosis was defined based on determined MRA cut-offs. Results: In total 58 patient were eligible for the study. With a median follow-up of 116 months, the estimated 5-year overall survival (OS) and local-recurrence free survival (LRFS) were 66.8% and 77.6%, respectively. Patients with myopenia had significantly lower 5-year OS compared to non-myopenic (p = 0.009). Skeletal muscle index and subcutaneous adipose tissue index predicted LRFS on univariate analysis (p = 0.052 and p = 0.039, respectively). In multivariate analysis high visceral-to-subcutaneous adipose tissue area ratio (VSR) independently predicted higher postoperative complication rate (89.2% vs. 10.8%, p = 0.008). Myosteatosis was associated with higher postoperative morbidity. Conclusions: Myopenia affected survival, but not postoperative outcome in RPS. Visceral obesity, VSR (> 0.26) and myosteatosis were associated with higher postoperative morbidity. VSR was better prognostic factor than VAT in RPS.
Ključne besede: body composition, cancer cachexia, obesity
Objavljeno v DiRROS: 26.06.2026; Ogledov: 273; Prenosov: 191
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4. Leiomyosarcoma of the renal vein : analysis of outcome and prognostic factors in the world case series of 67 patientsMarko Novak, Andraž Perhavec, Katherine E. Maturen, Snežana Đokić, Simona Jereb, Darja Eržen, 2017, izvirni znanstveni članek Povzetek: Background Leiomyosarcoma is a rare malignant mesenchymal tumour. Some cases of leiomyosarcoma of the renal vein (LRV) have been reported in the literature, but no analysis of data and search for prognostic factors have been done so far. The aim of this review was to describe the LRV, to analyse overall survival (OS), local recurrence free survival (LRFS) and distant metastases free survival (DMFS) in LRV world case series and to identify significant predictors of OS, LRFS and DMFS. Methods Cases from the literature based on PubMed search and a case from our institution were included. Results Sixty-seven patients with a mean age of 56.6 years were identified; 76.1% were women. Mean tumour size was 8.9 cm; in 68.7% located on the left side. Tumour thrombus extended into the inferior vena cava lumen in 13.4%. All patients but one underwent surgery (98.5%). After a median follow up of 24 months, the OS was 79.5%. LRFS was 83.5% after a median follow up of 21.5 months and DMFS was 76.1% after a median follow up of 22 months. Factors predictive of OS in univariate analysis were surgical margins, while factors predictive of LRFS were inferior vena cava luminal extension and grade. No factors predictive of DMFS were identified. In multivariate analysis none of the factors were predictive of OS, LRFS and DMFS. Conclusions Based on the literature review and presented case some conclusions can be made. LRV is usually located in the hilum of the kidney. It should be considered in differential diagnosis of renal and retroperitoneal masses, particularly in women over the age 40, on the left side and in the absence of haematuria. Core needle biopsy should be performed. Patients should be managed by sarcoma multidisciplinary team. LRV should be surgically removed, with negative margins.
Ključne besede: leiomysarcoma, renal vein, surgery, outcomes, prognostic factors
Objavljeno v DiRROS: 24.05.2024; Ogledov: 1745; Prenosov: 1036
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8. Izzivi sodobnih pristopov onkološke zdravstvene nege in zdravljenja : zbornik predavanj2010, zbornik strokovnih ali nerecenziranih znanstvenih prispevkov na konferenci Ključne besede: onkologija, kronične rane, zdravstvena nega, celjenje, bolečina, zdravstvena vzgoja, paliativna oskrba, posvetovanja, zborniki
Objavljeno v DiRROS: 04.06.2020; Ogledov: 4407; Prenosov: 1098
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