20.500.12556/DiRROS-8593 Cirkulirajoče tumorske celice in njihov pomen pri raku dojke : pregled izsledkov dosedanjih raziskav Circlulation of tumor cells and their effect on breast cancer – reviewing the results of previous studies Circulating tumor cells (CTCs) are epithelial tumor cells detected in the peripheral blood of patients with solid malignant tumors. They originate from the primary tumor or metastatic sites. New techniques have been developed to isolate and characterise these cells, including the FDA-approved CellSearch, which are using mainly cytometric/antibody-based and molecular approaches. Recent advances in theories regarding metastasis support the role of early release of tumor cells in the neoplastic process. It has been found that phenotypic variation exists between the primary tumor and CTCs. Of particular interest is the difference found between primary tumor and CTC HER-2 status in both metastatic and early breast cancer. CTC enumeration has been incorporated into different fields of oncology as a prognostic marker, a tool to monitor therapy response, and a method to understand basic tumor characteristics. But currently, there is still no role for CTCs in clinical practice. tumor onkologija dojke prognoza zasevki true false true Slovenski jezik Angleški jezik by Authors Neznano 2018-08-31 13:26:19 2018-08-31 13:26:19 2022-08-16 10:06:06 0000-00-00 00:00:00 2011 0 0 str. 79-82 št. 2 Letn. 15 dec. 2011 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 618.19-006.6 1408-1741 URN:NBN:SI:doc-B98AV2ZQ 1194619 65324032 RAZ_Marinko_Tanja_i2011.pdf RAZ_Marinko_Tanja_i2011.pdf 1 7B6C7E1F7D10F51D50D5517FAB0E3F16 27f3145b45df60a982468e714f7dc85ae12319ea1f7e7759dbbea103ab5fe208 5164f3ad-17b5-11ed-b6b8-001a4af901a5 20.500.12556/dirros/5bc867a8-a621-4819-bb2a-28959edaf2ff https://dirros.openscience.si/Dokument.php?lang=slv&id=10374 Onkološki inštitut Ljubljana Onkologija : strokovni časopis za zdravnike 0 0 0