20.500.12556/DiRROS-31976 Flash glucose monitoring addition to self-monitoring of blood glucose and perinatal outcomes in gestational diabetes a randomized controlled trial Background: Self-monitoring of blood glucose represents the standard for glycemic monitoring in gestational diabetes mellitus, while the role of continuous glucose monitoring remains uncertain. Objective: To assess whether adjunctive flash glucose monitoring improves achievement of established self-monitored glucose targets compared with self-monitoring alone and to examine maternal and neonatal outcomes. Study Design: We conducted an open-label, single-center, randomized controlled trial comparing adjunctive flash glucose monitoring plus self-monitoring of blood glucose with self-monitoring of blood glucose alone. The prespecified primary outcome was the percentage of self-monitored glucose measurements within the established target range. Secondary outcomes included maternal and neonatal outcomes. Analyses followed the intention-to-treat principle. Results: A total of 205 women (median age, 32 years; median prepregnancy body mass index, 23.5 kg/m2; median gestational age, 27 weeks) were randomized (102 to adjunctive flash glucose monitoring and 103 to self-monitoring alone). The percentage of self-monitored glucose measurements within target range was lower in the adjunctive flash monitoring group (89.5% vs 92.6%, P=.04). Median fasting and 1-hour postprandial self-monitored glucose concentrations were comparable between groups and within recommended targets. The incidence of large-for-gestational-age infants was lower in the flash monitoring group (3% vs 11%; P=.05; odds ratio, 0.27; 95% confidence interval, 0.07–0.99). Conclusion: Adjunctive flash glucose monitoring did not improve glycemic outcome in this low-risk gestational diabetes population. However, it was associated with fewer large-for-gestational-age neonates, a secondary outcome that should be interpreted cautiously given the sample size and number of events. continuous glucose monitoring CGM gestational diabetes GDM large-for-gestational-age LGA flash glucose monitoring perinatal outcomes self-monitoring of blood glucose small-for-gestational-age neprekinjeno spremljanje glukoze gestacijski diabetes velika gestacijska telesna masa true false true Angleški jezik Slovenski jezik Neznano 2026-08-21 14:18:47 2026-08-21 14:18:48 2026-08-22 03:49:55 0000-00-00 00:00:00 2026 0 0 Nasl. z nasl. zaslona; Opis vira z dne 3. 4. 2026; str. 375-384 iss. 2 Vol. 235 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616.379 1097-6868 10.1016/j.ajog.2026.03.030 274118659 RAZ_Zorko_Klara_2026.pdf RAZ_Zorko_Klara_2026.pdf 1 539EC7BAE9CDF9F1B452E87B67E8F708 262152c9e0117630c8f8d295522793ed3b3c952101286a3ee8a726f754df2c1e 0879328a-9d5b-11f1-af5a-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=49793 https://www.ajog.org/article/S0002-9378(26)00180-8/fulltext 1 88a7d03a-9d5a-11f1-af5a-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=49789 Univerzitetni klinični center Ljubljana 0 0 0