1. Urinary proteomics and systems biology link eight proteins to the higher risk of hypertension and related complications in Blacks versus WhitesDe-Wei An, Dries S. Martens, Gontse G. Mokwatsi, Yu-Ling Yu, Babangida S. Chori, Agnieszka Latosinska, Godsent Isiguzo, Susanne Eder, Dong-Yan Zhang, Gert Mayer, Jana Brguljan, 2025, original scientific article Abstract: Blacks are more prone to salt-sensitive hypertension than Whites. This cross-sectional analysis of a multi-ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension-related complications. The study included individuals enrolled in African Prospective Study on the Early Detection and Identification of Cardiovascular Disease and Hypertension (African-PREDICT), Flemish Study of the Environment, Genes and Health Outcomes (FLEMENGHO), Prospective Cohort Study in Patients with Type 2 Diabetes Mellitus for Validation of Biomarkers (PROVALID)-Austria, and Urinary Proteomics Combined with Home Blood Pressure Telemonitoring for Health Care Reform Trial (UPRIGHT-HTM). Sequenced urinary peptides detectable in 70% of participants allowed the identification of parental proteins and were compared between Blacks and Whites. Of 513 urinary peptides, 300 had significantly different levels among healthy Black (n = 476) and White (n = 483) South Africans sharing the same environment. Analyses contrasting 582 Blacks versus 1731 Whites, and Sub-Saharan Blacks versus European Whites replicated the findings. COL4A1, COL4A2, FGA, PROC, MGP, MYOCD, FYXD2, and UMOD were identified as the most likely candidates underlying the racially different susceptibility to salt sensitivity, hypertension, and related complications. Enriched pathways included hemostasis, platelet activity, collagens, biology of the extracellular matrix, and protein digestion and absorption. Our study suggests that MGP and MYOCD being involved in cardiovascular function, FGA and PROC in coagulation, FYXD2 and UMOD in salt homeostasis, and COL4A1 and COL4A2 as major components of the glomerular basement membrane are among the many proteins potentially incriminated in the higher susceptibility of Blacks compared to Whites to salt sensitivity, hypertension, and its complication. Nevertheless, these eight proteins and their associated pathways deserve further exploration in molecular and human studies as potential targets for intervention to reduce the excess risk of hypertension and cardiovascular complications in Blacks versus Whites.
Keywords: cardiovascular disease, hypertension, population science, salt sensitivity, urinary proteome
Published in DiRROS: 20.04.2026; Views: 160; Downloads: 110
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2. Decoding polarity gradient enabled ultra-high lithium ion conductionYuqing Chen, Aiping Wang, Yun Zhao, Wei Wang, Robert Dominko, Peitao Xiao, Peng Gao, Yan Duan, Baohua Li, Xiangming He, Jilei Liu, 2026, original scientific article Published in DiRROS: 10.03.2026; Views: 376; Downloads: 197
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6. deadtrees.earth — An open-access and interactive database for centimeter-scale aerial imagery to uncover global tree mortality dynamicsClemens Mosig, Janusch Vajna-Jehle, Miguel D. Mahecha, Yan Cheng, Henrik Hartmann, David Montero, Samuli Junttila, Stephanie Horion, Mirela Beloiu Schwenke, Michael J. Koontz, 2026, original scientific article Abstract: Excessive tree mortality is a global concern and remains poorly understood as it is a complex phenomenon. We lack global and temporally continuous coverage on tree mortality data. Ground-based observations on tree mortality, e.g., derived from national inventories, are very sparse, and may not be standardized or spatially explicit. Earth observation data, combined with supervised machine learning, offer a promising approach to map overstory tree mortality in a consistent manner over space and time. However, global-scale machine learning requires broad training data covering a wide range of environmental settings and forest types. Low altitude observation platforms (e.g., drones or airplanes) provide a cost-effective source of training data by capturing high-resolution orthophotos of overstory tree mortality events at centimeter-scale resolution. Here, we introduce deadtrees.earth, an open-access platform hosting more than two thousand centimeter-resolution orthophotos, covering more than 1,000,000 ha, of which more than 58,000 ha are manually annotated with live/dead tree classifications. This community-sourced and rigorously curated dataset can serve as a comprehensive reference dataset to uncover tree mortality patterns from local to global scales using space-based Earth observation data and machine learning models. This will provide the basis to attribute tree mortality patterns to environmental changes or project tree mortality dynamics to the future. The open nature of deadtrees.earth, together with its curation of high-quality, spatially representative, and ecologically diverse data will continuously increase our capacity to uncover and understand tree mortality dynamics.
