20.500.12556/DiRROS-29960 Incidence of symptomatic Lyme borreliosis in nine European countries Objectives: To better understand the Lyme borreliosis (LB) burden in Europe, we aimed to estimate the incidence of symptomatic Borrelia burgdorferi sensu lato (Bbsl) infections after adjusting public health LB surveillance data for under-detection of symptomatic Bbsl infections. Methods: Data from seroprevalence studies and estimates of the symptomatic proportion and duration of antibody detection in Bbsl-infected individuals, derived from reviews of the published literature, were used to adjust public health LB surveillance data to estimate the incidence of symptomatic Bbsl infection in nine European countries from 2018 to 2022. Results: The prevalence of anti-Bbsl antibodies ranged from 2.3% in Romania to 9.4% in Germany. Under- detection multipliers varied across surveillance systems; using 10-year duration of antibody detection, multipliers were 2.4-10.5 in countries reporting all LB cases and 54.6-722.2 in countries reporting only Lyme neuroborreliosis cases. The incidence of symptomatic Bbsl infection adjusted for under-detection was highest in Finland, Germany, Norway, Poland, and Switzerland, intermediate in the Czech Republic and Denmark, and lowest in Ireland and Romania. Conclusion: Adjustment of LB surveillance for under-detection found a high incidence of symptomatic Bbsl infection in several European countries. Differences in LB surveillance systems should be considered when comparing surveillance data between countries and when estimating LB disease burden. lyme disease epidemiology disease burden surveillance seroprevalence tickborne diseases true false true Angleški jezik Ni določen Neznano 2026-06-10 12:29:06 2026-06-10 12:29:06 2026-06-11 03:47:35 0000-00-00 00:00:00 2024 0 0 str. 1-8 [article no.] ǂ107242 Vol. 149 Dec. 2024 0000-00-00 Zaloznikova Objavljeno NiDoloceno 0000-00-00 0000-00-00 0000-00-00 578.834 1201-9712 10.1016/j.ijid.2024.107242 218543619 RAZ_Angulo_Frederick_J._2024.pdf RAZ_Angulo_Frederick_J._2024.pdf 1 862D4242136650FF67A71EBC30679AF6 264d1821057d17c506dd8b53e9b768d9cef53fd6863e134a011fadd4f729f14c 621864a2-64b7-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45125 https://www.ijidonline.com/article/S1201-9712(24)00313-8/fulltext 0 36c01fbb-64b7-11f1-9215-001a4af901a5 https://dirros.openscience.si/Dokument.php?lang=slv&id=45124 Univerzitetni klinični center Ljubljana 0 0 0