20.500.12556/DiRROS-30412 Sarcopenic obesity in cancer Sarkopenična debelost in rak Sarcopenic obesity is a relatively new term. It is a clinical condition characterized by sarcopenia (loss of muscle mass and function) and obesity (increase in fat mass) that mainly affects older adults. As the incidence of sarcopenia and obesity increases worldwide, sarcopenic obesity is becoming a greater problem also in cancer patients. In fact, sarcopenic obesity is associated with poorer treatment outcomes, longer hospital stays, physical disability, and shorter survival in several cancers. Oxidative stress, lipotoxicity, and systemic inflammation, as well as altered expression of skeletal muscle anti-inflammatory myokines in sarcopenic obesity, are also associated with carcinogenesis. Conclusions. Reported prevalence of sarcopenic obesity in cancer varies because of heterogeneity in definitions and variability in diagnostic criteria used to estimate the prevalence of sarcopenia and obesity. Therefore, the aim of this review is to describe the definitions, prevalence, and diagnostic criteria as well as the mechanisms that cancer has in common with sarcopenic obesity. sarcopenia obesity cancer inflammation sarkopenija debelost onkologija vnetja true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik Neznano 2026-06-24 12:14:33 2026-06-24 12:14:34 2026-06-25 03:51:30 0000-00-00 00:00:00 2024 0 0 str. 1-8, I no. 1 Vol. 58 Mar. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2024-03-01 616-006 1318-2099 10.2478/raon-2024-0011 186658051 RAZ_Jurdana_Mihaela_2024.pdf RAZ_Jurdana_Mihaela_2024.pdf 1 5EB35325588DBC2282412D497AB54EB9 d887ee4596a83cc3045e105e8ceb536fe4d93d06c035d7c7497d611d03b1e171 c200116f-6fb5-11f1-98c5-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=46151 Društvo radiologije in onkologije Onkološki inštitut Ljubljana 0 0 0