1. Triple negative breast cancer : prognostic factors and survivalTanja Ovčariček, Snježana Frković-Grazio, Erika Matos, Barbara Možina, Simona Borštnar, 2011, original scientific article Abstract: Background. Triple negative breast cancer (TNBC) is defined by a lack of expression of both estrogen (ER) and progesteron(PgR) receptors as well as human epidermal growth factor receptor 2 (HER2). Our retrospective analysis addressed prognostic factors for short- and long-term outcomes of patients (pts) with TNBC pts treated in routine clinical practice. Patient and methods.Our retrospective study included 269 TNBC treated at Institute of Oncology Ljubljana between March 2000 and December 2006. The collected data included patientsć, tumoursć and treatmentsć characteristics. The survival analyses were performed using the Kaplan-Meier method. The Cox proportional hazard model was used in the multivariate analysis. Results. The median age ofour patients was 55.3 yrs (23-88.5) and the median follow-up was 5.9 yrs (0.3-9.6). Six (2%) pts experienced local only, 79 (92%) pts distal recurrenceand 66 (24%) died. The predominant localisation of the first relapsewas in visceral organs (70.4%). The 5-year disease-free survival (DFS) for the entire group was 68.2% and the 5-year overall survival (OS) was 74.5%.We found a pattern of high recurrence rate in the first 3 years following the diagnosis and a clear decline in recurrence rate over the next 3years. In the univariate analysis age, nodal status, size and lymphovascular invasion (LVI) were found to have a significant impact on DFS as well as on OS. In the multivariate analysis only age (HR=1.79; 95%CI=1.14-2.82; p=0.012) and nodal status (HR=2.71; 95%CI=1.64-4.46; p<0.001) retained their independent prognostic value for DFS and for OS only the nodal status (HR=2.96; 95%CI=1.51-5.82; p=0.002). (Abstract truncated at 2000 characters)
Published in DiRROS: 19.03.2024; Views: 92; Downloads: 30
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3. Priporočila za obravnavo bolnikov z rakom debelega črevesa in danke2020, dictionary, encyclopaedia, lexicon, manual, atlas, map Keywords: rak debelega črevesa, rak danke, bolniki, zdravljenje
Published in DiRROS: 18.03.2022; Views: 788; Downloads: 429
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5. Državni presejalni program za raka dojk - DORA : poročilo za obdobje: oktober 2007-julij 2008Maja Primic-Žakelj, Mateja Krajc, Gorazd Noč, Maksimiljan Kadivec, Kristijana Hertl, Snježana Frković-Grazio, Janez Žgajnar, Aljoša Rojec, Marija Seljak, Blanka Mikl Mežnar, Anže Drolc, Tomaž Grbec, 2008, final research report Published in DiRROS: 26.03.2021; Views: 1087; Downloads: 346
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6. Smernice za obravnavo bolnic z rakom jajčnikov, jajcevodov in s primarnim peritonealnim seroznim rakomMatija Barbič, Sonja Bebar, Olga Cerar, Branko Cvjetičanin, Janka Čarman, Astrid Djurišić, Snježana Frković-Grazio, Barbara Gazić, Andreja Gornjec, Katja Jakopič, Borut Kobal, Mateja Krajc, Sebastjan Merlo, Maja Marolt-Mušič, Maja Pakiž, Špela Smrkolj, Manja Šešek, Erik Škof, Iztok Takač, Aleš Vakselj, Vesna Zadnik, Helena Barbara Zobec Logar, 2015, professional monograph Keywords: zdravstvena obravnava, smernice, rak jajčnikov, ginekologija, neoplazme, ginekološki raki
Published in DiRROS: 09.06.2020; Views: 1717; Downloads: 542
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8. Smernice za obravnavo bolnikov z malignimi limfomiMarta Dremelj, Snježana Frković-Grazio, Monika Jagodic, Janez Jančar, Barbara Jezeršek Novaković, Tanja Južnič Šetina, Veronika Kloboves-Prevodnik, Radka Tomšič, Marjeta Vovk, Lorna Zadravec-Zaletel, 2008, dictionary, encyclopaedia, lexicon, manual, atlas, map Published in DiRROS: 27.05.2020; Views: 1621; Downloads: 490
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9. Postopki za obravnavo bolnic z rakom jajčnikov, jajcevodov in s primarnim peritonealnim seroznim rakomMatija Barbič, Sonja Bebar, Olga Cerar, Branko Cvjetičanin, Janka Čarman, Astrid Djurišić, Snježana Frković-Grazio, Barbara Gazić, Andreja Gornjec, Katja Jakopič, Borut Kobal, Mateja Krajc, Sebastjan Merlo, Maja Marolt-Mušič, Maja Pakiž, Špela Smrkolj, Manja Šešek, Erik Škof, Iztok Takač, Aleš Vakselj, Vesna Zadnik, Helena Barbara Zobec Logar, 2015, professional monograph Keywords: zdravstvena obravnava, rak jajčnikov, ginekologija, neoplazme, ginekološki raki
Published in DiRROS: 27.05.2020; Views: 1853; Downloads: 566
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