20.500.12556/DiRROS-30435 Current Operating Procedure (COP) for Bleomycin ElectroScleroTherapy (BEST) of low-flow vascular malformations Trenutni operativni postopek (COP) za elektroskleroterapijo z bleomicinom (BEST) pri žilnih malformacijah z nizkim pretokom Bleomycin ElectroScleroTherapy (BEST) is a new approach in the treatment of vascular malformations. After bleomycin is administered to the malformation, electric pulses are applied to the target area to enhance the effectiveness of bleomycin. The mode of action is comparable to the effect of electrochemotherapy on tumour vasculature. For the wider and safer use of BEST in the clinical treatment of low-flow vascular malformations, this Current Operating Procedure (COP) is being prepared. It is a proposal for the clinical standardisation of BEST using the Cliniporator® as the electrical pulse generator with its associated electrodes. The electrical parameters considered in this protocol are those validated by the European Standard Operating Procedures for Electrochemotherapy (ESOPE) with the Cliniporator®. Conclusions General requirements are proposed, and, depending on the type of lesion, local skills and the availability of radiological equipment, two technical approaches of BEST are described based on ultrasound guided intervention or combined ultrasound and fluoroscopic guided intervention. low-flow vascular malformations bleomycin sclerotherapy bleomycin electrosclerotherapy true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik Neznano 2026-06-24 14:31:52 2026-06-24 14:31:52 2026-06-26 03:42:44 0000-00-00 00:00:00 2024 0 0 str. 469-479, I no. 4 Vol. 58 Dec. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2024-12-01 602.6/.7 1318-2099 10.2478/raon-2024-0061 224028419 RAZ_Muir_Tobian_2024.pdf RAZ_Muir_Tobian_2024.pdf 1 9B7BA44320AEF122BBFA7A8B36A61370 f9f1e6b5579024d452a644b61a97a12f26bb5047e1eb043d0f0eb3230656c0f2 de55f64e-6fc8-11f1-98c5-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46199 Društvo radiologije in onkologije 0 0 0