1. Quality and safety of botanical food products and their labellingAnita Kušar, Igor Pravst, 2014, original scientific article Keywords: botanicals, plants, quality, safety, labelling, health claims, food
Published in DiRROS: 29.01.2026; Views: 117; Downloads: 41
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2. Content validity and internal reliability of Slovene version of Medication Administration Error SurveyDominika Vrbnjak, Dušica Pahor, Gregor Štiglic, Majda Pajnkihar, 2016, original scientific article Abstract: Introduction: In Slovenia there is a lack of valid and reliable instruments for measuring medication administration errors. The aim of research is to determine the content validity and internal reliability of the Slovenian version of the ''Medication Administration Error Survey''. Methods: We used the translation and back translation tested the questionnaire for its content validity on the basis of an agreement of eight experts. Content validity was quantified by the content validity index and a modified Cohen kappa index. A cross-sectional design, with a convenience sample of 91 caregivers working in internal or surgical wards in two health care institutions, was used to test the internal consistency by calculating Cronbach's alpha and corrected item-total correlations. Results: 64 items showed an excellent content validity index, ranging from 0.875 to 1.000, and modified kappa index over 0.740. Two items had a content validity index 0.750 and modified kappa index 0.560. The average content validity index for three main parts of the questionnaire ranged from 0.940 to 0.959. Cronbach's alpha for these three parts ranged from 0.832 to 0.989. The corrected item-total correlations reached a required criterion for all items, except one. Discussion and conclusion: Instrument has an acceptable content validity and internal reliability, however, due to some methodological shortcomings results should be interpreted with caution. Further psychometric testing is needed.
Keywords: patients, safety, instruments development, psychometric properties, hospitals
Published in DiRROS: 28.01.2026; Views: 148; Downloads: 24
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3. Nurses' impact on quality of care : lessons from RN4CASTWalter Sermeus, 2015, original scientific article Abstract: Introduction: The RN4CAST - study (acronym for Nurse Forecasting in Europe) was launched in 2009 and ended in 2011 under the European Union's Seventh Framework Programme. The aim of the RN4CAST-study was to study how features of work environments and qualifications of the nurse workforce impact nurse retention, burnout among nurses and patient outcomes. Methods: The study was conducted in twelve European countries and was conducting a cross-sectional survey in 500 hospitals in which more than 33,000 nurses and more than 11,000 patients were involved. These data were linked to patient outcome data from administrative databases. Results: The study showed that patient outcomes such as patient mortality and patient satisfaction is highly related to nurse staffing characteristics such as patient-to-nurse ratios, nurse qualification and nursing work environment. Also nurse outcomes such as burnout, intention-to-leave, job satisfaction are related to staffing adequacy and nursing work environment. Discussion and conclusion: The RN4CAST study generated a large evidence base of nurse workforce issues across European health systems which is quite unique in terms of the number and qualification of nursing staff, the quality of working environments, burnout rates, job satisfaction rates, intention-to-leave rates that can be used for policy making.
Keywords: patient safety, nurses, recruitment, retention, staffing, qualification, work environment, burnout
Published in DiRROS: 28.01.2026; Views: 161; Downloads: 35
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5. The prevalence of violence directed at paramedic services personnelBranko Gabrovec, 2015, original scientific article Abstract: Introduction: Providers of health care are frequently subject to violence. The purpose of this research is to identify the type of violence suffered by first responders and the frequency of violence, since there is a lack of research in this area. Methods: A non-experimental sampling research method was used for this research; the research instrument is a structured questionnaire. We invited 36 rescue stations in Slovenia to participate, and 29 responded to the request; 246 questionnaires (68.3 %) were returned out of a total of 360. Data were analysed by means of descriptive statistics, correlation, the Kolmogorov-Smirnov test, Pearson's chi-square test, Mann-Whitney U test and linear regression with a significance of p < 0.05. Results: Seventy-eight per cent of respondents reported they had been verbally abused by their patients in the reporting year, while 49.6 % respondents reported they had been physically abused and 26.8 % of all respondents suffered injuries inflicted by patients. In the reporting year, 24.4 % of respondents experienced sexual harassment. A correlation was established between facing and experiencing fear (p = 0.017), between physical violence and feelings of vulnerability (p = 0.005), and between experiencing physical violence by the patient and lack of knowledge of how to manage patients' aggression (p = 0.012). Discussion and conclusion: The research could serve as a basis for a comprehensive approach to aggression management for nursing care professionals in paramedic services.
