20.500.12556/DiRROS-30436 The influence of anaesthesia on cancer growth Vpliv anestezije na rast tumorjev Oncological patients make up a large proportion of all surgical patients. Through its influence on the patient’s inflammatory and immune system, the choice of anaesthetic technique has an indirect impact on the health of the individual patient and on public health. Both the specific and the non-specific immune system have a major influence on the recurrence of carcinomas. The pathophysiological basis for growth and metastasis after surgery is the physiological response to stress. Inflammation is the organism’s universal response to stress. Anaesthetics and adjuvants influence perioperative inflammation in different ways and have an indirect effect on tumour growth and metastasis. In vitro studies have shown how individual anaesthetics influence the growth and spread of cancer, but clinical studies have not confirmed these results. Nevertheless, it is advisable to use an anaesthetic that has shown lesser effect on the growth of cancer cells in vitro. Conclusions In this review, we focus on the area of the effects of anaesthesia on tumour growth. The field is still relatively unexplored, there are only few clinical prospective studies and their results are controversial. Based on the review of new research findings we report on recommendations about anaesthetics and anaesthetic techniques that might be preferable for oncological surgical procedures. cancer growth anaestesia inflammation rast tumorjev anestezija vnetja true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik Neznano 2026-06-24 14:34:52 2026-06-24 14:34:52 2026-06-26 03:42:53 0000-00-00 00:00:00 2024 0 0 str. 9-14, I no. 1 Vol. 58 Mar. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2024-03-01 616-006 1318-2099 10.2478/raon-2024-0012 189574147 RAZ_Potocnik_Iztok_2024.pdf RAZ_Potocnik_Iztok_2024.pdf 1 F3E1F3F5A399903F475EDA9899779494 9c57fecb7817e750a0f6fda0707b65d25484a50c183aa992324c223ab81abea1 3bd3ecd5-6fc9-11f1-98c5-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46202 Društvo radiologije in onkologije Onkološki inštitut Ljubljana 0 0 0