20.500.12556/DiRROS-31316 Impact of cardiac arrest in patients with cardiogenic shock due to ST-elevation myocardial infarction Background: Cardiogenic shock (CS) frequently complicates ST-elevation myocardial infarction (STEMI) and may be associated with cardiac arrest occurring either as out-of-hospital (OHCA) or in-hospital cardiac arrest (IHCA). Aim: To compare clinical characteristics, coronary anatomy, management and survival among patients with CS without cardiac arrest (STEMI-CS-no CA), CS with OHCA (STEMI-CS-OHCA) and CS with IHCA (STEMI-CS-IHCA). Methods: We conducted a retrospective study including consecutive patients with CS and STEMI undergoing immediate coronary angiography and percutaneous coronary intervention (PCI) who were admitted to two tertiary university hospitals between 2016 and 2025. Results: Among 345 patients, 150 (43.5%) had STEMI-CS-no CA, 120 (34.8%) STEMI-CS-OHCA, and 75 (21.7%) STEMI-CS-IHCA. STEMI-CS-IHCA patients were older, less frequently presented with an initial shockable rhythm (36.0% vs 61.0%, p = 0.002) and had shorter time to return of spontaneous circulation (10.0 vs 19.6 min, p < 0.001) compared to STEMI-CS-OHCA. They had also lower arterial pressure, left ventricular ejection fraction, estimated glomerular filtration rate and higher arterial lactate compared to STEMI-CS-no CA and STEMI-CS-OHCA. Coronary complexity increased progressively with SYNTAX score rising from 18.6 in STEMI-CS-no CA to 21.5 in STEMI-CS-OHCA and to 27.2 in STEMI-CS-IHCA (p < 0.001). At 1-year, all-cause mortality was 67.3% in STEMI-CS-no CA, 78.3% in STEMI-CS-OHCA (p = 0.004) and 82.7% in STEMI-CS-IHCA (p < 0.001) without significant difference between cardiac arrest subgroups (p = 0.555). Conclusion: In STEMI-related CS, concomitant OHCA or IHCA is associated with distinct clinical profiles, coronary anatomy, intensity of treatment and markedly impaired long-term survival. cardiac arrest cardiogenic shock ischemia PCI prognosis STEMI ST-elevation myocardial infarction srčni zastoj kardiogeni šok ishemija perkutana koronarna intervencija (PCI) prognoza Akutni miokardni infarkt z dvigom veznice ST (STEMI) true false true Angleški jezik Slovenski jezik Neznano 2026-07-27 14:31:27 2026-07-27 14:31:28 2026-07-28 03:47:45 0000-00-00 00:00:00 2026 0 0 Nasl. z nasl. zaslona; Opis vira z dne 11. 5. 2026; str. 1-7 [article no.] 111094 Vol. 224 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 616-083.98 1873-1570 10.1016/j.resuscitation.2026.111094 277745411 RAZ_Franco_Danilo_2026.pdf RAZ_Franco_Danilo_2026.pdf 1 953CC87615C4CAAB05CA0B640E7094A4 07c436f20331d4a2b9361d550cca79008b937a48bf6c43ba842119828ba36058 32045e75-89b7-11f1-a255-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=48417 https://www.resuscitationjournal.com/article/S0300-9572(26)00140-1/fulltext 1 18537bce-89b7-11f1-a255-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=48416 Univerzitetni klinični center Ljubljana 0 0 0