20.500.12556/DiRROS-30461 Influence of different intraoperative fluid management on postoperative outcome after abdominal tumours resection Vpliv različnega intraoperativnega spremljanja tekočin na pooperativni izid po resekciji abdominalnih tumorjev Background: Intraoperative fluid management is a crucial aspect of cancer surgery, including colorectal surgery and pancreatoduodenectomy. The study tests if intraoperative multimodal monitoring reduces postoperative morbidity and duration of hospitalisation in patients undergoing major abdominal surgery treated by the same anaesthetic protocols with epidural analgesia. Patients and methods: A prospective study was conducted in 2 parallel groups. High-risk surgical patients undergoing major abdominal surgery were randomly selected in the control group (CG), where standard monitoring was applied (44 patients), and the protocol group (PG), where cerebral oxygenation and extended hemodynamic monitoring were used with the protocol for intraoperative interventions (44 patients). Results: There were no differences in the median length of hospital stay, CG 9 days (interquartile range [IQR] 8 days), PG 9 (5.5), p = 0.851. There was no difference in postoperative renal of cardiac impairment. Procalcitonin was significantly higher (highest postoperative value in the first 3 days) in CG, 0.75 mcg/L (IQR 3.19 mcg/L), than in PG, 0.3 mcg/L (0.88 mcg/L), p = 0.001. PG patients received a larger volume of intraoperative fluid; median intraoperative fluid balance +1300 ml (IQR 1063 ml) than CG; +375 ml (IQR 438 ml), p < 0.001. Conclusions: There were significant differences in intraoperative fluid management and vasopressor use. The median postoperative value of procalcitonin was significantly higher in CG, suggesting differences in immune response to tissue trauma in different intraoperative fluid status, but there was no difference in postoperative morbidity or hospital stay. abdominal surgery cerebral tissue oxygenation hemodynamic monitoring intraoperative monitoring true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik Neznano 2026-06-26 10:54:00 2026-06-26 10:54:00 2026-06-27 03:52:14 0000-00-00 00:00:00 2024 0 0 Soavtorji: Katarina Mencin, Vesna Novak-Jankovic , Alenka Spindler-Vesel; str. 279-288, XII no. 2 Vol. 58 Jun. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2024-06-01 61 1318-2099 10.2478/raon-2024-0015 190365443 https://sciendo.com/article/10.2478/raon-2024-0015 1 94bc43eb-713c-11f1-b414-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46261 RAZ_Jenko_Matej_2024.pdf RAZ_Jenko_Matej_2024.pdf 1 3E0E86D12BBE02D16921B79A082C1C4B c5d66ebe42488d9047f137feb6c9dde7046ab7f926789299ce6170fffbb302c0 c8acc481-713c-11f1-b414-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46262 Društvo radiologije in onkologije 0 0 0