20.500.12556/DiRROS-8793 Prizadetost pljuč in srca po obsevanju ter kemoterapiji Hodgkinove bolezni Lung and heart impairment after irradiation and chemotherapy for Hodgkin's disease - a case study Akutne in kronične okvare pljuč po zdravljenju raka v otroštvu so po sodobnem zdravljenju redke in običajno brez kliničnih znakov ter simptomov. Pri bolnici, ki je bila v otroštvu zdravljena zaradi Hodgkinovega limfoma z obsevanjem vratu, supraklavikularnih bezgavk in mediastinuma ter s kemoterapijo, so kvarne posledice verjetna kombinacija neugodnih učinkov tega zdravljenja na srce in pljuča. Pri naši bolnici je glede na potek in napredovanje pljučne prizadetosti v ospredju vaskularna prizadetost - pljučna vaskulopatija, ki je bila s histološkim pregledom bioptata pljučnega tkiva tudi potrjena. Pri opisu želimo opozoriti na kroničen ter progredienten potek bolezni, ki terja zahtevno obravnavo specialistov in 22 let po zdravljenju povzroča težko invalidnost. Acute and chronic defects following childhood cancer treatment are rare with modern treatment techniques and usually without any clinical signs and symptoms. In a patient who was treated for childhood Hodgkin's lymphoma with irradiation to the neck, supraclavicular lymph nodes and mediastinum and chemotherapy, the consequences include a probable combination of adverse effects of this treatment on the lungs and heart. Considering the course and progression of lung impairment, vascular impairment - pulmonary vasculopathy was found to be at the forefront in our patient, which was confirmed by histological examination of the lung-tissue bioptat. By describing this case, we wish to point to the chronic and progredient course of the disease which requires complex management by specialists and causes severe disability 22 years after treatment. Hodginova bolezen otroci posledice pljuča bolezni dihal true false true Slovenski jezik Angleški jezik by Authors Neznano 2018-08-31 13:30:28 2018-08-31 13:30:29 2022-08-24 17:30:52 0000-00-00 00:00:00 2013 0 0 str. 70-72, 78 št. 1 Letn. 17 jun. 2013 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.24-006.6-08 1408-1741 URN:NBN:SI:doc-1ZYP7900 1556347 65324032 RAZ_Zadravec-Zaletel_Lorna_i2013.pdf RAZ_Zadravec-Zaletel_Lorna_i2013.pdf 1 83013892CF69531DB205B9CE1514B1F2 da8025ec3c70081b48635083fa352fc66fe1dfa6dd1fe095477f70104e47fd50 5e7d0f99-17b5-11ed-b6b8-001a4af901a5 20.500.12556/dirros/be9d6c81-0e4c-4ee8-90b9-153e92af7203 https://dirros.openscience.si/Dokument.php?lang=slv&id=10574 Onkološki inštitut Ljubljana Onkologija : strokovni časopis za zdravnike 0 0 0