20.500.12556/DiRROS-30314 PeptideVisualizer a novel software solution for PROTOMAP analysis PeptideVisualizer: a novel software solution for PROTOMAP analysis PeptideVisualizer is an open-source software for PROTOMAP analysis, offering an intuitive graphical user interface and command-line compatibility. The software processes mass spectrometry data output from MaxQuant to visualize protein migration in polyacrylamide gel electrophoresis and sequence coverage. In addition, it integrates information regarding protein secondary structure and features from the UniProt database to visualize them within comprehensive peptographs. These features allow us to assess the occurrence of a proteolytic event based on sequence context and peptides abundance. The key advantages of PeptideVisualizer include the integration of quantitative information, handling of multiple experiments with biological replicates, and the introduction of a novel mismatch factor─a metric designed to rapidly identify proteolytic events. Herein, the software was validated in an apoptosis-related data set, demonstrating its effectiveness and usefulness in large-scale proteomic data analysis. proteolysis proteases PeptideVisualizer proteoliza proteaze PeptideVisualizer true false true American Chemical Society ZDA Angleški jezik Slovenski jezik © 2026 The Authors. Neznano 2026-06-19 12:14:18 2026-06-19 12:14:18 2026-06-20 03:51:45 0000-00-00 00:00:00 2026 0 0 Nasl. z nasl. zaslona; Soavtorji: Sara Ivanovski, Tilen Sever, Boris Turk, Marko Fonović; Opis vira z dne 16. 5. 2026; str. 2591-2597 iss. 5 Vol. 25 May 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 2025-12-09 2026-04-03 2026-04-15 577 1535-3907 10.1021/acs.jproteome.5c01209 281770243 https://pubs.acs.org/doi/10.1021/acs.jproteome.5c01209?ref=pdf 1 deed5146-6bb6-11f1-be3d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45971 RAZ_Kolaric_Matej_2026.pdf RAZ_Kolaric_Matej_2026.pdf 1 DD3B84A4B5BA5ADE825D2FEF68BE47C7 55aee516f6be1230a7ee2312d91aca56e45451e6cb0ecdd5d66c44019cd41d48 562e8a75-6bb7-11f1-be3d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45972 Institut Jožef Stefan 0 0 0