20.500.12556/DiRROS-30581 Hormonske spremembe in vstop v pomenopavzo Hormonal changes and entering postmenopause Menarha in menopavza sta ključna fiziološka mejnika v življenju ženske, ki sprožita številne telesne in duševne spremembe. Leta 2011 je Svetovna zdravstvena organizacija posodobila nomenklaturo reproduktivnega staranja, ga razdelila na različne stadije in uvedla pojem menopavznega prehoda. Menopavzni prehod običajno nastopi okoli 40. leta starosti in prinaša številne hormonske spremembe in vpliv na menstruacijske cikluse. Zmanjša se tvorba anti-Müllerjevega hormona in estradiola, ki jima sledi naraščanje folikle stimulirajočega hormona. Zmanjšanje kakovosti jajčnih foliklov vodi v zmanjšanje plodnosti in odsotnost ovulacije, menstruacije pa postanejo neredne in podaljšane. Prehod v zgodnjo pomenopavzo opredeljuje zadnja menstruacija. Obdobje spremljajo težave s termoregulacijo, urogenitalne spremembe, večje tveganje za srčno-žilne bolezni in spremembe v psihičnem zdravju. V pozni pomenopavzi se hormonski nivoji stabilizirajo, a trajno vplivajo na splošno zdravje ženske. Menarche and menopause are key physiological milestones in a woman’s life, triggering many physical and mental changes. In 2011, the World Health Organization updated the nomenclature of reproductive aging, dividing it into different stages and introducing the concept of the menopausal transition. Menopausal transition usually occurs around the age of 40 and brings many hormonal changes and an impact on menstrual cycles. The formation of anti-Müllerian hormone and estradiol decreases, followed by an increase in follicle-stimulating hormone. A decrease in the quality of egg follicles leads to reduced fertility and the absence of ovulation, and periods become irregular and prolonged. The progression to early postmenopause is defined by the last menstrual period. The period is accompanied by problems with thermoregulation, urogenital changes, a higher risk of cardiovascular diseases and changes in psychological health. In late postmenopause, hormone levels stabilize, but they have a lasting impact on a woman’s overall health. hormonske spremembe pomenopavza menopavzni prehod hormonal changes postmenopause menopausal transition true false true Slovenski jezik Angleški jezik Neznano 2026-06-30 09:39:00 2026-06-30 09:39:11 2026-07-01 03:55:57 0000-00-00 00:00:00 2025 0 0 Besedilo v slov.; str. 92-97 Št. 2 Letn. 76 maj 2025 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2025-05-01 616.2 0014-8229 271038211 https://www.sfd.si/wp-content/uploads/2025/05/gersak_fv.pdf 0 e8ac105c-7456-11f1-9c8b-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46533 gersak_fv.pdf gersak_fv.pdf 1 2263BEFBC64545C5874C39C95249BD75 6b7db50a73df514da2d307e2b65be45f238176fad0eed3b47dfc0f2ce9e8cb4b c3643076-7456-11f1-9c8b-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46532 Slovensko farmacevtsko društvo Farmacevtski vestnik 0 0 0