1. Structural and degradation studies of a biocompatible Zn-L-tartrate metal-organic frameworkJosip Bronić, Nataša Zabukovec Logar, Emanuela Žunkovič, Matjaž Mazaj, Andreas Puškarić, Ana Palčić, 2015 Povzetek: New anhydrous Zn-l-tratrate was synthesized under hydrothermal conditions. Crystal structure which was solved by powder X-ray diffraction data from monoclinic unit cell (I2, a=11.7557(1), b=9.0319(1), c=5.0750(1), β=91.920(1)) consists of the three-dimensional framework where each Zn atom coordinates four tartrate ligands in distorted octahedral geometry. Due to its biocompatible components, the degradation of material was studied in aqueous media under different pH values (pH=1–7) and in the simulated body fluid (pH=7.4) performed by the measurement of the released Zn2+ concentrations at thermostatic conditions (37 °C). The results showed that under acidic conditions approximately 60% of Zn2+ is released from the investigated material after 6 h of degradation process. With the increase of the solution’s pH, the rate of degradation gradually decreases. XRD and SEM analyses indicate that in aqueous media the compound slowly disintegrates and does not undergo hydrolysis process regardless of pH. Biocompatibility of the compound and its controllable rate of degradation even in acid conditions open its potential use in the fields of bio-applications.
Graphical abstract
The degradation kinetics of Zn-l-tar MOF material in aqueous media at different pH conditions.
Full-size image (24 K)
Ključne besede: Zn-tartrate, coordination polymers, hydrothermal synthesis, biomedical application, food supplement
DiRROS - Objavljeno: 26.01.2015; Ogledov: 4394; Prenosov: 315 |
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4. Standardization of PCM characterization via DSCStefan Gschwander, Thomas Haussmann, Georg Hagelstein, Aran Sole, Luisa F. Cabeza, Gonzalo Diarce, Wolfgang Hohenauer, Daniel Lager, Alenka Ristić, Christoph Rathgeber, Peter Hennemann, Harald Mehling, Conchita Peñalosa, Ana Lazaro, 2015 DiRROS - Objavljeno: 02.12.2015; Ogledov: 2440; Prenosov: 0 |
5. A polar/ [pi] model of interactions explains face-to-face stacked quinoid rings : a case study of the crystal of potassium hydrogen chloranilate dihydrateBartosz Zarychta, Ana Šantić, Emmanuel Wenger, Christian Jelsch, Slimane Dahaoui, Claude Lecomte, Biserka Kojić-Prodić, Jernej Stare, Krešimir Molčanov, 2015 DiRROS - Objavljeno: 22.03.2016; Ogledov: 3290; Prenosov: 460
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6. The impact of scald development on phenylpropanoid metabolism based on phenol content, enzyme activity, and gene expression analysisHeidrun Halbwirth, Anka Čebulj, Ana Slatnar, Robert Veberič, Maja Mikulič Petkovšek, 2020 Ključne besede: scald, gene expression, hydroxycinnamic acids, color, enzyme activity, phenol content, scald development, apples, cold storage
DiRROS - Objavljeno: 03.09.2020; Ogledov: 1112; Prenosov: 149
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8. Citološki izvid - klasifikacija po BethesdiAna Pogačnik, 2011 Povzetek: Glavni namen snovalcev klasifikacije po Bethesdi je bil ustvariti tako terminologijo sprememb na materničnem vratu, da bi bil citološki izvid Pap testa jasen in bi jasno odražal nadaljnjo obravnavo žensk. V Sloveniji smo leta 2006 spremenili klasifikacijo in se zelo približali Bethesdini, sedaj pa smo se odločili, da jo v celoti prevzamemo. Glavne spremembe so naslednje: v novem izvidu je bris uporaben ali neuporaben. Negativni bris delimo na normalen bris in neneoplastične spremembe, ki poleg reaktivnih sprememb iz stare klasifikacije vsebujejo še tubarno metaplazijo, žlezne celice po histerektomiji, endometrijske celice po 40. letu starosti in folikularni cervicitis. Med patološkimi spremembami je na ploščatem epiteliju najpomembnejša razlika ta, da je namesto atipičnih metaplastičnih celic dodana zelo pomembna kategorija atipičnih ploščatih celic, ne moremo pa izključiti ploščatocelične lezije visoke stopnje. Patološke spremembe žleznih celic so razdeljene v 4 skupine. Priporočila v novi klasifikaciji niso več obvezna, saj je odločitev o nadaljnji obravnavi žensk z nekaterimi spremembami odvisna tudi od HPV-testiranja. Obvezni postopki so zapisani v Smernicah za celostno obravnavo žensk s predrakavimi spremembami materničnega vratu.
Ključne besede: onkologija, citologija, diagnostika, maternični vrat
DiRROS - Objavljeno: 31.08.2018; Ogledov: 2487; Prenosov: 596
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