20.500.12556/DiRROS-30279 Advanced magnetic resonance imaging techniques for structural and functional assessment of salivary glands Background: Diagnostic paradigms for salivary gland disorders have undergone a radical transformation, shifting from purely morphological descriptions toward multi-parametric tissue characterization. This review evaluates the clinical efficacy of advanced magnetic resonance imaging (MRI) techniques, specifically quantitative T2 mapping and arterial spin labelling (ASL), in order to provide objective biomarkers for glandular pathophysiology. The use of pseudocontinuous ASL (pCASL) for non-invasive perfusion assessment and multi-dynamic multi-echo (MDME) sequences for quantitative mapping was highlighted in a methodical synthesis of recent research. Quantitative T2 mapping demonstrates high diagnostic accuracy in identifying glandular dysfunction; patients with hyposalivation exhibit significantly elevated T2 relaxation times (mean 91.85 ± 8.24 ms) compared to healthy controls (mean 80.69 ± 6.42 ms, p < 0.0001). ASL imaging reveals that parotid glands in Sjögren’s syndrome are hyperemic at rest (59.2 ± 22.8 mL/min/100g) but shows dysfunctional microvascular regulation after stimulation. Furthermore, apparent diffusion coefficient (ADC) values effectively differentiate pleomorphic adenomas (> 1.4 × 10–3 mm2/s) from malignant lesions. Conclusions: Advanced MRI provides robust, non-invasive metrics for monitoring radiation-induced damage and assessing the restorative impact of hyperbaric oxygen therapy (HBOT). By facilitating the shift to precision radiology in head and neck medicine, these technologies greatly improve patient quality of life and therapeutic planning. salivary glands xerostomia MRI perfusion imaging difusion imaging hyperbaric oxygen radiology oncology žleze slinavke kserostomija magnetna resonanca (MR) perfuzijsko slikanje difuzijsko slikanje hiperbarični kisik true false true Association of Radiology and Oncology Ljubljana Angleški jezik Slovenski jezik Neznano 2026-06-18 10:58:08 2026-06-18 10:58:09 2026-06-19 03:51:59 0000-00-00 00:00:00 2026 0 0 str. 1-10 no. [Ahead of print] Vol. 2026 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 2026-01-01 616-006 1318-2099 10.2478/raon-2026-0025 278642947 https://reference-global.com/article/10.2478/raon-2026-0025 1 72fb2ee7-6aeb-11f1-be3d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45898 RAZ_Vidmar_Jernej_2026.pdf RAZ_Vidmar_Jernej_2026.pdf 1 EBAB099B03836089FA235150A34BE4D7 8c61dcac1ac76803c15837e5fcace656294231691670c28471d9024ff2eac2f3 9aa41ba0-6aeb-11f1-be3d-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45900 Društvo radiologije in onkologije 0 0 0