Keywords: nursing, paramedic, safety
Published in DiRROS: 28.01.2026; Views: 152; Downloads: 52
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6. Safety of ferrite nanoparticles for biomedical applications: cyto- and genotoxic effects of MxFe3-xO4 (M = Fe, Zn, Mn) in an advanced 3D human hepatic in vitro modelIza Rozman, Álvaro Gallo-Cordova, María del Puerto Morales, Marco A. Morales Ovalle, Gerardo F. Goya, Katja Kološa, Domen Hočevar, Bojana Žegura, Alja Štern, 2026, original scientific article Abstract: Given the growing interest in nanosized spinel-type ferrite nanoparticles for biomedical applications and the limited information on their safety, this study aimed to assess their cellular and genotoxic effects in an in vitro 3D human hepatic cell model (HepG2 spheroids). Ferrite nanoparticles – γFe2O3 (FeNPs; 14 ± 4 nm), Zn0.7Fe2.3O4 (ZnNPs; 14 ± 5 nm), and Mn0.4Fe2.6O4 (MnNPs; 7 ± 2 nm) – were synthesised through a microwave-assisted polyol route, functionalized with citric acid, and characterised using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES), Transmission Electron Microscopy (TEM), X-ray Diffraction (XRD), and Fourier Transform Infrared Spectroscopy (FTIR). Nanoparticle uptake was analysed using TEM, cytotoxicity was measured with CellTiter-Glo®, and oxidative stress induction was assessed using the 2′,7′-Dichlorodihydrofluorescein diacetate (DCFH-DA) and malondialdehyde (MDA) assay. Genotoxic effects were evaluated using the comet, γH2AX and p-H3 assays. Cellular stress responses were assessed using toxicogenomic analysis. Significant cytotoxicity of the tested nanoparticles (0.1–250 µg/mL) was observed; however, TEM analysis revealed limited penetration to the outermost cell layers of spheroids. Notably, only FeNPs induced ROS generation, while MDA levels remained unchanged in all tested samples. Low DNA damage was detected at 24 h, but a significant increase was observed at 96 h (5–50 µg/mL). No increase in γH2AX or p-H3 was found. No substantial alterations in DNA damage or oxidative stress-response gene expression were detected. Altogether, our findings suggest that the effects of ferrite nanoparticles are time- and composition-dependent, underlining the importance of further mechanistic and chronic exposure evaluations in 3D cell models.
Keywords: DNA damage, genotoxicity, HepG2 spheroids, magnetic ferrite-based nanoparticles, ROS induction, safety assessment, toxicogenomics
Published in DiRROS: 27.01.2026; Views: 101; Downloads: 79
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7. A review of safety issues in lithium-ion battery transportation process : research advances and challengesLulu Song, Zhenhua Wang, Yongchun Zhu, Zhizuan Zhou, Boxuan Wang, Dong Wang, Wilson Ulises Rojas Alva, Lizhong Yang, Xiaoyu Ju, 2026, review article Abstract: The growing demand for lithium-ion battery transportation, coupled with inadequate regulatory frameworks, has led to frequent fire incidents during transit, resulting in substantial losses of life and property. These recurring accidents underscore the urgent need to enhance the safety of lithium-ion batteries throughout the transportation process. This review begins by identifying key factors affecting battery safety during transport, such as mechanical abuse, thermal abuse, air pressure variations, and salt concentration. It then synthesizes current technological advancements and real-world battery transportation scenarios to conduct a targeted analysis of the critical technical challenges constraining transportation safety limits—specifically, ventilation and heat dissipation strategies, thermal monitoring, and fire safety design—while systematically examining the limitations of existing research. Accordingly, the paper proposes actionable recommendations and technical measures to improve the safety of lithium-ion battery transportation. Additionally, it outlines existing international standards and testing protocols governing lithium-ion battery transport and highlights shortcomings in the current regulatory landscape. The insights presented herein could provide valuable guidance for optimizing safety protocols in the transportation of lithium-ion batteries.
