1. Identification of women with high grade histopathology results after conisation by artificial neural networksMarko Mlinarič, Miljenko Križmarić, Iztok Takač, Alenka Repše-Fokter, 2022, original scientific article Abstract: Background: The aim of the study was to evaluate if artificial neural networks can predict high-grade histopathology results after conisation from risk factors and their combinations in patients undergoing conisation because of pathological changes on uterine cervix. Patients and methods: We analysed 1475 patients who had conisation surgery at the University Clinic for Gynaecology and Obstetrics of University Clinical Centre Maribor from 1993-2005. The database in different datasets was arranged to deal with unbalance data and enhance classification performance. Weka open-source software was used for analysis with artificial neural networks. Last Papanicolaou smear (PAP) and risk factors for development of cervical dysplasia and carcinoma were used as input and high-grade dysplasia Yes/No as output result. 10-fold cross validation was used for defining training and holdout set for analysis. Results: Baseline classification and multiple runs of artificial neural network on various risk factors settings were performed. We achieved 84.19% correct classifications, area under the curve 0.87, kappa 0.64, F-measure 0.884 and Matthews correlation coefficient (MCC) 0.640 in model, where baseline prediction was 69.79%. Conclusions: With artificial neural networks we were able to identify more patients who developed high-grade squamous intraepithelial lesion on final histopathology result of conisation as with baseline prediction. But, characteristics of 1475 patients who had conisation in years 1993-2005 at the University Clinical Centre Maribor did not allow reliable prediction with artificial neural networks for every-day clinical practice.
Keywords: artificial neural networks, conisation, uterine cervical cancer, uterine cervical dysplasia, displazija materničnega vratu, rak materničnega vratu, konizacija, umetne nevronske mreže
Published in DiRROS: 24.07.2024; Views: 580; Downloads: 416
 Full text (663,31 KB)
This document has many files! More... |
2. |
3. |
4. Poročilo o poteku študije za uvajanje tekočinske tehnologije v SlovenijiVeronika Kloboves-Prevodnik, Mojca Florjančič, Tine Jerman, Jerneja Kos, Urška Ivanuš, 2021, published scientific conference contribution Keywords: epidemija, presejalni programi, rak materničnega vratu, citopatologija
Published in DiRROS: 16.03.2022; Views: 1276; Downloads: 722
Full text (763,17 KB)
This document has many files! More... |
5. |
6. |
7. |
8. |
9. |
10. |
