1. Innovative solutions for valorization of desalination brineAna Rotter, Baruch Rinkevich, Irem Deniz, Maggie M. Reddy, Mariana Girão, Maria F. Carvalho, Nina Gunde-Cimerman, Cene Gostinčar, Mercedes Cueto, Ernesta Grigalionyte-Bembič, 2025, izvirni znanstveni članek Povzetek: Desalination is becoming increasingly important to meet the growing demand for freshwater. However, a major drawback of this technology is the production of hypersaline brine. This by-product contains salts and contaminants that have been removed during the desalination process, including antiscalants, cleaning agents, heavy metals, and organic compounds. Instead of disposing of this brine and causing environmental harm, new strategies should be developed to transform brine from a burden into an opportunity with environmental and economic benefits. Brine can harbor halotolerant and halophilic microorganisms, making it a valuable resource for studying microbial diversity, adaptations and exploring untapped biotechnological opportunities in pharmaceutical, industrial, and ecological fields. We propose two strategies of innovation: (i) using brine to cultivate micro- and macro-organisms, both of which can create circular economy models tailored to global and local needs. (ii) In addition, the amount of brine generated by desalination plants can be reduced by integrating or coupling them with biodesalination modules. These modules would harness halotolerant and halophilic organisms to retain and assimilate salts, reducing the environmental impact of desalination. Ključne besede: desalination, brine, environmental impact, circular economy, biotechnology Objavljeno v DiRROS: 08.09.2025; Ogledov: 630; Prenosov: 325
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2. Maristem - stem cells of marine/aquatic invertebrates : from basic research to innovative applicationsLoriano Ballarin, Baruch Rinkevich, Kestin Bartscherer, Artur Burzynski, Sebastien Cambier, Matteo Cammarata, Isabelle Domart-Coulon, Damjana Drobne, Juanma Encinas, Uri Frank, Anne-Marie Geneviere, Bert Hobmayer, Helike Löhelaid, Daniel Lyons, Pedro Martinez, Paola Oliveri, Lorena Perić, Stefano Piraino, Andreja Ramšak, Sebastian Rakers, Fabian Rentzsch, Amalia Rosner, Tiago Henriques da Silva, Ildiko Somorjai, Sherif Suleiman, Ana Varela Coelho, 2018, izvirni znanstveni članek Povzetek: The “stem cells” discipline represents one of the most dynamic areas in biomedicine. While adult marine/aquatic invertebrate stem cell (MISC) biology is of prime research and medical interest, studies on stem cells from organisms outside the classical vertebrate (e.g., human, mouse, and zebrafish) and invertebrate (e.g., Drosophila, Caenorhabditis) models have not been pursued vigorously. Marine/aquatic invertebrates constitute the largest biodiversity and the widest phylogenetic radiation on Earth, from morphologically simple organisms (e.g., sponges, cnidarians), to the more complex mollusks, crustaceans, echinoderms, and protochordates. These organisms contain a kaleidoscope of MISC-types that allow the production of a large number of novel bioactive-molecules, many of which are of significant potential interest for human health. MISCs further participate in aging and regeneration phenomena, including whole-body regeneration. For years, the European MISC-community has been highly fragmented and has established scarce ties with biomedical industries in an attempt to harness MISCs for human welfare. Thus, it is important to (i) consolidate the European community of researchers working on MISCs; (ii) promote and coordinate European research on MISC biology; (iii) stimulate young researchers to embark on research in MISC-biology; (iv) develop, validate, and share novel MISC tools and methodologies; (v) establish the MISC discipline as a forefront interest of biomedical disciplines, including nanobiomedicine; and (vi) establish collaborations with industries to exploit MISCs as sources of bioactive molecules. In order to fill the recognized gaps, the EC-COST Action 16203 “MARISTEM” has recently been launched. At its initial stage, the consortium unites 26 scientists from EC countries, Cooperating countries, and Near Neighbor Countries. Ključne besede: aging, bioactive molecules, blue biotechnology, cancer, cell culture, COST Action, Europe, marine/aquatic invertebrates, regeneration, stem cells Objavljeno v DiRROS: 24.07.2024; Ogledov: 1579; Prenosov: 867
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