20.500.12556/DiRROS-30015 Characterization and management of stable coronary artery disease in patients undergoing transcatheter aortic valve implantation Abstract: Background/Objectives: To date, data regarding the characteristics and management of obstructive, stable coronary artery disease (CAD) encountered in patients undergoing transcatheter aortic valve implantation (TAVI) are sparse. The aim of the study was to analyze granular details, treatment, and outcomes of patients undergoing TAVI with obstructive, stable CAD from real-world practice. Methods: REVASC-TAVI (Management of myocardial REVASCularization in patients undergoing Transcatheter Aortic Valve Implantation with coronary artery disease) is an investigatorinitiated, multicenter registry, which collected data from patients undergoing TAVI with obstructive stable CAD found during the pre-TAVI work-up. Results: A total of 2025 patients from 30 centers worldwide with complete follow-up were included in the registry. Most patients had single-vessel CAD (56.1%). An involvement of proximal coronary tracts was detected in 62.5% of cases, with 12.0% of patients having CAD in left main (LM). Most patients received percutaneous coronary intervention (PCI) (n = 1617, 79.9%), especially those with proximal CAD (90.4%). At 2 years, the rates of all-cause death [Kaplan–Meier (KM) estimates 20.1% vs. 18.8%, plog-rank = 0.86] and of the composite of all-cause death, stroke, myocardial infarction, and rehospitalization for heart failure (KM estimates 29.7% vs. 27.5%, plog-rank = 0.82) did not differ between patients undergoing PCI and those who were not. Conclusions: Patients undergoing TAVI with obstructive CAD more commonly had a single-vessel disease and an involvement of proximal coronary tracts. They were commonly treated with PCI, with similar outcomes compared to those treated conservatively transcatheter aortic valve implantation coronary artery disease percutaneous coronary intervention true false true Angleški jezik Ni določen Neznano 2026-06-11 13:20:55 2026-06-11 13:20:55 2026-06-12 03:54:45 0000-00-00 00:00:00 2024 0 0 Nasl. z nasl. zaslona; Opis vira z dne 12. 8. 2024; str. 1-15 iss. 12 Vol. 13 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 61 2077-0383 10.3390/jcm13123497 204196611 RAZ_Sammartino_Sofia_2024.pdf RAZ_Sammartino_Sofia_2024.pdf 1 59BEFB7595B72A9BE85A241178BD023B 6cc5bb2c6894d7fb58f4258e3bf7c53450d9e6b1ff7cd3a3024766c3fb9a8367 ba48a047-6587-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45238 https://www.mdpi.com/2077-0383/13/12/3497 1 9e7de6cc-6587-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45237 Univerzitetni klinični center Ljubljana 0 0 0