Keywords: lithium-ion batteries, transportation safety, thermal runaway, fire safety
Published in DiRROS: 27.01.2026; Views: 127; Downloads: 74
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8. The role of hydrogen in mining decarbonisationNina Lokar, Miguel Muñoz Ortiz, Amira Rachah, Ahmed Tazrin, Espen Vinge Fanavoll, Xiang Ma, Blaž Likozar, 2026, review article Keywords: hydrogen mining, decarbonisation, hydrogen-powered vehicles, hydrogen safety, energy system modeling
Published in DiRROS: 18.01.2026; Views: 196; Downloads: 112
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9. Experimental and numerical investigation of the fire behavior of double-glass building integrated photovoltaic modules with PVB interlayersWanning Yu, Lizhong Yang, Xinyang Wang, Dimeng Lai, Grunde Jomaas, Kim M. Liew, Xiaoyu Ju, 2026, original scientific article Abstract: Amid rising global energy demands and environmental concerns, energy-efficient, or ‘green’, buildings are becoming mandatory in building regulations worldwide. In that context, building-integrated photovoltaics (BIPV), which merge photovoltaic (PV) modules with architectural design, are gaining widespread adoption. To assess fire safety aspects of BIPV, the fire performance of double-glass PV modules with polyvinyl butyral (PVB) encapsulation in BIPV façade systems was studied experimentally and numerically. More specifically, fire experiments were conducted under varying radiative heat fluxes to evaluate thermal degradation, fire behavior, and toxic gas emissions. Key parameters, including ignition time, heat release rate per unit area (HRRPUA), mass loss rate (MLR), and gas composition, were analyzed. The results confirm that a higher external heat flux markedly reduces ignition time while increasing HRRPUA and MLR for BIPV, which is in line with results for other materials. The primary toxic gases emitted during combustion were CO, CO2, H2, and SO2, with CO and CO2 emissions rising significantly at elevated heat fluxes. To complement the experimental results, a numerical model coupling transient heat conduction and pyrolysis kinetics was developed to predict the pre-ignition thermal response of the multilayer structure. The model employed layer discretization and temperature-dependent boundaries, demonstrating close agreement with experimental data. Therefore, it enabled systematic analyses of the sensitivity of PV module material flammability to incident radiative heat fluxes, material properties, and geometric configurations. This combined experimental and numerical approach offers a predictive framework for assessing fire risks and optimizing the fire safety design of BIPV systems.
Keywords: fire behavior, combustion stages, PV modules, heat conduction pyrolysis model, module toxicity, fire safety
Published in DiRROS: 13.01.2026; Views: 113; Downloads: 73
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10. Stomach cancer elective surgery morbidity and mortality at 90-Day (Hold Study) : a prospective, international collaborative cohort studyClaudia Neves-Marques, Mohamed Abulazayem, Geoffrey Yuet Mun Wong, Ricardo David Maldonado, Yirupaiahgari Viswanath, Jan Grosek, Jurij Aleš Košir, 2026, original scientific article Abstract: Background: Data on multinational 90-day mortality and morbidity rates after surgery for gastric cancer is limited in the literature. This study aimed to understand the 90-day mortality and morbidity outcomes among patients undergoing elective gastric cancer surgery, as in the GASTRODATA Registry, and to identify associated risk factors. Methods: We conducted an international prospective study on patients aged ≥ 18 years undergoing elective surgery for gastric cancer with curative intent from January 4 to September 30, 2022. Known metastatic disease, concurrent secondary cancers, gastrointestinal stromal tumour (GIST) and Siewert type I/II oesophagogastric junction malignancies were excluded. Univariate and multivariate logistic regression were used to identify variables associated with the 90-day outcome. Results: 380 collaborators from 47 countries submitted data on 1538 patients. Median age was 65 years (IQR: 19–94), and 58.5% were males. 90-day morbidity and mortality rates were 38.2% (n = 587) and 2.9% (n = 45), respectively. Pre-operative higher Charlson Comorbidity Index, higher ASA score, pre-operative weight loss > 10%, positive specimen margin, and post-operative pathological IV staging (p value < 0.05) were significantly associated with clinically relevant complications and mortality. Conclusion: Elective gastric cancer surgery has a 90-day morbidity of 38.2% and a 90-day mortality of 2.9% globally. This study provided the most comprehensive international 90-day prospective data to date regarding gastric cancer surgery. Several factors associated with higher morbidity were identified, highlighting the importance of a unified language on surgical morbidity, prehabilitation, and ongoing audits to enhance patient outcomes.
Keywords: gastric cancer, elective surgery, morbidity, mortality, 90-day postoperative outcomes, multinational audit, surgical complications, anastomotic leaks, patient safety
Published in DiRROS: 16.12.2025; Views: 287; Downloads: 109
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