Keywords: orthophoto, drone, tree mortality, remote sensing, database, citizen science, forests
Published in DiRROS: 16.01.2026; Views: 366; Downloads: 243
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7. Effects of manganese dioxide and sintering temperature on the properties and microstructure of a secondary-aluminum-ash ceramic proppantYongming Zeng, Naichen Xiao, Haiping Yang, Peipeng Yang, Fei Yan, Sifeng Bi, Ruien Yu, 2025, original scientific article Keywords: ceramic proppant, secondary aluminum ash, crushing rate, microstructure
Published in DiRROS: 08.10.2025; Views: 686; Downloads: 339
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8. Data from : Physical constraints and environmental factors shape phloem anatomical traits in woody angiosperm speciesYan Wang, Johannes Liesche, Alan Crivellaro, Jiří Doležal, Jan Altman, Donato Chiatante, Anastazija Dimitrova, Ze-Xin Fan, Peili Fu, Félix Forest, Jožica Gričar, 2025, complete scientific database of research data Abstract: We collected main stem or branch cross-sections of 188 angiosperm woody species, which represent a wide range of climates and diverse families. Measurements of xylem vessel and phloem sieve element diameter, density, and lumen fraction were used in phylogenetic structural equation models to disentangle internal and climatic constraints on their morphological and anatomical features.
Keywords: adaptation, allometry, phloemsieve element, xylem vessel
Published in DiRROS: 25.09.2025; Views: 521; Downloads: 264
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9. Physical constraints and environmental factors shape phloem anatomical traits in woody angiosperm speciesYan Wang, Johannes Liesche, Alan Crivellaro, Jiří Doležal, Jan Altman, Donato Chiatante, Anastazija Dimitrova, Ze-Xin Fan, Peili Fu, Félix Forest, Jožica Gričar, 2025, original scientific article Abstract: Xylem trait studies have enhanced our understanding of how plants strategically adapt their morphological and anatomical features to diverse climates. Despite the importance of the phloem in plant functioning, similar studies of phloem traits are lacking. To tackle this knowledge gap, we analyzed phloem anatomical traits of woody angiosperm species in relation to climate and the distance of samples to the stem tip. We collected main stem or branch cross-sections of 188 angiosperm woody species, which represent a wide range of climates and diverse families. Measurements of xylem vessel and phloem sieve element diameter, density, and lumen fraction were used in phylogenetic structural equation models to disentangle internal and climatic constraints on their morphological and anatomical features. Our results showed that distance-to-tip mainly affects sieve element and vessel diameter and density, while climate more strongly influenced conduit lumen fraction. Vessel size was positively correlated with temperature after correcting for the distance-to-tip, while sieve element diameter was correlated with water availability. Our results highlight the need to account for distance-to-tip when accessing anatomical variations linked to the environment, and show that sieve element traits respond to other climatic drivers than vessel traits rather than simply mirroring them.
Keywords: adaptation, allometry, phloemsieve element, tip-to-base conduit widening, xylem vessel
Published in DiRROS: 25.09.2025; Views: 476; Downloads: 332
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10. Load influence on the friction and wear behavior of arc ion plated Cr coatingsJinpeng Yang, Guanghui Wang, Haimin Yan, Zijun Wang, Cean Guo, Jian Zhang, 2025, original scientific article Keywords: friction and wear, Cr coating, arc ion plating, tribofilm
Published in DiRROS: 20.06.2025; Views: 807; Downloads: 453
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