20.500.12556/DiRROS-8863 Prediagnosticiranje Overdiagnosis V tem prispevku bomo opisali pojav pri raku, ki ga po angleško imenujemo overdiagnosis. Za izraz še ni uradno sprejetega slovenskega prevoda, v tem prispevku pa bomo uporabili izraz prediagnosticiranje, ki označuje raka, ki ne bi povzročil simptomov ali smrti, če ne bi bil diagnosticiran. Za to sta potrebna 2 pogoja: obstoj večje baze subkliničnega raka in aktivno odkrivanje te baze, presejanje. Ocena prediagnosticiranja pri presejanju je znana iz randomiziranih študij: 25 % za raka dojk, 50 % za pljučnega raka in več kot 60 % za raka prostate. Retrospektivne študije in populacijska statistika kažejo na prediagnosticiranje pri nevroblastomu, ščitničnem raku, raku ledvic in melanomu. Zato je treba bolnike seznaniti z velikostjo problema in možnostmi negativnih učinkov zdravljenja bolezni, ki jih morda ne bi nikoli prizadela. Pogostost prediagnosticiranja bi bilo treba bolje oceniti in odkriti metode, s katerimi bi ta problem zmanjšali. In this article we will describe a phenomenon in cancer medicine known as overdiagnosis. As there is still no official Slovenian translation for this term, a Slovenian term “prediagnosticiranje” is used in the article, specifying cancer that does not cause symptoms or death if undiagnosed. This requires two conditions: an existence of a larger sub-clinical cancer base and active detection of this base, screening. Randomised studies have provided estimates of overdiagnosis in screening, being: 25% for breast cancer, 50% for lung cancer, and more than 60% for prostate cancer. Restrospective studies and population statistics show overdiagnosis of neuroblastoma, thyroid cancer, kidney cancer and melanoma. Therefore, the patients must be informed of the size of the problem and the possible negative effects of treatment of this disease, which might otherwise never have affected them at all. Thus, it would be necessary to provide better estimates of overdiagnosis frequency and discover the methods to minimise this problem. true false true Slovenski jezik Angleški jezik by Authors Neznano 2018-08-31 13:31:56 2018-08-31 13:31:56 2022-08-24 17:38:23 0000-00-00 00:00:00 2012 0 0 str. 29-32, 58 št. 1 Letn. 16 jun. 2012 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-006.6-07 1408-1741 URN:NBN:SI:doc-OK91AHTJ 1318523 65324032 RAZ_Glumac_Nebojsa_i2012.pdf RAZ_Glumac_Nebojsa_i2012.pdf 1 B8B1727791BFAE99FDD6D0D6DC2E18C5 0521f818a031cf6f8af725cac25a476f7180eedcec6f9ab6b2556e9e284518e9 6314ab72-17b5-11ed-b6b8-001a4af901a5 20.500.12556/dirros/66975dd2-7f95-4caa-8cc1-6159ac6d2639 https://dirros.openscience.si/Dokument.php?lang=slv&id=10644 Onkološki inštitut Ljubljana Onkologija : strokovni časopis za zdravnike 0 0 0