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Query: "keywords" (Li doping) .

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Metabolic consequences of anabolic steroids, insulin, and growth hormone abuse in recreational bodybuilders : implications for the world anti-doping agency passport
Filippo Giorgio Di Girolamo, Chiara Biasinutto, Alessandro Mangogna, Nicola Fiotti, Pierandrea Vinci, Rado Pišot, Filippo Mearelli, Boštjan Šimunič, Chiara Roni, Gianni Biolo, 2024, original scientific article

Abstract: Background Hormonal doping in recreational sports is a public-health concern. The World Anti-Doping Agency (WADA) promoted the creation of the Athlete Biological Passport, aiming to monitor athlete’s biological variables over time to facilitate indirect detection of doping. Detection tests for anabolic androgenic steroids (AAS) and growth hormone (GH) are available while insulin abuse cannot be revealed. We have determined in recreational bodybuilders the metabolic effects associated with different patterns of hormone abuse. All analyses were conducted using Statistical Package for Social Sciences (SPSS) 21.0 software (SPSS Chicago, IL). Results We have assessed plasma concentrations of selected metabolic markers and fatty acid content in erythrocyte membranes of 92 male bodybuilders and in 45 healthy controls. Hormonal abuse was identified by anonymous questionnaires. 43% (%) of recruited bodybuilders regularly abused hormones, i.e., anabolic androgenic steroids (95%) often associated with GH (30%) and/or insulin (38%). HDL-cholesterol was lower in insulin and/or GH abusers. Alanine (ALT) and aspartic (AST) transaminases were greater in hormone abusing bodybuilders than in non-doping bodybuilders and controls. Insulin doping was selectively associated with increased plasma ALT-to-AST ratio. In erythrocyte membranes, elongase activity (i.e., stearic-to-palmitic ratio) was lower in insulin and/or growth hormone doping, whereas increased Δ-9 desaturase activity (i.e., palmitoleic-to-palmitic ratio) was selectively associated with insulin doping. Conclusions In conclusion, our study demonstrates that insulin and GH abuse are characterized by multiple alterations of specific metabolic markers. Although further studies are needed to test whether longitudinal monitoring of selected metabolic marker such as muscle contraction time, HDL levels, ALT-AST ratio as well as the activities of selected enzymes (e.g. Δ-9 desaturase and elongase), could contribute to the detection of insulin and GH abuse in sport.
Keywords: bodybuilders, doping, drug abuse, matabolism
Published in DiRROS: 03.04.2024; Views: 42; Downloads: 21
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3.
Metal and non-metal modified titania : the effect of phase composition and surface area on photocatalytic activity
Boštjan Žener, Lev Matoh, Martin Reli, Andrijana Sever Škapin, Romana Cerc Korošec, 2022, original scientific article

Abstract: The application of TiO 2 photocatalysis in various environmental fields has been extensively studied in the last decades due to its ability to induce the degradation of adsorbed organic pollutants. In the present work, TiO 2 powders doped and co-doped with sulfur and nitrogen and modified with platinum were prepared by particulate sol-gel synthesis. PXRD measurements revealed that the replacement of HCl with H 2SO4 during synthesis reduced the size of the crystallites from ~ 30 nm to ~20 nm, increasing the surface area from ~44 m2/g to ~80 m2/g. This is consistent with the photocatalytic activity of the samples and the measured photocurrent behavior of the photocatalysts. The results showed that the prop- erties of the powders (i.e., surface area, crystallite size, photocurrent behavior) depend strongly not only on the type but also on the amount of acid and dopants used in the synthesis. Doping, co-doping and modification of TiO 2 samples with nitrogen, sulfur and platinum increased their photocatalytic activity up to 6 times.
Keywords: titanium dioxide, powders, doping, photocatalysis, photocurrent, SEM
Published in DiRROS: 04.05.2023; Views: 304; Downloads: 130
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4.
Dielectric loss of Si[sub]2N[sub]2O and the influence of Li on its properties
Yong Yang, Ming He, Ting Zhang, Meng-qiang Wu, 2022, original scientific article

Keywords: Si2N2O, dielectric loss, high temperature, Li doping
Published in DiRROS: 22.06.2022; Views: 448; Downloads: 204
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5.
Odvzem vzorcev za kontrolo dopinga
Joško Osredkar, 2009, not set

Keywords: laboratorijska diagnostika, odvzem vzorcev, urin, doping, doping kontrola, šport, športna medicina
Published in DiRROS: 29.04.2016; Views: 4630; Downloads: 696
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6.
Boj proti dopingu v kolesarstvu
Lovro Žiberna, 2014, professional article

Keywords: kolesarstvo, doping
Published in DiRROS: 15.04.2016; Views: 4069; Downloads: 693
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